High tumor penetration of paclitaxel loaded pH sensitive cleavable liposomes by depletion of tumor collagen i in breast cancer

ACS Applied Materials and Interfaces

Volumn 7, Issue 18, 2015, Pages 9691-9701

  Zhang, Li ^a   Wang, Yang ^a   Yang, Yuting ^a   Liu, Yayuan ^a   Ruan, Shaobo ^a   Zhang, Qianyu ^a   Tai, Xiaowei ^a   Chen, Jiantao ^a   Xia, Tai ^a   Qiu, Yue ^a   Gao, Huile ^a   He, Qin ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

cleavable PEG; drug delivery; drug penetration; losartan; pH sensitive

Indexed keywords

COLLAGEN; DRUG DELIVERY; IODINE; LIPOSOMES; MOBILE SECURITY; NANOPARTICLES; PEPTIDES; PH EFFECTS; PH SENSORS; TUMORS;

ANTI-TUMOR EFFICACY; COMBINATION STRATEGIES; DRUG PENETRATION; ENHANCED PERMEABILITY AND RETENTION EFFECTS; IN-VIVO EXPERIMENTS; LOSARTAN; PH SENSITIVE; TUMOR ACCUMULATION;

CHLORINE;

COLLAGEN TYPE 1; EVANS BLUE; LIPOSOME; LOSARTAN; PACLITAXEL;

ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; BREAST NEOPLASMS; DRUG DELIVERY SYSTEM; DRUG EFFECTS; ENDOCYTOSIS; FEMALE; HUMAN; METABOLISM; PARTICLE SIZE; PH; STATIC ELECTRICITY; TISSUE DISTRIBUTION; TREATMENT OUTCOME; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; COLLAGEN TYPE I; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; EVANS BLUE; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; LOSARTAN; MICE, INBRED BALB C; PACLITAXEL; PARTICLE SIZE; STATIC ELECTRICITY; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

EID: 84929207575     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b01473     Document Type: Article

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