Apoptosis Induced by Microbubble-Assisted Acoustic Cavitation in K562 Cells: The Predominant Role of the Cyclosporin A-Dependent Mitochondrial Permeability Transition Pore

Ultrasound in Medicine and Biology

Volumn 41, Issue 10, 2015, Pages 2755-2764

  Zhao, Lu ^a   Feng, Yi ^a   Shi, Aiwei ^a   Zong, Yujin ^a   Wan, Mingxi ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Acoustic cavitation; Cyclosporin A; Cytochrome c; Microbubble; Mitochondrial permeability transition pore

Indexed keywords

CAVITATION; CELL DEATH; CELL MEMBRANES; CELLS; CYTOLOGY; MOBILE SECURITY; PROTEINS; ULTRASONICS;

ACOUSTIC CAVITATIONS; CYCLOSPORIN A; CYTOCHROME C; MICRO-BUBBLE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE;

MITOCHONDRIA;

BAX INHIBITING PEPTIDE; CYCLOSPORIN A; CYTOCHROME C; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; CARRIER PROTEIN; CYCLOSPORIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ECHOGRAPHY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INHIBITION KINETICS; K562 CELL LINE; MEMBRANE DEPOLARIZATION; MICROBUBBLE; MICROBUBBLE ASSISTED ACOUSTIC CAVITATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; ONCOLOGICAL PROCEDURE; PRIORITY JOURNAL; PROTEIN SECRETION; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; DOSE RESPONSE; METABOLISM; NEOPLASMS, EXPERIMENTAL; PATHOLOGY; PROCEDURES; RADIATION DOSE; RADIATION RESPONSE; SOUND; THERAPEUTIC USE; ULTRASOUND; ULTRASOUND THERAPY;

APOPTOSIS; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; K562 CELLS; MICROBUBBLES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; NEOPLASMS, EXPERIMENTAL; RADIATION DOSAGE; SONICATION; SOUND; ULTRASONIC THERAPY;

EID: 84953345957     PISSN: 03015629     EISSN: 1879291X     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2015.05.021     Document Type: Article

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