메뉴 건너뛰기




Volumn 6, Issue 6, 2015, Pages

Transcriptomic analysis of chronic hepatitis b and c and liver cancer reveals microrna-mediated control of cholesterol synthesis programs

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MESSENGER RNA; MICRORNA; MICRORNA 1307; MICRORNA 21; MICRORNA 224; MICRORNA 27; MICRORNA 33; UNCLASSIFIED DRUG; CHOLESTEROL; GENETIC MARKER;

EID: 84952803164     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01500-15     Document Type: Article
Times cited : (38)

References (59)
  • 1
    • 84873020277 scopus 로고    scopus 로고
    • Pathogenic mechanisms in HBV-and HCV-associated hepatocellular carcinoma
    • Arzumanyan A, Reis HMGPV, Feitelson MA. 2013. Pathogenic mechanisms in HBV-and HCV-associated hepatocellular carcinoma. Nat Rev Cancer 13:123-135. http://dx.doi.org/10.1038/nrc3449.
    • (2013) Nat Rev Cancer , vol.13 , pp. 123-135
    • Arzumanyan, A.1    Reis, H.M.G.P.V.2    Feitelson, M.A.3
  • 3
    • 70350044610 scopus 로고    scopus 로고
    • Hepatitis C virus infection and its clearance alter circulating lipids: Implications for long-term follow-up
    • Corey KE, Kane E, Munroe C, Barlow LL, Zheng H, Chung RT. 2009. Hepatitis C virus infection and its clearance alter circulating lipids: implications for long-term follow-up. Hepatology 50:1030-1037. http:// dx.doi.org/10.1002/hep.23219.
    • (2009) Hepatology , vol.50 , pp. 1030-1037
    • Corey, K.E.1    Kane, E.2    Munroe, C.3    Barlow, L.L.4    Zheng, H.5    Chung, R.T.6
  • 4
    • 0027408923 scopus 로고
    • Prolonged infection with hepatitis B virus and association between low blood cholesterol concentration and liver cancer
    • Chen Z, Keech A, Collins R, Slavin B, Chen J, Campbell TC, Peto R. 1993. Prolonged infection with hepatitis B virus and association between low blood cholesterol concentration and liver cancer. BMJ 306:890-894. http://dx.doi.org/10.1136/bmj.306.6882.890.
    • (1993) BMJ , vol.306 , pp. 890-894
    • Chen, Z.1    Keech, A.2    Collins, R.3    Slavin, B.4    Chen, J.5    Campbell, T.C.6    Peto, R.7
  • 5
    • 84878184684 scopus 로고    scopus 로고
    • Hepatitis C virus, cholesterol and lipoproteins-impact for the viral life cycle and pathogenesis of liver disease
    • Felmlee DJ, Hafirassou ML, Lefevre M, Baumert TF, Schuster C. 2013. Hepatitis C virus, cholesterol and lipoproteins-impact for the viral life cycle and pathogenesis of liver disease. Viruses 5:1292-1324. http:// dx.doi.org/10.3390/v5051292.
    • (2013) Viruses , vol.5 , pp. 1292-1324
    • Felmlee, D.J.1    Hafirassou, M.L.2    Lefevre, M.3    Baumert, T.F.4    Schuster, C.5
  • 6
    • 33646372714 scopus 로고    scopus 로고
    • Influence of liver cancer on lipid and lipoprotein metabolism
    • Jiang J, Nilsson-Ehle P, Xu N. 2006. Influence of liver cancer on lipid and lipoprotein metabolism. Lipids Health Dis 5:4. http://dx.doi.org/10.1186/ 1476-511X-5-4.
    • (2006) Lipids Health Dis , vol.5 , pp. 4
    • Jiang, J.1    Nilsson-Ehle, P.2    Xu, N.3
  • 8
    • 84887602906 scopus 로고    scopus 로고
    • HCV and host lipids: An intimate connection
    • Schaefer EA, Chung RT. 2013. HCV and host lipids: an intimate connection. Semin Liver Dis 33:358-368. http://dx.doi.org/10.1055/s-0033-1358524.
