Upregulating the Expression of Survivin-HBXIP Complex Contributes to the Protective Role of IMM-H004 in Transient Global Cerebral Ischemia/Reperfusion

Molecular Neurobiology

Volumn 54, Issue 1, 2017, Pages 524-540

  Chu, Shi Feng ^a,b   Zhang, Zhao ^b   Zhang, Wei ^b   Zhang, Mei Jin ^b   Gao, Yan ^b   Han, Ning ^b   Zuo, Wei ^b   Huang, Hui Yong ^a   Chen, Nai Hong ^a,b  

^a HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Akt; Delayed neuronal death; Global cerebral ischemia; HBXIP; IMM H004; Neuroprotective role; Survivin

Indexed keywords

BINDING PROTEIN; COUMARIN DERIVATIVE; HEPATITIS B X INTERACTING PROTEIN; IMM H004; NORPHENAZONE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SURVIVIN; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; BIRC5 PROTEIN, RAT; HBXIP PROTEIN, HUMAN; IMM-H004; MICROTUBULE ASSOCIATED PROTEIN; NEUROPROTECTIVE AGENT; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DOSE COMPARISON; HIPPOCAMPAL CA1 REGION; IN VITRO STUDY; IN VIVO STUDY; MALE; NERVE CELL NECROSIS; NONHUMAN; PC12 CELL LINE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION; GENETICS; METABOLISM; PHYSIOLOGY; REPERFUSION INJURY; SPRAGUE DAWLEY RAT; TRANSIENT ISCHEMIC ATTACK; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; COUMARINS; GENE EXPRESSION; ISCHEMIC ATTACK, TRANSIENT; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; UP-REGULATION;

EID: 84953402168     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9673-5     Document Type: Article

References (33)

