메뉴 건너뛰기




Volumn 4, Issue 2, 2015, Pages 1-7

Indoleamine-2,3-dioxygenase (IDO) metabolic activity is detrimental for cervical cancer patient survival

Author keywords

Cervical cancer; IDO; Kyn Trp ratio; Kynurenine; Tryptophan

Indexed keywords

3 HYDROXYKYNURENINE; AMINO ACID; CISPLATIN; IMMUNOMODULATING AGENT; INDOLEAMINE 2,3 DIOXYGENASE; KYNURENINE; TRYPTOPHAN;

EID: 84954094214     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/2162402X.2014.981457     Document Type: Article
Times cited : (83)

References (50)
  • 4
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001; 357:539-45.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 5
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 84875261622 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase and metabolic control of immune responses
    • Munn DH, Mellor AL. Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol. 2013 Mar;34(3):137-43.
    • (2013) Trends Immunol , vol.34 , Issue.3 , pp. 137-143
    • Munn, D.H.1    Mellor, A.L.2
  • 11
    • 0025944659 scopus 로고
    • Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism
    • Taylor MW, Feng GS. Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism. FASEB J 1991; 5:2516-22.
    • (1991) FASEB J , vol.5 , pp. 2516-2522
    • Taylor, M.W.1    Feng, G.S.2
  • 12
    • 58749112572 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients’ sera by HPLC and is inducible by IFN-y
    • Corm S, Berthon C, Imbenotte M, Biggio V, Lhermitte M, Dupont C, Briche I, Quesnel B. Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients’ sera by HPLC and is inducible by IFN-y. Leukemia Res 2009; 33:490-4.
    • (2009) Leukemia Res , vol.33 , pp. 490-494
    • Corm, S.1    Berthon, C.2    Imbenotte, M.3    Biggio, V.4    Lhermitte, M.5    Dupont, C.6    Briche, I.7    Quesnel, B.8
  • 13
    • 46249124461 scopus 로고    scopus 로고
    • Immune escape as a fundamental trait of cancer: Focus on IDO
    • Prendergast GC. Immune escape as a fundamental trait of cancer: focus on IDO. Oncogene 2008; 27:3889-900.
    • (2008) Oncogene , vol.27 , pp. 3889-3900
    • Prendergast, G.C.1
  • 15
    • 84886945280 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in Stage III non-small cell lung cancer
    • Creelan BC, Antonia S, Bepler G, Garrett TJ, Simon GR, Soliman HH. Indoleamine 2,3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in Stage III non-small cell lung cancer. Oncoimmunol 2013; 3: e23428.
    • (2013) Oncoimmunol , vol.3 , pp. e23428
    • Creelan, B.C.1    Antonia, S.2    Bepler, G.3    Garrett, T.J.4    Simon, G.R.5    Soliman, H.H.6
  • 18
    • 79251595590 scopus 로고    scopus 로고
    • Enhanced tryptophan degradation in patients with ovarian carcinoma correlates with several serum soluble immune activation markers
    • Sperner-Unterweger B, Neurauter G, Klieber M, Kurz K, Meraner V, Zeimet A, Fuchs D. Enhanced tryptophan degradation in patients with ovarian carcinoma correlates with several serum soluble immune activation markers. Immunobiol 2011; 216:296-301.
    • (2011) Immunobiol , vol.216 , pp. 296-301
    • Sperner-Unterweger, B.1    Neurauter, G.2    Klieber, M.3    Kurz, K.4    Meraner, V.5    Zeimet, A.6    Fuchs, D.7
  • 20
    • 16244408626 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2, 3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
    • Muller AJ, DuHadaway JB, Donover PS, Sutanto- Ward E, Prendergast GC. Inhibition of indoleamine 2, 3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat Med. 2005; 11:312-9.