    • (2013) Semin Liver Dis , vol.33 , pp. 358-368
    • Schaefer, E.A.1    Chung, R.T.2
  • 10
    • 84870909543 scopus 로고    scopus 로고
    • MicroRNA regulation of lipid metabolism
    • Flowers E, Froelicher ES, Aouizerat BE. 2013. MicroRNA regulation of lipid metabolism. Metab Clin Exp 62:12-20. http://dx.doi.org/10.1016/ j.metabol.2012.04.009.
    • (2013) Metab Clin Exp , vol.62 , pp. 12-20
    • Flowers, E.1    Froelicher, E.S.2    Aouizerat, B.E.3
  • 11
    • 84876812092 scopus 로고    scopus 로고
    • Complexity of microRNA function and the role of isomiRs in lipid homeostasis
    • Vickers KC, Sethupathy P, Baran-Gale J, Remaley AT. 2013. Complexity of microRNA function and the role of isomiRs in lipid homeostasis. J Lipids Res 54:1182-1191. http://dx.doi.org/10.1194/jlr.R034801.
    • (2013) J Lipids Res , vol.54 , pp. 1182-1191
    • Vickers, K.C.1    Sethupathy, P.2    Baran-Gale, J.3    Remaley, A.T.4
  • 13
    • 24644483623 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA
    • Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P. 2005. Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA. Science 309:1577-1581. http://dx.doi.org/10.1126/science.1113329.
    • (2005) Science , vol.309 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3    Lemon, S.M.4    Sarnow, P.5
  • 14
    • 84888131014 scopus 로고    scopus 로고
    • Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT
    • Choi SE, Fu T, Seok S, Kim DH, Yu E, Lee KW, Kang Y, Li X, Kemper B, Kemper JK. 2013. Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT. Aging Cell 12: 1062-1072. http://dx.doi.org/10.1111/acel.12135.
    • (2013) Aging Cell , vol.12 , pp. 1062-1072
    • Choi, S.E.1    Fu, T.2    Seok, S.3    Kim, D.H.4    Yu, E.5    Lee, K.W.6    Kang, Y.7    Li, X.8    Kemper, B.9    Kemper, J.K.10
  • 16
    • 77955456415 scopus 로고    scopus 로고
    • miR-33 links SREBP-2 induction to repression of sterol transporters
    • Marquart TJ, Allen RM, Ory DS, Baldan A. 2010. miR-33 links SREBP-2 induction to repression of sterol transporters. Proc Natl Acad Sci U S A 107:12228-12232. http://dx.doi.org/10.1073/pnas.1005191107.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 12228-12232
    • Marquart, T.J.1    Allen, R.M.2    Ory, D.S.3    Baldan, A.4
  • 17
    • 77953780835 scopus 로고    scopus 로고
    • MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis
    • Najafi-Shoushtari SH, Kristo F, Li Y, Shioda T, Cohen DE, Gerszten RE, Naar AM. 2010. MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science 328:1566-1569. http:// dx.doi.org/10.1126/science.1189123.
    • (2010) Science , vol.328 , pp. 1566-1569
    • Najafi-Shoushtari, S.H.1    Kristo, F.2    Li, Y.3    Shioda, T.4    Cohen, D.E.5    Gerszten, R.E.6    Naar, A.M.7
  • 18
    • 84880288761 scopus 로고    scopus 로고
    • MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion
    • Soh J, Iqbal J, Queiroz J, Fernandez-Hernando C, Hussain MM. 2013. MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion. Nat Med 19:892-900. http://dx.doi.org/10.1038/nm.3200.
