Vitamin D content in human breast milk: A 9-mo follow-up study

American Journal of Clinical Nutrition

Volumn 103, Issue 1, 2016, Pages 107-114

  Streym, Susanna Vio ^a   Højskov, Carsten S ^a   Møller, Ulla Kristine ^a   Heickendorff, Lene ^a   Vestergaard, Peter ^b   Mosekilde, Leif ^a   Rejnmark, Lars ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AALBORG UNIVERSITY   (Denmark)

Author keywords

Breastfeeding; Infants; Nutrition; Rickets; Vitamin D

Indexed keywords

CALCIFEDIOL; COLECALCIFEROL; ERGOCALCIFEROL; VITAMIN D; 25-HYDROXYVITAMIN D;

ADULT; ARTICLE; BLOOD SAMPLING; BREAST MILK; CLINICAL TRIAL; COHORT ANALYSIS; COLOSTRUM; FEMALE; HUMAN; INFANT; LACTATION; LIMIT OF DETECTION; MATERNAL BLOOD; MATERNAL PLASMA; NUTRIENT CONTENT; PUERPERIUM; SEASONAL VARIATION; VITAMIN BLOOD LEVEL; VITAMIN INTAKE; ANALOGS AND DERIVATIVES; BLOOD; BREAST FEEDING; CALORIC INTAKE; DIETARY SUPPLEMENT; FOLLOW UP; INFANT NUTRITION; MATERNAL NUTRITION; METABOLISM; NEWBORN; PREGNANCY; VITAMIN D DEFICIENCY; YOUNG ADULT;

ADULT; BREAST FEEDING; CALCIFEDIOL; CHOLECALCIFEROL; DIETARY SUPPLEMENTS; ENERGY INTAKE; ERGOCALCIFEROLS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFANT, NEWBORN; LACTATION; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MILK, HUMAN; POSTPARTUM PERIOD; PREGNANCY; VITAMIN D; VITAMIN D DEFICIENCY; YOUNG ADULT;

EID: 84953865266     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.115.115105     Document Type: Article

References (34)

