Regulation of mitochondrial oxidative stress by β-Arrestins in cultured human cardiac fibroblasts

DMM Disease Models and Mechanisms

Volumn 8, Issue 12, 2015, Pages 1579-1589

  Philip, Jennifer L ^a   Razzaque, Md Abdur ^a   Han, Mei ^a   Li, Jinju ^b   Theccanat, Tiju ^b   Xu, Xianyao ^a   Akhter, Shahab A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

Cardiac fibroblast; Collagen; Heart failure; Myocardial fibrosis; NADPH oxidase; Oxidative stress; arrestin

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA ARRESTIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; SUPEROXIDE; TRANSFORMING GROWTH FACTOR BETA; COLLAGEN; MITOGEN ACTIVATED PROTEIN KINASE; NOX4 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RETINA S ANTIGEN;

ADULT; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENE OVEREXPRESSION; HEART FAILURE; HEART FIBROBLAST; HEART LEFT VENTRICLE; HEART MUSCLE FIBROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; INVESTIGATIVE PROCEDURES; MITOCHONDRION; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; BIOSYNTHESIS; CARDIAC MUSCLE; DRUG EFFECTS; ENZYMOLOGY; FIBROBLAST; METABOLISM; MYOFIBROBLAST; PATHOLOGY; TRANSFORMED CELL LINE;

ARRESTINS; BETA-ARRESTINS; CELL LINE, TRANSFORMED; CELLS, CULTURED; COLLAGEN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HEART FAILURE; HUMANS; MITOCHONDRIA; MYOCARDIUM; MYOFIBROBLASTS; NADPH OXIDASE; OXIDATIVE STRESS; SUPEROXIDES; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84952815434     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.019968     Document Type: Article

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