    • (2013) Nat Med , vol.19 , pp. 892-900
    • Soh, J.1    Iqbal, J.2    Queiroz, J.3    Fernandez-Hernando, C.4    Hussain, M.M.5
  • 21
    • 84885155219 scopus 로고    scopus 로고
    • MicroRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection
    • Spaniel C, Honda M, Selitsky SR, Yamane D, Shimakami T, Kaneko S, Lanford RE, Lemon SM. 2013. MicroRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection. PLoS One 8:e76867. http:// dx.doi.org/10.1371/journal.pone.0076867.
    • (2013) PLoS One , vol.8
    • Spaniel, C.1    Honda, M.2    Selitsky, S.R.3    Yamane, D.4    Shimakami, T.5    Kaneko, S.6    Lanford, R.E.7    Lemon, S.M.8
  • 22
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: A revolutionary tool for transcriptomics
    • Wang Z, Gerstein M, SnyderM. 2009. RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet 10:57-63. http://dx.doi.org/10.1038/ nrg2484.
    • (2009) Nat Rev Genet , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 25
    • 76649100139 scopus 로고    scopus 로고
    • Liver X receptor in cholesterol metabolism
    • Zhao C, Dahlman-Wright K. 2010. Liver X receptor in cholesterol metabolism. J Endocrinol 204:233-240. http://dx.doi.org/10.1677/JOE-09-0271.
    • (2010) J Endocrinol , vol.204 , pp. 233-240
    • Zhao, C.1    Dahlman-Wright, K.2
  • 26
    • 0036556688 scopus 로고    scopus 로고
    • LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis
    • Edwards PA, Kennedy MA, Mak PA. 2002. LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis. Vasc Pharmacol 38:249-256. http://dx.doi.org/10.1016/S1537-1891(02)00175-1.
    • (2002) Vasc Pharmacol , vol.38 , pp. 249-256
    • Edwards, P.A.1    Kennedy, M.A.2    Mak, P.A.3
  • 28
    • 84861539479 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner
    • Tanos R, Patel RD, Murray IA, Smith PB, Patterson AD, Perdew GH. 2012. Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner. Hepatology 55:1994-2004. http://dx.doi.org/10.1002/hep.25571.
    • (2012) Hepatology , vol.55 , pp. 1994-2004
    • Tanos, R.1    Patel, R.D.2    Murray, I.A.3    Smith, P.B.4    Patterson, A.D.5    Perdew, G.H.6
  • 29
    • 84883651731 scopus 로고    scopus 로고
    • Beta cell 5=-shifted isomiRs are candidate regulatory hubs in type 2 diabetes
    • Baran-Gale J, Fannin EE, Kurtz CL, Sethupathy P. 2013. Beta cell 5=-shifted isomiRs are candidate regulatory hubs in type 2 diabetes. PLoS One 8:e73240. http://dx.doi.org/10.1371/journal.pone.0073240.
    • (2013) PLoS One , vol.8
    • Baran-Gale, J.1    Fannin, E.E.2    Kurtz, C.L.3    Sethupathy, P.4
  • 30
    • 84876858736 scopus 로고    scopus 로고
    • HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1
    • Chen Y, Chen J, Wang H, Shi J, Wu K, Liu S, Liu Y, Wu J. 2013. HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1. PLoS Pathog 9:e1003248. http://dx.doi.org/ 10.1371/journal.ppat.1003248.
    • (2013) PLoS Pathog , vol.9
    • Chen, Y.1    Chen, J.2    Wang, H.3    Shi, J.4    Wu, K.5    Liu, S.6    Liu, Y.7    Wu, J.8
  • 33
    • 77958152970 scopus 로고    scopus 로고
    • Suppression of hepatitis B virus replication by microRNA-199a-3p and microRNA-210
    • Zhang GL, Li YX, Zheng SQ, Liu M, Li X, Tang H. 2010. Suppression of hepatitis B virus replication by microRNA-199a-3p and microRNA-210. Antiviral Res 88:169-1 7 5. http://dx.doi. org/1 0. 1 0 1 6 / j.antiviral.2010.08.008.
