Telomerase reverse transcriptase promoter methylation is related to a risk of recurrence in hepatocellular carcinoma

Hepatology

Volumn 63, Issue 1, 2016, Pages 341-

  Ko, Eunkyong ^a   Jung, Eun Sun ^b   Jung, Guhung ^a  

^a Seoul National University   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE; TELOMERASE; TUMOR MARKER;

CANCER RECURRENCE; GENE EXPRESSION; HUMAN; LETTER; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; RECURRENCE FREE SURVIVAL; SOMATIC MUTATION; CARCINOMA, HEPATOCELLULAR; COMPLICATION; FEMALE; GENETICS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; PRECANCER;

BIOMARKERS, TUMOR; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; PRECANCEROUS CONDITIONS; TELOMERASE;

EID: 84952639709     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27833     Document Type: Letter

References (3)

1. Nault JC, Calderaro J, Di Tommaso L, Balabaud C, Zafrani ES, Bioulac-Sage P, et al. Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis. Hepatology 2014;60:1983-1992.
2. Dessain SK, Yu H, Reddel RR, Beijersbergen RL, Weinberg RA. Methylation of the human telomerase gene CpG island. Cancer Res 2000;60:537-541.
3. Castelo-Branco P, Choufani S, Mack S, Gallagher D, Zhang C, Lipman T, et al. Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study. Lancet Oncol 2013;14:534-542.