1. Dawodu A, Agarwal M, Hossain M, Kochiyil J, Zayed R. Hypo-vitaminosis D and vitamin D deficiency in exclusively breast-feeding infants and their mothers in summer: a justification for vitamin D supplementation of breast-feeding infants. J Pediatr 2003;142:169-73.
2. Beck-Nielsen SS. Rickets in Denmark. Dan Med J 2012;59:B4384.
3. Council on Environmental Health, Section on Dermatology, Balk SJ. Ultraviolet radiation: a hazard to children and adolescents. Pediatrics 2011;127:588-97.
4. IOM (Institute of Medicine). Committee to Review Dietary Reference Intakes for Vitamin D and Calcium; Institute of Medicine 2010. Dietary reference intakes for calcium and vitamin D. Washington (DC): The National Academies Press; 2011.
5. Weisman Y, Bawnik JC, Eisenberg Z, Spirer Z. Vitamin D metabolites in human milk. J Pediatr 1982;100:745-8.
6. Cancela L, Le Boulch N, Miravet L. Relationship between the vitamin D content of maternal milk and the vitamin D status of nursing women and breast-fed infants. J Endocrinol 1986;110:43-50.
7. Ala-Houhala M, Koskinen T, Parviainen MT, Visakorpi JK. 25-Hydroxyvitamin D and vitamin D in human milk: effects of supple-mentation and season. Am J Clin Nutr 1988;48:1057-60.
8. Hollis BW, Pittard WB III, Reinhardt TA. Relationships among vitamin D, 25-hydroxyvitamin D, and vitamin D-binding protein concentrations in the plasma and milk of human subjects. J Clin Endocrinol Metab 1986;62:41-4.
9. Reeve LE, Chesney RW, DeLuca HF. Vitamin D of human milk: identification of biologically active forms. Am J Clin Nutr 1982; 36:122-6.
10. Hollis BW, Roos BA, Draper HH, Lambert PW. Vitamin D and its metabolites in human and bovine milk. J Nutr 1981;111:1240-8.
11. Kunz C, Niesen M, von Lilienfeld-Toal H, Burmeister W. Vitamin D, 25-hydroxy-vitamin D and 1, 25-dihydroxy-vitamin D in cow's milk, infant formulas and breast milk during different stages of lactation. Int J Vitam Nutr Res 1984;54:141-8.
12. Takeuchi A, Okano T, Tsugawa N, Tasaka Y, Kobayashi T, Kodama S, Matsuo T. Effects of Ergocalciferol Supplementation on the Concen-tration of Vitamin D and Its Metabolites in Human Milk. J Nutr 1989; 119:1639-46.
13. Greer FR, Hollis BW, Cripps DJ, Tsang RC. Effects of maternal ul-traviolet B irradiation on vitamin D content of human milk. J Pediatr 1984;105:431-3.
14. Parviainen MT, Koskinen T, la-Houhala M, Visakorpi JK. A method for routine estimation of vitamin D activity in human and bovine milk. Acta Vitaminol Enzymol 1984;6:211-9.
15. Specker BL, Tsang RC, Hollis BW. Effect of race and diet on human milk vitamin d and 25-hydroxyvitamin D. Am J Dis Child 1985;139:1134-7.
16. Greibe E1, Lildballe DL, Streym S, Vestergaard P, Rejnmark L, Mosekilde L, Nexo E. Cobalamin and haptocorrin in human milk and cobalamin-related variables in mother and child: a 9-mo longitudinal study. Am J Clin Nutr 2013;98:389-95.
17. Streym S, Kristine Moller U, Rejnmark L, Heickendorff L, Mosekilde L, Vestergaard P. Maternal and infant vitamin D status during the first 9 months of infant life - A cohort study. Eur J Clin Nutr 2013;67:1022-8.
18. Maunsell Z, Wright DJ, Rainbow SJ. Routine isotope-dilution liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of the 25-hydroxy metabolites of vitamins D2 and D3. Clin Chem 2005;51:1683-90.
19. Højskov CS, Heickendorff L, Møller HJ. High-throughput liquid-liquid extraction and LCMSMS assay for determination of circulating 25 (OH) vitamin D3 and D2 in the routine clinical laboratory. Clin Chim Acta 2010;411:114-6.
20. Cashman KD, Seamans KM, Lucey AJ, Stöcklin E, Weber P, Kiely M, Hill TR. Relative effectiveness of oral 25-hydroxyvitamin D3 and vitamin D3 in raising wintertime serum 25-hydroxyvitamin D in older adults. Am J Clin Nutr 2012;95:1350-6.
21. Rejnmark L, Vestergaard P, Heickendorff L, Mosekilde L. De-terminants of plasma PTH and their implication for defining a reference interval. Clin Endocrinol (Oxf) 2011;74:37-43.
22. Greer FR, Hollis BW, Napoli JL. High concentrations of vitamin D2 in human milk associated with pharmacologic doses of vitamin D2. J Pediatr 1984;105:61-4.
23. Hoogenboezem T, Degenhart HJ, Keizer-Schrama SMPF, Bouillon R, Grose WFA, Hackeng WHL, Visser HKA, Vitamin D. Metabolism in breast-fed infants and their mothers. Pediatr Res 1989;25:623-8.
24. Oberhelman SS, Meekins ME, Fischer PR, Lee BR, Singh RJ, Cha SS, Gardner BM, Pettifor JM, Croghan IT, Thacher TD. Maternal vitamin D supplementation to improve the vitamin D status of breast-fed infants: a randomized controlled trial. Mayo Clin Proc 2013;88:1378-87.
25. Hollis BW. Individual quantitation of vitamin D2, vitamin D3, 25-hydroxyvitamin D2, and 25-hydroxyvitamin D3 in human milk. Anal Biochem 1983;131:211-9.
26. Thiele DK, Senti JL, Anderson CM. Maternal vitamin D supplementation to meet the needs of the breastfed infant: a systematic review. J Hum Lact 2013;29:163-70.
27. Olafsdottir AS, Wagner KH, Thorsdottir I, Elmadfa I. Fat-soluble vitamins in the maternal diet, influence of cod liver oil supplementation and impact of the maternal diet on human milk composition. Ann Nutr Metab 2001;45:265-72.
28. Kamao M, Tsugawa N, Suhara Y, Wada A, Mori T, Murata K, Nishino R, Ukita T, Uenishi K, Tanaka K, et al. Quantification of fat-soluble vitamins in human breast milk by liquid chromatography2tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2007;859:192-200.
29. Hanson AL, Metzger LE. Evaluation of increased vitamin D fortification in high-temperature, short-time-processed 2% milk, UHT-processed 2% fat chocolate milk, and low-fat strawberry yogurt. J Dairy Sci 2010;93:801-7.
30. Masood T, Kushwaha RS, Singh R, Sailwal S, Pandey H, Varma A, Singh RK, Cornelissen G. Circadian rhythm of serum 25 (OH) vitamin D, calcium and phosphorus levels in the treatment and management of type-2 diabetic patients. Drug Discov Ther 2015;9:70-4.
31. Piccione G, Assenza A, Grasso F, Caola G. Daily rhythm of circulating fat soluble vitamin concentration (A, D, E and K) in the horse. J Cir-cadian Rhythms 2004;2:3.
32. Tanaka Y, Frank H, DeLuca HF. Biological activity of 1, 25-dihydroxyvitamin D3 in the rat. Endocrinology 1973;92:417-22.
33. Hollis BW, Wagner CL. Vitamin D requirements during lactation: high-dose maternal supplementation as therapy to prevent hypo-vitaminosis D for both the mother and the nursing infant. Am J Clin Nutr 2004;80:1752S-8S.
34. Wagner CL, Hulsey TC, Fanning D, Ebeling M, Hollis BW. High-dose vitamin D3 supplementation in a cohort of breastfeeding mothers and their infants: a 6-month follow-up pilot study. Breastfeed Med 2006;1:59-70.