    • (2010) Antiviral Res , vol.88 , pp. 169-175
    • Zhang, G.L.1    Li, Y.X.2    Zheng, S.Q.3    Liu, M.4    Li, X.5    Tang, H.6
  • 37
    • 84898071462 scopus 로고    scopus 로고
    • Functional analysis of miR-101-3p and Rap1b involved in hepatitis B virus-related hepatocellular carcinoma pathogenesis
    • Sheng Y, Ding S, Chen K, Chen J, Wang S, Zou C, Zhang J, Cao Y, Huang A, Tang H. 2014. Functional analysis of miR-101-3p and Rap1b involved in hepatitis B virus-related hepatocellular carcinoma pathogenesis. Biochem Cell Biol 92:152-162. http://dx.doi.org/10.1139/bcb-2013-0128.
    • (2014) Biochem Cell Biol , vol.92 , pp. 152-162
    • Sheng, Y.1    Ding, S.2    Chen, K.3    Chen, J.4    Wang, S.5    Zou, C.6    Zhang, J.7    Cao, Y.8    Huang, A.9    Tang, H.10
  • 38
    • 84893081987 scopus 로고    scopus 로고
    • Autophagy suppresses tumorigenesis of hepatitis B virusassociated hepatocellular carcinoma through degradation of microRNA-224
    • Lan SH, Wu SY, Zuchini R, Lin XZ, Su IJ, Tsai TF, Lin YJ, Wu CT, Liu HS. 2014. Autophagy suppresses tumorigenesis of hepatitis B virusassociated hepatocellular carcinoma through degradation of microRNA-224. Hepatology 59:505-517. http://dx.doi.org/10.1002/hep.26659.
    • (2014) Hepatology , vol.59 , pp. 505-517
    • Lan, S.H.1    Wu, S.Y.2    Zuchini, R.3    Lin, X.Z.4    Su, I.J.5    Tsai, T.F.6    Lin, Y.J.7    Wu, C.T.8    Liu, H.S.9
  • 43
    • 34249819336 scopus 로고    scopus 로고
    • MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
    • Tsang J, Zhu J, van Oudenaarden A. 2007. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell 26:753-767. http://dx.doi.org/10.1016/j.molcel.2007.05.018.
    • (2007) Mol Cell , vol.26 , pp. 753-767
    • Tsang, J.1    Zhu, J.2    van Oudenaarden, A.3
  • 44
    • 80054764011 scopus 로고    scopus 로고
    • PPARalpha is regulated by miR-21 and miR-27b in human liver
    • Kida K, Nakajima M, Mohri T, Oda Y, Takagi S, Fukami T, Yokoi T. 2011. PPARalpha is regulated by miR-21 and miR-27b in human liver. Pharm Res 28:2467-2476. http://dx.doi.org/10.1007/s11095-011-0473-y.
    • (2011) Pharm Res , vol.28 , pp. 2467-2476
    • Kida, K.1    Nakajima, M.2    Mohri, T.3    Oda, Y.4    Takagi, S.5    Fukami, T.6    Yokoi, T.7
  • 45
    • 59849084351 scopus 로고    scopus 로고
    • Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation
    • Ji J, Zhang J, Huang G, Qian J, Wang X, Mei S. 2009. Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett 583:759-766. http:// dx.doi.org/10.1016/j.febslet.2009.01.034.
    • (2009) FEBS Lett , vol.583 , pp. 759-766
    • Ji, J.1    Zhang, J.2    Huang, G.3    Qian, J.4    Wang, X.5    Mei, S.6
  • 47
    • 79958716078 scopus 로고    scopus 로고
    • Human SREBP1c expression in liver is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha)
    • Fernandez-Alvarez A, Alvarez MS, Gonzalez R, Cucarella C, Muntane J, CasadoM. 2011. Human SREBP1c expression in liver is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha). J Biol Chem 286:21466-21477. http://dx.doi.org/10.1074/jbc.M110.209973.
