Anti-inflammatory and anti-thrombotic effects of the fungal metabolite galiellalactone in apolipoprotein E-deficient mice

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Bollmann, Franziska ^a   Jäckel, Sven ^a   Schmidtke, Lisa ^a   Schrick, Katharina ^a   Reinhardt, Christoph ^a   Jurk, Kerstin ^a   Wu, Zhixiong ^a   Xia, Ning ^a   Li, Huige ^a   Erkel, Gerhard ^b   Walter, Ulrich ^a   Kleinert, Hartmut ^a   Pautz, Andrea ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b University of Koblenz Landau   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTIINFLAMMATORY AGENT; APOLIPOPROTEIN E; GALIELLALACTONE; INTERLEUKIN 17; INTERLEUKIN 6; OSTEOPONTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; FIBRINOLYTIC AGENT; LACTONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICOAGULATION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASCOMYCETES; BLOOD CLOTTING TIME; CAROTID ARTERY THROMBOSIS; CONTROLLED STUDY; DOWN REGULATION; DRUG DETERMINATION; DRUG ISOLATION; DRUG MECHANISM; DRUG SYNTHESIS; GENE EXPRESSION REGULATION; IL17 GENE; IL6 GENE; IN VIVO STUDY; MOUSE; NONHUMAN; SPP1 GENE; THROMBOCYTE ADHESION; TNF ALPHA GENE; ANIMAL; ATHEROSCLEROSIS; BLOOD CLOTTING; C57BL MOUSE; CAROTID ARTERY; DISEASE MODEL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOOD COAGULATION; CAROTID ARTERIES; CAROTID ARTERY THROMBOSIS; CYTOKINES; DISEASE MODELS, ANIMAL; FIBRINOLYTIC AGENTS; LACTONES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLATELET ADHESIVENESS; WHOLE BLOOD COAGULATION TIME;

EID: 84953855250     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130401     Document Type: Article

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