Inhibition of Kallikrein-Related Peptidases 7 and 5 by Grafting Serpin Reactive-Center Loop Sequences onto Sunflower Trypsin Inhibitor-1 (SFTI-1)

ChemBioChem

Volumn 17, Issue 8, 2016, Pages 719-726

  Jendrny, Cathleen ^a   Beck Sickinger, Annette G ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

enzymes; inhibitors; peptides; reactive center loops; serpins; sunflower trypsin inhibitor 1

Indexed keywords

BOWMAN BIRK INHIBITOR; CHYMOTRYPSIN INHIBITOR; KALLIKREIN RELATED PEPTIDASE 5; KALLIKREIN RELATED PEPTIDASE 7; PLASMINOGEN ACTIVATOR INHIBITOR 3; SERINE PROTEINASE; SUNFLOWER TRYPSIN INHIBITOR 1; UNCLASSIFIED DRUG; CYCLOPEPTIDE; KALLIKREIN; KLK5 PROTEIN, HUMAN; KLK7 PROTEIN, HUMAN; PROTEIN BINDING; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR; SFTI-1 PEPTIDE, SUNFLOWER;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME KINETICS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEINASE INHIBITION; REACTIVE CENTER LOOP; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; SYNTHESIS;

HUMANS; KALLIKREINS; PEPTIDES, CYCLIC; PROTEIN BINDING; RECOMBINANT PROTEINS; SERINE PROTEINASE INHIBITORS; SERPINS;

EID: 84952674008     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201500539     Document Type: Article

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