Releasing Nrf2 to promote neurite outgrowth

Neural Regeneration Research

Volumn 10, Issue 12, 2015, Pages 1934-1935

  Yang, Chuanbin ^a   Cheng, Yuanyuan ^a   Zhao, Jiao ^a   Rong, Jianhui ^a  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE DERIVATIVE; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; N PROPARGYL CAFFEATE AMIDE; OXIDOPAMINE; PROTOPORPHYRIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ARTICLE; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NEUROLOGIC DISEASE; NEUROPROTECTION; PROTEIN EXPRESSION;

EID: 84953253517     PISSN: 16735374     EISSN: 18767958     Source Type: Journal    
DOI: 10.4103/1673-5374.169618     Document Type: Article

References (28)

1. Abdipranoto A, Wu S, Stayte S, Vissel B (2008) The role of neurogenesis in neurodegenerative diseases and its implications for therapeutic development. CNS Neurol Disord Drug Targets 7:187-210
2. Allen SJ, Watson JJ, Shoemark DK, Barua NU, Patel NK (2013) GDNF, NGF and BDNF as therapeutic options for neurodegeneration. Pharmacol Ther 138:155-175
3. Ataie A, Sabetkasaei M, Haghparast A, Moghaddam AH, Kazeminejad B (2010) Neuroprotective effects of the polyphenolic antioxidant agent, Curcumin, against homocysteine-induced cognitive impairment and oxidative stress in the rat. Pharmacol Biochem Behav 96:378-385
4. Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD (2005) Modifying pecific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt inding to the Nrf2 domain Neh2. Proc Natl Acad Sci U S A 102:10070-10075
5. Gordon CG, Mackey JL, Jewett JC, Sletten EM, Houk K, Bertozzi CR (2012) Reactivity f biarylazacyclooctynones in copper-free click chemistry. J Am Chem Soc 134:9199-208
6. Hennigan A, O’callaghan R, Kelly A (2007) Neurotrophins and their receptors:roles in lasticity, neurodegeneration and neuroprotection. Biochem Soc Trans 35:424-427
7. Ho YS, Chun-Hei Poon D, Chan TF, Chuen-Chung Chang R (2012) From small to big molecules: how do we prevent and delay the progression of age-related neurodegeneration? Curr Pharm Des 18:15-26
8. Jin K, Galvan V, Xie L, Mao XO, Gorostiza OF, Bredesen DE, Greenberg DA (2004) Enhanced neurogenesis in Alzheimer’s disease transgenic (PDGFAPPSw, Ind) mice. Proc Natl Acad Sci U S A 101:13363-13367
9. Joshi G, Johnson JA (2012) The Nrf2-ARE pathway: a valuable therapeutictarget for the treatment of neurodegenerative diseases. Recent Pat CNSDrug Discov 7:218-229
10. Kärkkäinen V, Pomeshchik Y, Savchenko E, Dhungana H, Kurronen A, Lehtonen S, Naumenko N, Tavi P, Levonen AL, Yamamoto M (2014) Nrf2 regulatesneurogenesis and protects neural progenitor cells against Aβ toxicity. Stem Cells 32:1904-1916
11. Ma Q (2013) Role of Nrf2 in oxidative stress and toxicity. Annu Rev PharmacolToxicol 53:401-426
12. McKay CS, Finn M (2014) Click chemistry in complex mixtures: Bioorthogonal bioconjugation. Chem Biol 21:1075-1101
13. Motterlini R, Foresti R (2014) Heme oxygenase-1 as a target for drug discovery. Antioxid Redox Signal 20:1810-1826
14. Price RD, Milne SA, Sharkey J, Matsuoka N (2007) Advances in small moleculespromoting neurotrophic function. Pharmacol Ther 115:292-306
15. Qi H, Han Y, Rong J (2012) Potential roles of PI3K/Akt and Nrf2–Keap1pathways in regulating hormesis of Z-ligustilide in PC12 cells against oxygenand glucose deprivation. Neuropharmacology 62:1659-1670
16. Scapagnini G, Sonya V, Nader AG, Calogero C, Zella D, Fabio G (2011) Modulation of Nrf2/ARE pathway by food polyphenols: a nutritional neuroprotectivestrategy for cognitive and neurodegenerative disorders. MolNeurobiol 44:192-201
17. Shi H, Xie D, Yang R, Cheng Y (2014) Synthesis of caffeic acid phenethyl esterderivatives, and their cytoprotective and neuritogenic activities in PC12cells. J Agric Food Chem 62:5046-5053
18. Silva T, Oliveira C, Borges F (2014) Caffeic acid derivatives, analogs and applications:a patent review (2009-2013). Expert Opin Ther Pat 24:1257-1270
19. Spedding M, Gressens P (2008) Neurotrophins and cytokines in neuronalplasticity. In: Novartis Foundation Symposium, p 222: Chichester; NewYork; John Wiley; 1999
20. Tolba MF, Azab SS, Khalifa AE, Abdel-Rahman SZ, Abdel-Naim AB (2013) Caffeic acid phenethyl ester, a promising component of propolis with aplethora of biological activities: A review on its anti‐inflammatory, neuroprotective, hepatoprotective, and cardioprotective effects. IUBMB Life 65:699-709
21. Wahlang B, Falkner KC, Cave MC, Prough RA (2015) Role of cytochromeP450 monooxygenase in carcinogen and chemotherapeutic drug metabolism. Adv Pharmacol 74:1-33
22. Wakabayashi N, Shin S, Slocum SL, Agoston ES, Wakabayashi J, Kwak MK, Misra V, Biswal S, Yamamoto M, Kensler TW (2010) Regulation of notch1signaling by Nrf2: implications for tissue regeneration. Sci Signal 3: ra52
23. Winner B, Kohl Z, Gage FH (2011) Neurodegenerative disease and adult neurogenesis. Eur J Neurosci 33:1139-1151
24. Yang C, Zhao J, Pei W, Zheng X, Rong J (2014a) Biochemical mechanisms ofbornyl caffeate induced cytotoxicity in rat pheochromocytoma PC12 cells. Chem Biol Interact 219:133-142
25. Yang C, Zhao J, Cheng Y, Le XC, Rong J (2015) N-propargyl caffeate amide(PACA) potentiates nerve growth factor (NGF)-induced neurite outgrowthand attenuates 6-hydroxydopamine (6-OHDA)-induced toxicity by activatingthe Nrf2/HO-1 pathway. ACS Chem Neurosci 6:1560-1569
26. Yang CB, Pei WJ, Zhao J, Cheng YY, Zheng XH, Rong JH (2014b) Bornyl caffeateinduces apoptosis in human breast cancer MCF-7 cells via the ROSandJNK-mediated pathways. Acta Pharmacol Sin 35:113-123
27. Zhang DD (2006) Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metabol Rev 38:769-789
28. Zhao F, Wu T, Lau A, Jiang T, Huang Z, Wang XJ, Chen W, Wong PK, Zhang DD (2009) Nrf2 promotes neuronal cell differentiation. Free Radic BiolMed 47:867-879.