Brain aging in African-Americans: The atherosclerosis risk in communities (ARIC) experience

Current Alzheimer Research

Volumn 12, Issue 7, 2015, Pages 607-613

  Gottesman, Rebecca F ^a   Fornage, Myriam ^b   Knopman, David S ^c   Mosley, Thomas H ^d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Brain MRI; Cognition; Dementia; Epidemiology; Racial disparities

Indexed keywords

APOLIPOPROTEIN E4; DNA; VITAMIN D;

AFRICAN AMERICAN; BLACK PERSON; BLOOD PRESSURE; BRAIN ATROPHY; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN SIZE; CAUCASIAN; CEREBROVASCULAR ACCIDENT; COGNITIVE DEFECT; CONFERENCE PAPER; DEMENTIA; DIABETES MELLITUS; GENETIC ASSOCIATION; GENETIC DIFFERENCE; HEALTH CARE ACCESS; HUMAN; HYPERTENSION; INCOME; LACUNAR STROKE; LEUKOARAIOSIS; MICROANGIOPATHY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PRIORITY JOURNAL; RACE DIFFERENCE; RISK FACTOR; SICKLE CELL TRAIT; SMOKING; SOCIAL STATUS; TRANSIENT ISCHEMIC ATTACK; WHITE MATTER LESION; AGED; AGING; ATHEROSCLEROSIS; BRAIN; BRAIN DISEASE; EPIDEMIOLOGY; ETHNOLOGY; FEMALE; FOLLOW UP; GENETICS; LONGITUDINAL STUDY; MALE; MIDDLE AGED; PATHOLOGY; PSYCHOLOGY; RISK; UNITED STATES; VERY ELDERLY;

AFRICAN AMERICANS; AGED; AGED, 80 AND OVER; AGING; ATHEROSCLEROSIS; BRAIN; BRAIN DISEASES; FEMALE; FOLLOW-UP STUDIES; HUMANS; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RISK; UNITED STATES;

EID: 84952672057     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/1567205012666150701102445     Document Type: Conference Paper

References (47)

