Bioassay Guided Fractionation Identified Hederagenin as a Major Cytotoxic Agent from Cyclocarya paliurus Leaves

Planta Medica

Volumn 82, Issue 1-2, 2015, Pages 171-179

  Gao, Ying ^a   He, Chunnian ^b   Bi, Wu ^b   Wu, Guofan ^c   Altman, Elliot ^a  

^a MIDDLE TENNESSEE STATE UNIVERSITY   (United States)

^b INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^c NORTHWEST NORMAL UNIVERSITY   (China)

Author keywords

Cyclocarya paliurus; cytotoxicity; hederagenin; Juglandaceae; NF B activation; pentacyclic triterpenoids

Indexed keywords

ASIATIC ACID; BAYOGENIN; CYCLOCARIC ACID A; CYTOTOXIC AGENT; HEDERAGENIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYRICADIOL; OLEANOLIC ACID; STAUROSPORINE; TARAXEROL; TRITERPENOID; UNCLASSIFIED DRUG; URSOLIC ACID; ANTINEOPLASTIC AGENT; HERBACEOUS AGENT;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BIOASSAY; BIOASSAY GUIDED FRACTIONATION; BIOLOGICAL ACTIVITY; CANCER CELL LINE; CELL MEMBRANE PERMEABILITY; CHEMICAL BOND; CONTROLLED STUDY; CYCLOCARYA PALIURUS; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PLANT LEAF; STRUCTURE ACTIVITY RELATION; TEA; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; FRACTIONATION; ISOLATION AND PURIFICATION; JUGLANDACEAE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CHEMICAL FRACTIONATION; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; HUMANS; JUGLANDACEAE; MOLECULAR STRUCTURE; OLEANOLIC ACID; PLANT LEAVES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84954144241     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0035-1557900     Document Type: Article

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