    • (2005) Nat Med , vol.11 , pp. 312-319
    • Muller, A.J.1    Duhadaway, J.B.2    Donover, P.S.3    Sutanto- Ward, E.4    Prendergast, G.C.5
  • 23
    • 84855176685 scopus 로고    scopus 로고
    • Upregulated expression of indoleamine 2, 3-dioxygenase in primary breast cancer correlates with increase of infiltrated regulatory T cells in situ and lymph node metastasis
    • Yu J, Sun J, Wang S, Li H, Cao S, Cong Y, Liu J, Ren X. Upregulated expression of indoleamine 2, 3-dioxygenase in primary breast cancer correlates with increase of infiltrated regulatory T cells in situ and lymph node metastasis. Clin Dev Immunol 2011;AI469135.
    • (2011) Clin Dev Immunol , pp. AI469135
    • Yu, J.1    Sun, J.2    Wang, S.3    Li, H.4    Cao, S.5    Cong, Y.6    Liu, J.7    Ren, X.8
  • 24
    • 70149093957 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenaseexpressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells
    • Chung DJ, Rossi M, Romano E, Ghith J, Yuan J, Munn DH, Young JW. Indoleamine 2,3-dioxygenaseexpressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells. Blood 2009; 114:555-63.
    • (2009) Blood , vol.114 , pp. 555-563
    • Chung, D.J.1    Rossi, M.2    Romano, E.3    Ghith, J.4    Yuan, J.5    Munn, D.H.6    Young, J.W.7
  • 25
    • 70350433798 scopus 로고    scopus 로고
    • Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells
    • Jurgens B, Hainz U, Fuchs D, Felzmann T, Heitger A. Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells. Blood 2009; 114:3235-43.
    • (2009) Blood , vol.114 , pp. 3235-3243
    • Jurgens, B.1    Hainz, U.2    Fuchs, D.3    Felzmann, T.4    Heitger, A.5
  • 26
    • 77951938172 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase expression predicts impaired survival of invasive cervical cancer patients treated with radical hysterectomy
    • Inaba T, Ino K, Kajiyama H, Shibata K, Yamamoto E, Kondo S, Umezu T, Nawa A, Takikawa O, Kikkawa F. Indoleamine 2, 3-dioxygenase expression predicts impaired survival of invasive cervical cancer patients treated with radical hysterectomy. Gynecol Oncol 2010; 117:423-8.
    • (2010) Gynecol Oncol , vol.117 , pp. 423-428
    • Inaba, T.1    Ino, K.2    Kajiyama, H.3    Shibata, K.4    Yamamoto, E.5    Kondo, S.6    Umezu, T.7    Nawa, A.8    Takikawa, O.9    Kikkawa, F.10
  • 28
    • 34247862322 scopus 로고    scopus 로고
    • Expression of indoleamine 2, 3-dioxygenase and the recruitment ofFoxp3-expressing regulatory T cells in the development and progression of uterine cervical cancer
    • Nakamura T, Shima T, Saeki A, Hidaka T, Nakashima A, Takikawa O, Saito S. Expression of indoleamine 2, 3-dioxygenase and the recruitment ofFoxp3-expressing regulatory T cells in the development and progression of uterine cervical cancer. Cancer Sci 2007; 98:874-81.
    • (2007) Cancer Sci , vol.98 , pp. 874-881
    • Nakamura, T.1    Shima, T.2    Saeki, A.3    Hidaka, T.4    Nakashima, A.5    Takikawa, O.6    Saito, S.7
  • 29
    • 50149109644 scopus 로고    scopus 로고
    • Evolving immunosuppressive microenvironment during human cervical carcinogenesis
    • Kobayashi A, Weinberg V, Darragh T, Smith-McCune K. Evolving immunosuppressive microenvironment during human cervical carcinogenesis. Mucosal Immunol 2008; 1:412-20.
    • (2008) Mucosal Immunol , vol.1 , pp. 412-420
    • Kobayashi, A.1    Weinberg, V.2    Darragh, T.3    Smith-McCune, K.4
  • 31
    • 84881249760 scopus 로고    scopus 로고
    • Prognostic value of combined serum biomarkers in predicting outcomes in cervical cancer patients