1. [1] Pickle LW, Mungiole M, Gillum RF. Geographic variation in stroke mortality in blacks and whites in the United States. Stroke 28(8): 1639-1647 (1997).
2. [2] Roccella EJ, Lenfant C. Regional and racial differences among stroke victims in the United States. Clin Cardiol 12(4): IV18-22(1989).
3. [3] Husaini BA, Sherkat DE, Moonis M, Levine R, Holzer C, Cain VA. Racial differences in the diagnosis of dementia and in its effects on the use and costs of health care services. Psychiatr Serv 65(1): 92-96 (2003).
4. [4] Gutierrez J, Williams OA. A decade of racial and ethnic stroke disparities in the United States. Neurology 82(12): 1080-1082 (2014).
5. [5] Center for Disease Control and Prevention (CDC). National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States. 2011; http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf.
6. [6] Howard G, Prineas R, Moy C, Cushman M, Kellum M, Temple E, et al. Racial and geographic differences in awareness, treatment, and control of hypertension: the reasons for geographic and racial differences in stroke study. Stroke 37(5): 1171-1178 (2006).
7. [7] The ARIC Investigators. The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. Am J Epidemiol 129: 687-702 (1989).
8. [8] Schneider AL, Gottesman RF, Mosley, TH, Alonso A, Knopman DS, Coresh J, et al. Cognition and incident dementia hospitalization: results from the atherosclerosis risk in communities study. Neuroepidemiology 40(2):117-12 (2013).
9. [9] Toole JF, Chambless LE, Heiss G, Tyroler HA, Paton CC. Prevalence of stroke and transient ischemic attacks in the Atherosclerosis Risk in Communities (ARIC) Study. Ann Epidemiol 3: 500-503 (1993).
10. [10] Koton S, Schneider ALC, Rosamond WD, Shahar E, Sang Y, Gottesman RF, et al. Stroke incidence and mortality trends in US communities, 1987 to 2011. JAMA 312(3): 259-268 (2014).
11. [11] Ohira T, Shahar E, Chambless LE, Rosamond WD, Mosley, TH, Folsom AR. Risk factors for ischemic stroke subtypes. The Atherosclerosis Risk in Communities Study. Stroke 37(10): 2493-2498 (2006).
12. [12] Jones SA, Gottesman RF, Shahar E, Wruck L, Rosamond WD. Validity of hospital discharge codes for stroke: the Atherosclerosis Risk in Communities Study. Stroke 45(11): 3219-3225 (2014).
13. [13] Chambless LE, Shahar E, Sharrett AR, Heiss G, Wijnberg L, Paton CC, et al. Association of transient ischemic attack/ stroke symptoms assessed by standardized questionnaire and algorithm with cerebrovascular risk factors and carotid artery wall thickness. Am J Epidemiol 144: 857-866 (1996).
14. [14] Yatsuya H, Folsom AR, Yamagishi K, North KE, Brancati FL, Stevens J. Race- and Sex-specific associations of obesity measures with ischemic stroke incidence in the Atherosclerosis Risk in Communities (ARIC) Study. Stroke 41: 417-425 (2010).
15. [15] Huxley RR, Bell EJ, Lutsey PL, Bushnell C, Shahar E, Rosamond W, et al. A comparative analysis of risk factors for stroke in blacks and whites: the Atherosclerosis Risk in Communities study. Ethn Health 19(6): 601-616 (2014).
16. [16] Caughey MC, Loehr LR, Key NS, Derebail VK, Gottesman RF, Kshirsagar AV, et al. Sickle cell trait and incident ischemic stroke in the Atherosclerosis Risk in Communities study. Stroke 45(10): 2863-2867 (2014).
17. [17] Sacco RL, Kasner SE, Broderick JP, Caplan LR, Connors JJ, Culebras A, et al. An updated definition of stroke for the 21st century: A statement for healthcare professionals from the American Heart Association/ American Stroke Association. Stroke 44: 2064-2089 (2013).
18. [18] Bryan RN, Cai J, Burke G, Hutchinson RG, Liao D, Toole JF, et al. Prevalence and anatomic characteristics of infarct-like lesions on MR images of middle-aged adults: the Atherosclerosis Risk in Communities Study. Am J Neuroradiol 20(7):1273-1280 (1999).
19. [19] Liao D, Cooper L, Cai J, Toole JF, Bryan NR, Hutchinson RG, et al. Presence and severity of cerebral white matter lesions and hypertension, its treatment, and its control. The ARIC Study. Atherosclerosis Risk in Communities Study. Stroke 27(12): 2262-2270 (1996).
20. [20] Knopman DS, Mosley TH, Catellier DJ, Sharrett AR. Cardiovascular risk factors and cerebral atrophy in a middle-aged cohort. Neurology 65: 876-881 (2005).
21. [21] Knopman DS, Penman AD, Catellier DJ, Coker LH, Shibata DK, Sharrett AR, et al. Vascular risk factors and longitudinal changes on brain MRI. Neurology 76(22):1879-1885 (2011).
22. [22] Liao D, Cooper L, Cai J, Toole J, Bryan N, Burke G, et al. The prevalence and severity of white matter lesions, their relationship with age, ethnicity, gender, and cardiovascular disease risk factors: the ARIC Study. Neuroepidemiology 16(3):149-162 (1997).
23. [23] Brickman AM, Schupf N, Manly JJ, Luchsinger JA, Andrews H, Tang MX, et al. Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern Manhattan. Arch Neurol 65(8):1053-1061 (2008).
