Different gastric microbiota compositions in two human populations with high and low gastric cancer risk in Colombia

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Yang, Ines ^a,b   Woltemate, Sabrina ^a,b   Piazuelo, M Blanca ^c   Bravo, Luis E ^d   Yepez, Maria Clara ^e   Romero Gallo, Judith ^c   Delgado, Alberto G ^c   Wilson, Keith T ^c,f,g   Peek, Richard M ^c,f   Correa, Pelayo ^c   Josenhans, Christine ^a,b   Fox, James G ^h   Suerbaum, Sebastian ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Center for Experimental and Clinical Infection Research   (Germany)

^c VANDERBILT UNIVERSITY   (United States)

^d UNIVERSIDAD DEL VALLE   (Colombia)

^e UNIVERSIDAD DE NARIÑO   (Colombia)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

^h MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; COLOMBIA; COMPLICATION; FEMALE; GENETICS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MALE; METAGENOME; METAGENOMICS; MICROBIOLOGY; MICROFLORA; MIDDLE AGED; RISK; STOMACH; STOMACH NEOPLASMS;

ADULT; COLOMBIA; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; METAGENOME; METAGENOMICS; MICROBIOTA; MIDDLE AGED; RISK; STOMACH; STOMACH NEOPLASMS;

EID: 84953246963     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18594     Document Type: Article

References (50)

