The sphingosine-1-phosphate lyase (LegS2) contributes to the restriction of Legionella pneumophila in murine macrophages

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Khweek, Arwa Abu ^a   Kanneganti, Apurva ^b   Guttridge, Denis C D ^c   Amer, Amal O ^b  

^a BIRZEIT UNIVERSITY   (Palestine)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CASPASE 3; CASPASE 7; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; PROTEIN LEGS2; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BACTERIAL SECRETION SYSTEM; CALCIUM BINDING PROTEIN; CASP7 PROTEIN, MOUSE; IPAF PROTEIN, MOUSE; LYASE; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE 1-PHOSPHATE LYASE (ALDOLASE);

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIAL LOAD; BONE MARROW DERIVED MACROPHAGE; CELL ELONGATION; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; LEGIONELLA PNEUMOPHILA; LYSOSOME; MACROPHAGE; MITOCHONDRION; MONOCYTE DERIVED MACROPHAGE; MOUSE; NONHUMAN; PHAGOSOME; ANALOGS AND DERIVATIVES; ANIMAL; BACTERIAL SECRETION SYSTEM; DISEASE RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; LEGIONNAIRE DISEASE; MEMBRANE FUSION; METABOLISM; MICROBIOLOGY; NONOBESE DIABETIC MOUSE; PATHOGENICITY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE;

ALDEHYDE-LYASES; ANIMALS; APOPTOSIS REGULATORY PROTEINS; BACTERIAL SECRETION SYSTEMS; CALCIUM-BINDING PROTEINS; CASPASE 1; CASPASE 3; CASPASE 7; DISEASE RESISTANCE; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; LEGIONELLA PNEUMOPHILA; LEGIONNAIRES' DISEASE; LYSOPHOSPHOLIPIDS; LYSOSOMES; MACROPHAGES; MEMBRANE FUSION; MICE; MICE, INBRED NOD; NF-KAPPA B; PHAGOSOMES; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; SPHINGOSINE;

EID: 84954069696     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0146410     Document Type: Article

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