Temperature-dependent acetoin production by Pyrococcus furiosus is catalyzed by a biosynthetic acetolactate synthase and its deletion improves ethanol production

Metabolic Engineering

Volumn 34, Issue , 2016, Pages 71-79

  Nguyen, Diep M N ^a   Lipscomb, Gina L ^a   Schut, Gerrit J ^a   Vaccaro, Brian J ^a   Basen, Mirko ^a,c   Kelly, Robert M ^b   Adams, Michael W W ^a  

^a University of Georgia   (United States)

^b North Carolina State University   (United States)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

Acetoin; Acetolactate synthase; Archaea; Ethanol; Genetic engineering; Hyperthermophile

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CARBON; CARBON DIOXIDE; GENES; GENETIC ENGINEERING; METABOLISM; MICROORGANISMS;

ACETOIN; ACETOLACTATE SYNTHASE; ARCHAEA; BIOLOGICAL PRODUCTION; BRANCHED CHAIN AMINO ACIDS; HYPERTHERMOPHILES; HYPERTHERMOPHILIC ARCHAEON; TEMPERATURE DEPENDENT;

ETHANOL;

ACETIC ACID; ACETOIN; ACETOLACTATE SYNTHASE; ALCOHOL; AMINO ACID; BIOFUEL; CARBOHYDRATE; CARBON DIOXIDE; HYDROGEN;

ALCOHOL PRODUCTION; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BIOSYNTHESIS; CATALYSIS; CELL SUSPENSION; CONTROLLED STUDY; LOW TEMPERATURE; METABOLITE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PYROCOCCUS FURIOSUS; TEMPERATURE DEPENDENCE; GENE DELETION; GENETIC ENHANCEMENT; GENETICS; ISOLATION AND PURIFICATION; METABOLIC ENGINEERING; METABOLISM; PHYSIOLOGY; PROCEDURES; TEMPERATURE;

ACETOIN; ACETOLACTATE SYNTHASE; CATALYSIS; ETHANOL; GENE DELETION; GENETIC ENHANCEMENT; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; PYROCOCCUS FURIOSUS; TEMPERATURE;

EID: 84953266302     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.12.006     Document Type: Article

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