    • Sep 23
    • Li J, Cheng H, Zhang P, Dong Z, Tong HL, Han JD, Guo F, Tian YP. Prognostic value of combined serum biomarkers in predicting outcomes in cervical cancer patients. Clin Chim Acta. 2013 Sep 23; 424:292-7.
    • (2013) Clin Chim Acta , vol.424 , pp. 292-297
    • Li, J.1    Cheng, H.2    Zhang, P.3    Dong, Z.4    Tong, H.L.5    Han, J.D.6    Guo, F.7    Tian, Y.P.8
  • 32
    • 33845920042 scopus 로고    scopus 로고
    • Decreased serum tryptophan concentration predicts poor prognosis in malignant melanoma patients
    • Weinlich G, Murr C, Richardsen L, Winkler C, Fuchs D. Decreased serum tryptophan concentration predicts poor prognosis in malignant melanoma patients. Dermatology 2007; 214:8-14.
    • (2007) Dermatology , vol.214 , pp. 8-14
    • Weinlich, G.1    Murr, C.2    Richardsen, L.3    Winkler, C.4    Fuchs, D.5
  • 33
    • 84890857180 scopus 로고    scopus 로고
    • Antitumour agents as inhibitors of tryptophan 2, 3-dioxygenase
    • Pantouris G, Mowat CG. Antitumour agents as inhibitors of tryptophan 2, 3-dioxygenase. Biochem Biophys Res Commun 2014; 443:28-31.
    • (2014) Biochem Biophys Res Commun , vol.443 , pp. 28-31
    • Pantouris, G.1    Mowat, C.G.2
  • 34
    • 19344377474 scopus 로고    scopus 로고
    • GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
    • Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, Mellor AL. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity 2005; 22:633-42.
    • (2005) Immunity , vol.22 , pp. 633-642
    • Munn, D.H.1    Sharma, M.D.2    Baban, B.3    Harding, H.P.4    Zhang, Y.5    Ron, D.6    Mellor, A.L.7
  • 36
    • 42249084713 scopus 로고    scopus 로고
    • Inverse correlation between tumoural indo- leamine 2,3-dioxygenase expression and tumour-infiltrating lymphocytes in endometrial cancer: Its association with disease progression and survival
    • Ino K, Yamamoto E, Shibata K, Kajiyama H, Yoshida N, Terauchi M, Nawa A, Nagasaka T, Takikawa O, Kikkawa F. Inverse correlation between tumoural indo- leamine 2,3-dioxygenase expression and tumour-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival. Clin Cancer Res 2008; 14:2310-7.
    • (2008) Clin Cancer Res , vol.14 , pp. 2310-2317
    • Ino, K.1    Yamamoto, E.2    Shibata, K.3    Kajiyama, H.4    Yoshida, N.5    Terauchi, M.6    Nawa, A.7    Nagasaka, T.8    Takikawa, O.9    Kikkawa, F.10
  • 37
    • 0037136328 scopus 로고    scopus 로고
    • Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2, 3-dioxygenase
    • Frumento G, Rotondo R, Tonetti M, Damonte G, Benatti U, Ferrara GB. Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2, 3-dioxygenase. J Exp Med 2002; 196:459-68.
    • (2002) J Exp Med , vol.196 , pp. 459-468
    • Frumento, G.1    Rotondo, R.2    Tonetti, M.3    Damonte, G.4    Benatti, U.5    Ferrara, G.B.6
  • 38
    • 61449220940 scopus 로고    scopus 로고
    • Immunosuppressive myeloid-derived suppressor cells can be converted into immunogenic APCs with the help of activated NKT cells: An alternative cell-based antitumor vaccine
    • Ko HJ, Lee JM, Kim YJ, Kim YS, Lee KA, Kang CY. Immunosuppressive myeloid-derived suppressor cells can be converted into immunogenic APCs with the help of activated NKT cells: an alternative cell-based antitumor vaccine. J Immunol 2009; 182:1818-28.
    • (2009) J Immunol , vol.182 , pp. 1818-1828
    • Ko, H.J.1    Lee, J.M.2    Kim, Y.J.3    Kim, Y.S.4    Lee, K.A.5    Kang, C.Y.6
  • 39
    • 76249111086 scopus 로고    scopus 로고
    • IDO inhibits T-cell function through suppressing Vav1 expression and activation
