Triterpene acids from Euscaphis japonica and assessment of their cytotoxic and anti-no activities

Planta Medica

Volumn 78, Issue 14, 2012, Pages 1584-1590

  Zhang, Li Jie ^a   Cheng, Jing Jy ^a,b   Liao, Chia Ching ^a   Cheng, Hui Ling ^a   Huang, Hung Tse ^a   Kuo, Li Mingyang ^a   Kuo, Yao Haur ^a,c  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

anti NO production; cytotoxicity; euscaphic acids GL; Euscaphis japonica; Staphyleaceae; triterpenoids

Indexed keywords

1ALPHA,3BETA DIHYDROXY 12 OLEANEN 28 OIC ACID; 2ALPHA,3ALPHA,23 TRIHYDROXYOLEAN 12 EN 28 OIC ACID; 2ALPHA,3BETA,19ALPHA TRIHYDROXYURS 12 ENE 23,28 DIOIC ACID 23 METHYL ESTER; 3BETA,23 DIHYDROXY 1 OXO OLEAN 12 EN 28 OIC ACID; ARJUNIC ACID; CAROLIGNAN A; CAROLIGNAN B; DOXORUBICIN; HEDERAGENIN; ILEXOSAPOGENIN A; LIGNAN; MASLINIC ACID; NITRIC OXIDE; TORMENTIC ACID; TORMENTIC ACID G; TORMENTIC ACID H; TORMENTIC ACID I; TORMENTIC ACID J; TORMENTIC ACID K; TORMENTIC ACID L; TRITERPENE DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG; VERGATIC ACID;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; EUSCAPHIS JAPONICA; HUMAN; HUMAN CELL; IC 50; MEDICINAL PLANT; NONHUMAN;

ANGIOSPERMS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; INHIBITORY CONCENTRATION 50; LIGNANS; MACROPHAGES; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE; OLEANOLIC ACID; PLANT EXTRACTS; POLYSACCHARIDES; TRITERPENES;

EUSCAPHIS JAPONICA; STAPHYLEACEAE;

EID: 84867064106     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0032-1315040     Document Type: Article

References (13)

1. Huang T. C. Flora of Taiwan, Volume 3. Taipei Department of Botany, National Taiwan University: 1993; 661
2. Jiangsu Modern Medicine College Dictionary of Chinese materia medica, Volume 2. Shanghai Shanghai Scientific and Technical Publishers: 2004; 5154 5155
3. Cheng J. J., Zhang L. J., Cheng H. L., Chiou C. T., Lee I. J., Kuo Y. H. Cytotoxic hexacyclic triterpene acids from Euscaphis japonica. J Nat Prod: 2010; 73 1655 1658
4. Zhang L. J., Liu H. K., Hsiao P. C., Kuo Y. LM, Lee I. J., Wu T. S., Chiou W. F., Kuo Y. H. New isoflavonoid glycosides and related constituents from Astragali Radix (Astragalus membranaceus) and their inhibitory activity on nitric oxide production. J Agric Food Chem: 2011; 59 1131 1137
5. Okada Y., Omae A., Okuyama T. A new triterpenoid isolated from Lagerstronemia speciosa (L.) Pers. Chem Pharm Bull: 2003; 51 452 454 (Pubitemid 41694827)
6. Hattori M., Kuo K. P., Shu Y. Z., Tezuka Y., Kikuchi T., Namba T. A triterpene from the fruits of Rubus chingii. Phytochemistry: 1988; 27 3975 3976
7. Amimoto K., Yoshikawa K., Arihara S. Triterpenoid saponins of aquifoliaceous plants. XII. Ilexosides XLVILI from the leaves of Ilex rotunda Thunb. Chem Pharm Bull: 1993; 41 77 80 (Pubitemid 23071626)
8. Ulubelen A., Ayanoglu E. Vergatic acid, a new pentacyclic triterpene from Salvia virgata. Phytochemistry: 1976; 15 309 311
9. Banno N., Akihisa T., Tokuda H., Yasukawa K., Taguchi Y., Akazawa H., Ukiya M., Kimura Y., Suzuki T., Nishino H. Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonica. Biol Pharm Bull: 2005; 28 1995 1999 (Pubitemid 41437099)
10. Ding H. Y., Lin H. C., Teng C. M., Wu Y. C. Phytochemical and pharmacological studies on Chinese Paeonia species. J Chin Chem Soc: 2000; 47 381 388
11. Saxena M., Faridi U., Mishra R., Gupta M. M., Darokar M. P., Srivastava S. K., Singh D., Luqman S., Khanuja S. PS. Cytotoxic agents from Terminalia arjuna. Planta Med: 2007; 73 1486 1490 (Pubitemid 350240508)
12. Abe F., Yamauchi T. Trachelosperosides, glycosides of 19 α -hydroxyursane-type triterpenoids from Trachelospermus asiaticum (Trachelospermum III). Chem Pharm Bull: 1987; 35 1748 1754
13. Paula V. F., Barbosa L. CA, Howarth O. W., Demuner A. J., Cass Q. B., Vieira I. JC. Lignans from Ochroma lagopus Swartz. Tetrahedron: 1995; 51 12453 12462