Effects of doxycycline on local and systemic inflammation in stable COPD patients, a randomized clinical trial

Respiratory Medicine

Volumn 110, Issue , 2016, Pages 46-52

  Prins, Hendrik J ^a   Daniels, Johannes M A ^b   Lindeman, Jan H ^c   Lutter, René ^d   Boersma, Wim G ^a  

^a Medical Centre Alkmaar   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Anti inflammatory effect; COPD; Doxycycline; Inflammation

Indexed keywords

C REACTIVE PROTEIN; DOXYCYCLINE; GELATINASE B; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MATRIX METALLOPROTEINASE; MYELOPEROXIDASE; NEUTROPHIL COLLAGENASE; PLACEBO; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; ANTIINFECTIVE AGENT; AUTACOID; CYTOKINE;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; INFLAMMATION; MALE; NEUTROPHIL MEDIATED INFLAMMATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SPUTUM; SPUTUM CULTURE; DRUG EFFECTS; METABOLISM; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

AGED; ANTI-BACTERIAL AGENTS; C-REACTIVE PROTEIN; CYTOKINES; DOUBLE-BLIND METHOD; DOXYCYCLINE; FEMALE; HUMANS; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SPUTUM;

EID: 84952871007     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2015.10.009     Document Type: Article

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