Tumor-specific pH-responsive peptide-modified pH-sensitive liposomes containing doxorubicin for enhancing glioma targeting and anti-tumor activity

Journal of Controlled Release

Volumn 222, Issue , 2016, Pages 56-66

  Zhao, Yang ^a   Ren, Wei ^a   Zhong, Ting ^a   Zhang, Shuang ^a   Huang, Dan ^a   Guo, Yang ^a   Yao, Xin ^a   Wang, Chao ^a   Zhang, Wei Qiang ^a   Zhang, Xuan ^a   Zhang, Qiang ^a,b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Anti tumor activity; Glioma; pH sensitive liposomes; Targeting; Tumor specific pH responsive peptide

Indexed keywords

CELLS; CYTOLOGY; FILM PREPARATION; GRADIENT METHODS; LIPOSOMES; MAMMALS; PEPTIDES; PH SENSORS;

ANTI-TUMOR ACTIVITIES; GLIOMA; PH-RESPONSIVE PEPTIDES; PH-SENSITIVE LIPOSOMES; TARGETING;

TUMORS;

AMMONIUM SULFATE; DOXORUBICIN; LIPOSOME; PEPTIDE; PEPTIDE H7K(R2 )2; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; H7K(R2)2 PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG RELEASE; DRUG TARGETING; FEMALE; FLOW CYTOMETRY; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL DELIVERY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; TUMOR MICROENVIRONMENT; ANIMAL; BAGG ALBINO MOUSE; BRAIN NEOPLASMS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; NUDE MOUSE; RAT; TUMOR CELL LINE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG LIBERATION; GLIOMA; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MICE; MICE, INBRED BALB C; MICE, NUDE; PEPTIDES; RATS; TUMOR MICROENVIRONMENT;

EID: 84954090435     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.12.006     Document Type: Article

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