24. [24] Power MC, Deal J, Sharrett AR, Jack CR Jr, Knopman D, Mosley TH, et al. Smoking and white matter hyperintensity progression: The ARIC-MRI Study. Neurology 84(8): 841-8 (2015).
25. [25] Gottesman RF, Coresh J, Catellier DJ, Sharrett AR, Rose KM, Coker LH, et al. Blood pressure and white matter disease progression in a biethnic cohort: Atherosclerosis Risk in Communities (ARIC) Study. Stroke 41: 3-8 (2010).
26. [26] Hanff TC, Sharrett AR, Mosley TH, Shibata D, Knopman DS, Klein R, et al. Retinal microvascular abnormalities predict progression of brain microvascular disease: an Atherosclerosis Risk in Communities Magnetic Resonance Imaging study. Stroke 45(4): 1012-1017 (2014).
27. [27] Gottesman RF, Rawlings AM, Sharrett AR, Albert M, Alonso A, Bandeen-Roche K, et al. Impact of differential attrition in the association of education with cognitive change over 20 years of follow-up: the ARIC-Neurocognitive Study. Am J Epidemiol 179(8): 956-966 (2014).
28. [28] Fitzpatrick AL, Kuller LH, Ives DG, Lopez OL, Jagust W, Breitner JC, et al. Incidence and prevalence of dementia in the Cardiovascular Health Study. J Am Geriatr Soc 52(2): 195-204 (2004).
29. [29] Tang MX, Cross P, Andrews H, Jacobs DM, Small S, Bell K, et al. Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan. Neurology 56(1): 49-56 (2001).
30. [30] Demirovic J, Prineas R, Loewenstein D, Bean J, Duara R, Sevush S, et al. Prevalence of dementia in three ethnic groups: the South Florida program on aging and health. Ann Epidemiol 13(6): 472-478 (2003).
31. [31] Shadlen MF, Siscovick D, Fitzpatrick AL, Dulberg C, Kuller LH, Jackson S. Education, cognitive test scores, and black-white differences in dementia risk. J Am Geriatr Soc 54(6): 898-905 (2006).
32. [32] Gottesman RF, Schneider ALC, Albert M, Alonso A, Bandeen-Roche K, Coker L, et al. Midlife hypertension and 20-year cognitive change. The Atherosclerosis Risk in Communities Neurocognitive Study. JAMA Neurol 71(10):1218-1227 (2014).
33. [33] Rawlings AM, Sharrett AR, Schneider ALC, Coresh J, Albert M, Couper D, et al. Diabetes in midlife and cognitive change over 20 years: the Atherosclerosis Risk in Communities Neurocognitive Study. Ann Intern Med 161(11): 785-793 (2014).
34. [34] Blair CK, Folsom AR, Knopman DS, Bray MS, Mosley TH, Boerwinkle E, et al. APOE genotype and cognitive decline in a middle-aged cohort. Neurology 64(2): 268-276 (2005).
35. [35] Schneider ALC, Sharrett AR, Gottesman RF, Coresh J, Coker L, Wruck L, et al. Normative data for eight common neuropsychological tests for blacks and whites from the Atherosclerosis Risk in Communities (ARIC) Study. Alzheimer's Dis Assoc Disord 29(1): 32-44 (2015).
36. [36] Alonso A, Mosley Jr. TH, Gottesman RF, Catellier DJ, Sharrett AR, Coresh J. Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study. J Neurol Neurosurg Psychiatry 80(11): 1194-1201 (2009).
37. [37] Schneider AL, Lutsey PL, Alonso A, Gottesman RF, Sharrett AR, Carson KA, et al. Vitamin D and cognitive function and dementia risk in a biracial cohort: the ARIC Brain MRI Study. Eur J Neurol 21(9):1211-1218 (2014).
38. [38] Ikram MA, Seshadri S, Bis JC, Fornage M, DeStefano AL, Aulchenko YS, et al. Genomewide association studies of stroke. N Engl J Med 360(17):1718-1728 (2009).
39. [39] Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, et al. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol 69(6): 928-939 (2011).
40. [40] Deary I, Davies G, Armstrong N, Bressler J, Chouraki V, Giddaluru S, et al. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium. Mol Psychiatry 20(2): 183-92 (2015).
41. [41] Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet 45(12): 1452-1458 (2013).
42. [42] Franceschini N, Fox ER, Zhang Z, Edward TL, Nalls MA, Sung YJ, et al. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet 93(3): 545-554 (2013).
43. [43] Carlson CS, Matise TC, North KE, Haiman CA, Fesinmeyer MD, Buyske S, et al. Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study. PLoS Biol 11(9): e1001661 (2013).
44. [44] Debette S, Bis JC, Fornage M, et al. Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE consortium. Stroke 41(2): 210-217 (2010).
45. [45] Verhaaren BFJ, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, et al. Multi-ethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circ Cardiovasc Genet 8(2): 398-409 (2015).
46. [46] Hutchinson RG, Watson RL, Davis CE, Barnes R, Brown S, Romm F, et al. Racial differences in risk factors for atherosclerosis. The ARIC Study. Atherosclerosis Risk in Communities. Angiology 48(4): 279-290 (1997).
47. [47] Arvanitakis Z, Bennett DA, Wilson RS, Barnes LL. Diabetes and cognitive systems in older black and white persons. Alzheimer Dis Assoc Disord 24(1): 37-42 (2010).