1. Mehta SL, Manhas N, Raghubir R (2007) Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Res Rev 54:34–66
2. Li Y, Xia ZL, Chen LB (2011) HIF-1-alpha and survivin involved in the anti-apoptotic effect of 2ME2 after global ischemia in rats. Neurol Res 33:583–592
3. Ji HJ, Wang DM, Hu JF, Sun MN, Li G et al (2014) IMM-H004, a novel courmarin derivative, protects against oxygen-and glucose-deprivation/restoration-induced apoptosis in PC12 cells. Eur J Pharmacol 723:259–266
4. Zuo W, Chen J, Zhang S, Tang J, Liu H et al (2014) IMM-H004 prevents toxicity induced by delayed treatment of tPA in a rat model of focal cerebral ischemia involving PKA-and PI3K-dependent Akt activation. Eur J Neurosci 39:2107–2118
5. Zuo W, Zhang W, Han N, Chen NH (2015) Compound IMM-H004, a novel coumarin derivative, protects against CA1 cell loss and spatial learning impairments resulting from transient global ischemia. CNS Neurosci Ther 21:280–288
6. Baratchi S, Kanwar RK, Kanwar JR (2010) Survivin: a target from brain cancer to neurodegenerative disease. Crit Rev Biochem Mol Biol 45:535–554
7. Cheng CW, Chow AK, Pang R, Fok EW, Kwong YL et al (2013) PIN1 inhibits apoptosis in hepatocellular carcinoma through modulation of the antiapoptotic function of survivin. Am J Pathol 182:765–775
8. Jiang Y, de Bruin A, Caldas H, Fangusaro J, Hayes J et al (2005) Essential role for survivin in early brain development. J Neurosci 25:6962–6970
9. Coremans V, Ahmed T, Balschun D, D'Hooge R, DeVriese A et al (2010) Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin. BMC Neurosci 11:2
10. Iscru E, Ahmed T, Coremans V, Bozzi Y, Caleo M et al (2013) Loss of survivin in neural precursor cells results in impaired long-term potentiation in the dentate gyrus and CA1-region. Neuroscience 231:413–419
11. Ambrosini G, Adida C, Altieri DC (1997) A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 3:917–921
12. Conway EM, Zwerts F, Van Eygen V, DeVriese A, Nagai N et al (2003) Survivin-dependent angiogenesis in ischemic brain: molecular mechanisms of hypoxia-induced up-regulation. Am J Pathol 163:935–946
13. Johnson EA, Svetlov SI, Pike BR, Tolentino PJ, Shaw G et al (2004) Cell-specific upregulation of survivin after experimental traumatic brain injury in rats. J Neurotrauma 21:1183–1195
14. Sehara Y, Sawicka K, Hwang JY, Latuszek-Barrantes A, Etgen AM et al (2013) Survivin Is a transcriptional target of STAT3 critical to estradiol neuroprotection in global ischemia. J Neurosci 33:12364–12374
15. Melegari M, Scaglioni PP, Wands JR (1998) Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication. J Virol 72:1737–1743
16. Wang FZ, Sha L, Ye LH, Zhang XD (2008) Promotion of cell proliferation by HBXIP via upregulation of human telomerase reverse transcriptase in human mesenchymal stem cells. Acta Pharmacol Sin 29:83–89
17. Wang FZ, Sha L, Zhang WY, Wu LY, Qiao L et al (2007) Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells. Acta Pharmacol Sin 28:431–438
18. Zangemeister-Wittke U, Simon HU (2004) An IAP in action: the multiple roles of survivin in differentiation, immunity and malignancy. Cell Cycle 3:1121–1123
19. Liu S, Li L, Zhang Y, Zhang Y, Zhao Y et al (2012) The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells. J Biol Chem 287:30228–30239
20. Liu F, You X, Wang Y, Liu Q, Liu Y et al (2014) The oncoprotein HBXIP enhances angiogenesis and growth of breast cancer through modulating FGF8 and VEGF. Carcinogenesis 35:1144–1153
21. Wang F, Fei H, Qi B, Yao S, Chang Z (2012) Overexpression of hepatitis B x-interacting protein in HepG2 cells enhances tumor-induced angiogenesis. Mol Cell Biochem 364:165–171
22. Pulsinelli WA, Brierley JB (1979) A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10:267–272
23. Tanaka S, Uehara T, Nomura Y (2000) Up-regulation of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death. J Biol Chem 275:10388–10393
24. Sun LN, Shen J, Su F, Wang Q, Zhu YJ et al (2009) Bicyclol attenuates oxidative stress and neuronal damage following transient forebrain ischemia in mouse cortex and hippocampus. Neurosci Lett 459:84–87
25. Jiao L, Zhang J, Li Z, Liu H, Chen Y et al (2011) Edaravone alleviates delayed neuronal death and long-dated cognitive dysfunction of hippocampus after transient focal ischemia in Wistar rat brains. Neuroscience 182:177–183
26. Tu XK, Yang WZ, Chen JP, Chen Y, Chen Q, et al. (2014) Repetitive Ischemic Preconditioning Attenuates Inflammatory Reaction and Brain Damage After Focal Cerebral Ischemia in Rats: Involvement of PI3K/Akt and ERK1/2 Signaling Pathway. J Mol Neurosci 55:912–922
27. Guha M, Plescia J, Leav I, Li J, Languino LR et al (2009) Endogenous tumor suppression mediated by PTEN involves survivin gene silencing. Cancer Res 69:4954–4958
28. Kirino T (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 239:57–69
29. Kirino T, Tamura A, Sano K (1984) Delayed neuronal death in the rat hippocampus following transient forebrain ischemia. Acta Neuropathol 64:139–147
30. Cervos-Navarro J, Diemer NH (1991) Selective vulnerability in brain hypoxia. Crit Rev Neurobiol 6:149–182
31. Du C, Fang M, Li Y, Li L, Wang X (2000) Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102:33–42
32. Zhong Q, Zhou Y, Ye W, Cai T, Zhang X et al (2012) Hypoxia-inducible factor 1-alpha-AA-modified bone marrow stem cells protect PC12 cells from hypoxia-induced apoptosis, partially through VEGF/PI3K/Akt/FoxO1 pathway. Stem Cells Dev 21:2703–2717
33. Chan WY, Xia CL, Dong DC, Heizmann CW, Yew DT (2003) Differential expression of S100 proteins in the developing human hippocampus and temporal cortex. Microsc Res Tech 60:600–613