    • Li R, Wei F, Yu J. IDO inhibits T-cell function through suppressing Vav1 expression and activation. Cancer Biol Ther 2009; 8:1402-8.
    • (2009) Cancer Biol Ther , vol.8 , pp. 1402-1408
    • Li, R.1    Wei, F.2    Yu, J.3
  • 40
    • 80052833629 scopus 로고    scopus 로고
    • Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells
    • Sun J, Yu J, Li H, Yang L, Wei F, Yu W, Liu J, Ren X. Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells. J Exp Cliun CancRes 2011;30:82-92.
    • (2011) J Exp Cliun Cancres , vol.30 , pp. 82-92
    • Sun, J.1    Yu, J.2    Li, H.3    Yang, L.4    Wei, F.5    Yu, W.6    Liu, J.7    Ren, X.8
  • 42
    • 84875462761 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer
    • Apr 1
    • Yu J, Du W, Yan F, Wang Y, Li H, Cao S, Yu W, Shen C, Liu J, Ren X. Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer. J Immunol. 2013 Apr 1; 190(7):3783-97.
    • (2013) J Immunol , vol.190 , Issue.7 , pp. 3783-3797
    • Yu, J.1    Du, W.2    Yan, F.3    Wang, Y.4    Li, H.5    Cao, S.6    Yu, W.7    Shen, C.8    Liu, J.9    Ren, X.10
  • 45
    • 42249094710 scopus 로고    scopus 로고
    • Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: Which variable determines survival of cervical cancer patients?
    • Apr 1
    • Jordanova ES, Gorter A, Ayachi O, Prins F, Durrant LG, Kenter GG, van der Burg SH, Fleuren GJ. Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: which variable determines survival of cervical cancer patients? Clin Cancer Res. 2008 Apr 1;14(7):2028-35.
    • (2008) Clin Cancer Res , vol.14 , Issue.7 , pp. 2028-2035
    • Jordanova, E.S.1    Gorter, A.2    Ayachi, O.3    Prins, F.4    Durrant, L.G.5    Kenter, G.G.6    Van Der Burg, S.H.7    Fleuren, G.J.8
  • 46
    • 84890522502 scopus 로고    scopus 로고
    • Indoleamine 2,3- dioxygenase 2 (IDO2) and the kynurenine pathway: Characteristics and potential roles in health and disease
    • Fatokun AA, Hunt NH, Ball HJ. Indoleamine 2,3- dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease. Amino Acids 2013; 45:1319-29.
    • (2013) Amino Acids , vol.45 , pp. 1319-1329
    • Fatokun, A.A.1    Hunt, N.H.2    Ball, H.J.3
  • 47
    • 84880688294 scopus 로고    scopus 로고
    • IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D- 1-methyl-tryptophan
    • Metz R, Rust S, Duhadaway JB, Mautino MR, Munn DH, Vahanian NN, Link CJ, Prendergast GC. IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: a novel IDO effector pathway targeted by D- 1-methyl-tryptophan. Oncoimmunol 2012; 1:1460-8.
    • (2012) Oncoimmunol , vol.1 , pp. 1460-1468
    • Metz, R.1    Rust, S.2    Duhadaway, J.B.3    Mautino, M.R.4    Munn, D.H.5    Vahanian, N.N.6    Link, C.J.7    Prendergast, G.C.8
  • 49
    • 84884545929 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase inhibitors: A patent review (2008-2012)
    • Dolusic E, Frederick R. Indoleamine 2,3-dioxygenase inhibitors: a patent review (2008-2012). Expert Opin Ther Pat 2013; 23:1367-81.
    • (2013) Expert Opin Ther Pat , vol.23 , pp. 1367-1381
    • Dolusic, E.1    Frederick, R.2
  • 50
    • 60449106709 scopus 로고    scopus 로고
    • Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry
    • de Jong WH, Smit R, Bakker SJ, et al. Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2009; 877(7):603-9.
    • (2009) J Chromatogr B Analyt Technol Biomed Life Sci , vol.877 , Issue.7 , pp. 603-609
    • De Jong, W.H.1    Smit, R.2    Bakker, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.