High-Mannose Specific Lectin and Its Recombinants from a Carrageenophyta Kappaphycus alvarezii Represent a Potent Anti-HIV Activity Through High-Affinity Binding to the Viral Envelope Glycoprotein gp120

Marine Biotechnology

Volumn 18, Issue 1, 2016, Pages 144-160

  Hirayama, Makoto ^a   Shibata, Hiromi ^a   Imamura, Koji ^b   Sakaguchi, Takemasa ^a   Hori, Kanji ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b Medical & Biological Laboratories Co Ltd   (Japan)

Author keywords

Alga; Antiviral lectin; Carageenophyta; HIV; Kappaphycus alvarezii

Indexed keywords

ALGAE; ASSOCIATION REACTIONS; BINS; DISEASES; DNA SEQUENCES; ESCHERICHIA COLI; GALLIUM ALLOYS; GLYCOPROTEINS; OLIGOSACCHARIDES; POLYSACCHARIDES; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE; VIRUSES;

ANTIVIRAL LECTIN; CARAGEENOPHYTA; ENVELOPE GLYCOPROTEINS; ESCHERICHIA COLI EXPRESSION SYSTEMS; HIV; KAPPAPHYCUS ALVAREZII; MANNOSE BINDING LECTINS; OLIGOSACCHARIDE BINDINGS;

PROTEINS;

DNA; HUMAN IMMUNODEFICIENCY VIRUS; PEPTIDE; PROTEIN; RED ALGA;

ALGAE; ESCHERICHIA COLI; EUCHEUMA SERRA; HUMAN IMMUNODEFICIENCY VIRUS 1; KAPPAPHYCUS ALVAREZII; ORTHOMYXOVIRIDAE; PLANKTOTHRIX AGARDHII; RHODOPHYTA;

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; GLYCOPROTEIN GP 120; MANNOSE BINDING LECTIN; PROTEIN BINDING; RECOMBINANT PROTEIN;

BINDING SITE; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS; METABOLISM; PHYSIOLOGY; PROCEDURES; PROTEIN ENGINEERING; RED ALGA; VIRUS ENTRY;

ANTI-HIV AGENTS; BINDING SITES; HIV; HIV ENVELOPE PROTEIN GP120; MANNOSE-BINDING LECTINS; PROTEIN BINDING; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; RHODOPHYTA; VIRUS INTERNALIZATION;

EID: 84953354249     PISSN: 14362228     EISSN: 14362236     Source Type: Journal    
DOI: 10.1007/s10126-015-9677-1     Document Type: Article

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