1. IARC Helicobacter pylori Working Group. Helicobacter pylori eradication as a strategy for preventing gastric cancer. 8, (International Agency for Research on Cancer, 2014).
2. Correa, P. & Piazuelo, M. B. Gastric cancer: The Colombian enigma. Rev. Colomb. Gastroenterol. 25, 334-337 (2010).
3. Whary, M. T. et al. Intestinal helminthiasis in Colombian children promotes a Th2 response to Helicobacter pylori: Possible implications for gastric carcinogenesis. Cancer Epidemiol. Biomark. Prev. Publ. Am. Assoc. Cancer Res. Cosponsored Am. Soc. Prev. Oncol. 14, 1464-1469 (2005).
4. Camargo, M. C. et al. Plasma selenium measurements in subjects from areas with contrasting gastric cancer risks in Colombia. Arch. Med. Res. 39, 443-451 (2008).
5. Torres, J. et al. Gastric cancer incidence and mortality is associated with altitude in the mountainous regions of Pacific Latin America. Cancer Causes Control CCC 24, 249-256 (2013).
6. Bravo, L. E., van Doom, L.-J., Realpe, J. L. & Correa, P. Virulence-associated genotypes of Helicobacter pylori: Do they explain the African enigma? Am. J. Gastroenterol. 97, 2839-2842 (2002).
7. Fox, J. G. et al. Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy. Nat. Med. 6, 536-542 (2000).
8. Whary, M. T. et al. Helminth co-infection in Helicobacter pylori infected INS-GAS mice attenuates gastric premalignant lesions of epithelial dysplasia and glandular atrophy and preserves colonization resistance of the stomach to lower bowel microbiota. Microbes Infect. Inst. Pasteur 16, 345-355 (2014).
9. Kodaman, N. et al. Human and Helicobacter pylori coevolution shapes the risk of gastric disease. Proc. Natl. Acad. Sci. USA. 111, 1455-1460 (2014).
10. Lofgren, J. L. et al. Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia. Gastroenterology 140, 210-220 (2011).
11. Lertpiriyapong, K. et al. Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis. Gut 63, 54-63 (2014).
12. White, J. R., Nagarajan, N. & Pop, M. Statistical methods for detecting differentially abundant features in clinical metagenomic samples. PLoS Comput. Biol. 5, e1000352 (2009).
13. Russo, F., Linsalata, M. & Orlando, A. Probiotics against neoplastic transformation of gastric mucosa: Effects on cell proliferation and polyamine metabolism. World J. Gastroenterol. WJG 20, 13258-13272 (2014).
14. Lundberg, J. O. & Weitzberg, E. Biology of nitrogen oxides in the gastrointestinal tract. Gut 62, 616-629 (2013).
15. Hsieh, P.-S. et al. Eradication of Helicobacter pylori infection by the probiotic strains Lactobacillus johnsonii MH-68 and "L. salivarius ssp. salicinius AP-32. Helicobacter 17, 466-477 (2012).
16. Thiraworawong, T. et al. Anti-inflammatory properties of gastric-derived Lactobacillus plantarum XB7 in the context of Helicobacter pylori infection. Helicobacter 19, 144-155 (2014).
17. Ge, Z. et al. Coinfection with enterohepatic Helicobacter species can ameliorate or promote Helicobacter pylori-induced gastric pathology in C57BL/6 mice. Infect. Immun. 79, 3861-3871 (2011).
18. Lemke, L. B. et al. Concurrent Helicobacter bilis infection in C57BL/6 mice attenuates proinflammatory H. pylori-induced gastric pathology. Infect. Immun. 77, 2147-2158 (2009).
19. Dharmani, P., De Simone, C. & Chadee, K. The probiotic mixture VSL#3 accelerates gastric ulcer healing by stimulating vascular endothelial growth factor. PloS One 8, e58671 (2013).
20. Delgado, S., Leite, A. M. O., Ruas-Madiedo, P. & Mayo, B. Probiotic and technological properties of Lactobacillus spp. strains from the human stomach in the search for potential candidates against gastric microbial dysbiosis. Front. Microbiol. 5, 766 (2015).
21. Arthur, J. C. et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 338, 120-123 (2012).
22. Osaki, T. et al. Comparative analysis of gastric bacterial microbiota in Mongolian gerbils after long-term infection with Helicobacter pylori. Microb. Pathog. 53, 12-18 (2012).
23. Sharma, B. K. et al. Intragastric bacterial activity and nitrosation before, during, and after treatment with omeprazole. Br. Med. J. Clin. Res. Ed 289, 717-719 (1984).
24. Bik, E. M. et al. Molecular analysis of the bacterial microbiota in the human stomach. Proc. Natl. Acad. Sci. USA. 103, 732-737 (2006).
25. Kato, S. et al. Non-Helicobacter bacterial flora rarely develops in the gastric mucosal layer of children. Dig. Dis. Sci. 51, 641-646 (2006).
26. Andersson, A. F. et al. Comparative analysis of human gut microbiota by barcoded pyrosequencing. PloS One 3, e2836 (2008).
27. Dicksved, J. et al. Molecular characterization of the stomach microbiota in patients with gastric cancer and in controls. J. Med. Microbiol. 58, 509-516 (2009).
28. Li, X.-X. et al. Bacterial microbiota profiling in gastritis without Helicobacter pylori infection or non-steroidal anti-inflammatory drug use. PloS One 4, e7985 (2009).
29. Stearns, J. C. et al. Bacterial biogeography of the human digestive tract. Sci. Rep. 1, (2011).
30. Hu, Y. et al. Bacterial flora concurrent with Helicobacter pylori in the stomach of patients with upper gastrointestinal diseases. World J. Gastroenterol. WJG 18, 1257-1261 (2012).
31. Delgado, S., Cabrera-Rubio, R., Mira, A., Suárez, A. & Mayo, B. Microbiological survey of the human gastric ecosystem using culturing and pyrosequencing methods. Microb. Ecol. 65, 763-772 (2013).
32. von Rosenvinge, E. C. et al. Immune status, antibiotic medication and pH are associated with changes in the stomach fluid microbiota. ISME J. 7, 1354-1366 (2013).
33. Khosravi, Y. et al. Culturable bacterial microbiota of the stomach of Helicobacter pylori positive and negative gastric disease patients. ScientificWorldJournal 2014, 610421 (2014).
34. Couturier, M. R., Slechta, E. S., Goulston, C., Fisher, M. A. & Hanson, K. E. Leptotrichia bacteremia in patients receiving high-dose chemotherapy. J. Clin. Microbiol. 50, 1228-1232 (2012).
35. Riggio, M. P. et al. Molecular identification of bacteria on the tongue dorsum of subjects with and without halitosis. Oral Dis. 14, 251-258 (2008).
36. Chen, T. et al. The Human Oral Microbiome Database: A web accessible resource for investigating oral microbe taxonomic and genomic information. Database J. Biol. Databases Curation 2010, baq013 (2010).
37. Hsiao, W. W. et al. Microbial transformation from normal oral microbiota to acute endodontic infections. BMC Genomics 13, 345 (2012).
38. Helsel, L. O. et al. Identification of 'Haematobacter', a new genus of aerobic Gram-negative rods isolated from clinical specimens, and reclassification of Rhodobacter massiliensis as 'Haematobacter massiliensis comb. nov.' J. Clin. Microbiol. 45, 1238-1243 (2007).
39. Buscher, A., Li, L., Han, X. Y. & Trautner, B. W. Aortic valve endocarditis possibly caused by a Haematobacter-like species. J. Clin. Microbiol. 48, 3791-3793 (2010).
40. The Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 486, 207-214 (2012).
41. Zilberstein, B. et al. Digestive tract microbiota in healthy volunteers. Clin. São Paulo Braz. 62, 47-54 (2007).
42. Huse, S. M., Ye, Y., Zhou, Y. & Fodor, A. A. A core human microbiome as viewed through 16S rRNA sequence clusters. PloS One 7, e34242 (2012).
43. Liu, B. et al. Deep sequencing of the oral microbiome reveals signatures of periodontal disease. PloS One 7, e37919 (2012).
44. Shaddox, L. M. et al. Microbiological characterization in children with aggressive periodontitis. J. Dent. Res. 91, 927-933 (2012).
45. Xie, C.-H. & Yokota, A. Reclassification of Alcaligenes latus strains IAM 12599T and IAM 12664 and Pseudomonas saccharophila as Azohydromonas lata gen. nov., comb. nov., Azohydromonas australica sp. nov. and Pelomonas saccharophila gen. nov., comb. nov., respectively. Int. J. Syst. Evol. Microbiol. 55, 2419-2425 (2005).
46. Gomila, M., Bowien, B., Falsen, E., Moore, E. R. B. & Lalucat, J. Description of Pelomonas aquatica sp. nov. and Pelomonas puraquae sp. nov., isolated from industrial and haemodialysis water. Int. J. Syst. Evol. Microbiol. 57, 2629-2635 (2007).
47. Pérez-Chaparro, P. J. et al. Newly identified pathogens associated with periodontitis: A systematic review. J. Dent. Res. 93, 846-858 (2014).
48. Aviles-Jimenez, F., Vazquez-Jimenez, F., Medrano-Guzman, R., Mantilla, A. & Torres, J. Stomach microbiota composition varies between patients with non-atrophic gastritis and patients with intestinal type of gastric cancer. Sci. Rep. 4, 4202 (2014).
49. de Sablet, T. et al. Phylogeographic origin of Helicobacter pylori is a determinant of gastric cancer risk. Gut 60, 1189-1195 (2011).
50. Yang, I. et al. Intestinal microbiota composition of interleukin-10 deficient C57BL/6J mice and susceptibility to Helicobacter hepaticusinduced colitis. PLoS ONE 8, e70783 (2013).