    • (2011) J Biol Chem , vol.286 , pp. 21466-21477
    • Fernandez-Alvarez, A.1    Alvarez, M.S.2    Gonzalez, R.3    Cucarella, C.4    Muntane, J.5    Casado, M.6
  • 48
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi SW, Zang JB, Mele A, Darnell RB. 2009. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460:479-486. http://dx.doi.org/10.1038/nature08170.
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 49
    • 84873310018 scopus 로고    scopus 로고
    • Emerging role of microRNAs in the regulation of lipid metabolism
    • Fernández-Hernando C. 2013. Emerging role of microRNAs in the regulation of lipid metabolism. Hepatology 57:432-434. http://dx.doi.org/ 10.1002/hep.25960.
    • (2013) Hepatology , vol.57 , pp. 432-434
    • Fernández-Hernando, C.1
  • 51
    • 84921718665 scopus 로고    scopus 로고
    • miR-21 regulates triglyceride and cholesterol metabolism in nonalcoholic fatty liver disease by targeting HMGCR
    • Sun C, Huang F, Liu X, Xiao X, Yang M, Hu G, Liu H, Liao L. 2015. miR-21 regulates triglyceride and cholesterol metabolism in nonalcoholic fatty liver disease by targeting HMGCR. Int J Mol Med 35: 847-853. http://dx.doi.org/10.3892/ijmm.2015.2076.
    • (2015) Int J Mol Med , vol.35 , pp. 847-853
    • Sun, C.1    Huang, F.2    Liu, X.3    Xiao, X.4    Yang, M.5    Hu, G.6    Liu, H.7    Liao, L.8
  • 52
    • 0037324340 scopus 로고    scopus 로고
    • Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
    • Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P. 2003. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 9:213-219. http://dx.doi.org/10.1038/nm820.
    • (2003) Nat Med , vol.9 , pp. 213-219
    • Joseph, S.B.1    Castrillo, A.2    Laffitte, B.A.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 53
    • 63049122784 scopus 로고    scopus 로고
    • Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and antiinflammatory signaling pathways
    • Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK. 2009. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and antiinflammatory signaling pathways. Genes Dev 23:681-693. http:// dx.doi.org/10.1101/gad.1773109.
    • (2009) Genes Dev , vol.23 , pp. 681-693
    • Ghisletti, S.1    Huang, W.2    Jepsen, K.3    Benner, C.4    Hardiman, G.5    Rosenfeld, M.G.6    Glass, C.K.7
  • 54
    • 0038193542 scopus 로고    scopus 로고
    • Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages
    • Castrillo A, Joseph SB, Marathe C, Mangelsdorf DJ, Tontonoz P. 2003. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. J Biol Chem 278:10443-10449. http:// dx.doi.org/10.1074/jbc.M213071200.
    • (2003) J Biol Chem , vol.278 , pp. 10443-10449
    • Castrillo, A.1    Joseph, S.B.2    Marathe, C.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 56
    • 84901620722 scopus 로고    scopus 로고
    • Is genotype 3 of the hepatitis C virus the new villain?
    • Goossens N, Negro F. 2014. Is genotype 3 of the hepatitis C virus the new villain? Hepatology 59:2403-2412. http://dx.doi.org/10.1002/hep.26905.
    • (2014) Hepatology , vol.59 , pp. 2403-2412
    • Goossens, N.1    Negro, F.2
  • 57
  • 58
    • 84938633652 scopus 로고    scopus 로고
    • Inhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liver
    • Kurtz CL, Fannin EE, Toth CL, Pearson DS, Vickers KC, Sethupathy P. 2015. Inhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liver. Sci Rep 5:12911. http://dx.doi.org/10.1038/srep12911.
    • (2015) Sci Rep , vol.5
    • Kurtz, C.L.1    Fannin, E.E.2    Toth, C.L.3    Pearson, D.S.4    Vickers, K.C.5    Sethupathy, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.