Valproic Acid Enhances iPSC Induction From Human Bone Marrow-Derived Cells Through the Suppression of Reprogramming-Induced Senescence

Journal of Cellular Physiology

Volumn 231, Issue 8, 2016, Pages 1719-1727

  Chen, Xi ^a,b   Zhai, Yingying ^a,b   Yu, Dehai ^a,b   Cui, Jiuwei ^a   Hu, Ji Fan ^a,b   Li, Wei ^a  

^a JILIN UNIVERSITY   (China)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KRUPPEL LIKE FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN P16; PROTEIN P21; RNA; TRANSCRIPTION FACTOR SOX2; VALPROIC ACID; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE DEACETYLASE INHIBITOR; TRANSCRIPTION FACTOR;

ARTICLE; BONE MARROW SUPPRESSION; CELL PROLIFERATION; CELL STRESS; CONTROLLED STUDY; DONOR; DOWN REGULATION; G2 PHASE CELL CYCLE CHECKPOINT; GENE ACTIVATION; GENE INDUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LENTIVIRINAE; MALE; NORMAL HUMAN; NUCLEAR REPROGRAMMING; ONCOGENE C MYC; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SENESCENCE; BONE MARROW CELL; CELL AGING; CELL LINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PHENOTYPE;

BONE MARROW CELLS; CELL AGING; CELL LINE; CELL PROLIFERATION; CELLULAR REPROGRAMMING; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC VECTORS; HISTONE DEACETYLASE INHIBITORS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LENTIVIRUS; PHENOTYPE; TRANSCRIPTION FACTORS; TRANSFECTION; VALPROIC ACID;

EID: 84952918891     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.25270     Document Type: Article

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