Polyphosphazene vesicles for co-delivery of doxorubicin and chloroquine with enhanced anticancer efficacy by drug resistance reversal

International Journal of Pharmaceutics

Volumn 498, Issue 1-2, 2016, Pages 70-81

  Xu, Jing ^a   Zhu, Xiumei ^b   Qiu, Liyan ^a,c  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

Author keywords

Chloroquine; Combination cancer therapy; Doxorubicin; Drug resistance; Polymersomes; Polyphosphazene

Indexed keywords

CHLOROQUINE; DOXORUBICIN; DRUG CARRIER; POLY(ETHYLENE GLYCOL) B POLYLACTIDE; POLYMER; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ORGANOPHOSPHORUS COMPOUND; POLY(PHOSPHAZENE);

ACUTE MYELOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CANCER RESISTANCE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; FLOW CYTOMETRY; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HL 60 CELL LINE; HUMAN; HUMAN CELL; HYDROPHOBICITY; IC50; IN VITRO STUDY; MCF 7 CELL LINE; MOLECULAR WEIGHT; PRIORITY JOURNAL; RING OPENING; SUBSTITUTION REACTION; TUMOR SPHEROID; TUMOR XENOGRAFT; ANIMAL; BREAST NEOPLASMS; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; FEMALE; HL-60 CELL LINE; MCF-7 CELL LINE; PHYSIOLOGY; PROCEDURES; TREATMENT OUTCOME; ZEBRA FISH;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CHLOROQUINE; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, NEOPLASM; FEMALE; HL-60 CELLS; HUMANS; MCF-7 CELLS; ORGANOPHOSPHORUS COMPOUNDS; POLYMERS; TREATMENT OUTCOME; XENOGRAFT MODEL ANTITUMOR ASSAYS; ZEBRAFISH;

EID: 84954132789     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.12.003     Document Type: Article

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