-
2
-
-
79955631558
-
Genetics of hepatobiliary carcinogenesis
-
Nault JC, Zucman-Rossi J. Genetics of hepatobiliary carcinogenesis. Semin Liver Dis 2011;31:173-187.
-
(2011)
Semin Liver Dis
, vol.31
, pp. 173-187
-
-
Nault, J.C.1
Zucman-Rossi, J.2
-
3
-
-
61949171989
-
Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia
-
International Working Party. Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia. Hepatology 2009;49:658-664.
-
(2009)
Hepatology
, vol.49
, pp. 658-664
-
-
-
4
-
-
61749103943
-
The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma
-
Di Tommaso L, Destro A, Seok JY, Balladore E, Terracciano L, Sangiovanni A, et al. The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma. J Hepatol 2009;50:746-754.
-
(2009)
J Hepatol
, vol.50
, pp. 746-754
-
-
Di Tommaso, L.1
Destro, A.2
Seok, J.Y.3
Balladore, E.4
Terracciano, L.5
Sangiovanni, A.6
-
5
-
-
33947396135
-
Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis
-
Di Tommaso L, Franchi G, Park YN, Fiamengo B, Destro A, Morenghi E, et al. Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis. Hepatology 2007;45:725-734.
-
(2007)
Hepatology
, vol.45
, pp. 725-734
-
-
Di Tommaso, L.1
Franchi, G.2
Park, Y.N.3
Fiamengo, B.4
Destro, A.5
Morenghi, E.6
-
6
-
-
34247549347
-
Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma
-
Wurmbach E, Chen YB, Khitrov G, Zhang W, Roayaie S, Schwartz M, et al. Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma. Hepatology 2007;45:938-947.
-
(2007)
Hepatology
, vol.45
, pp. 938-947
-
-
Wurmbach, E.1
Chen, Y.B.2
Khitrov, G.3
Zhang, W.4
Roayaie, S.5
Schwartz, M.6
-
7
-
-
33845790499
-
A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis
-
Llovet JM, Chen Y, Wurmbach E, Roayaie S, Fiel MI, Schwartz M, et al. A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis. Gastroenterology 2006;131:1758-1767.
-
(2006)
Gastroenterology
, vol.131
, pp. 1758-1767
-
-
Llovet, J.M.1
Chen, Y.2
Wurmbach, E.3
Roayaie, S.4
Fiel, M.I.5
Schwartz, M.6
-
8
-
-
84866109451
-
Prospective validation of an immunohistochemical panel (glypican 3, heat shock protein 70 and glutamine synthetase) in liver biopsies for diagnosis of very early hepatocellular carcinoma
-
Tremosini S, Forner A, Boix L, Vilana R, Bianchi L, Reig M, et al. Prospective validation of an immunohistochemical panel (glypican 3, heat shock protein 70 and glutamine synthetase) in liver biopsies for diagnosis of very early hepatocellular carcinoma. Gut 2012;61:1481-1487.
-
(2012)
Gut
, vol.61
, pp. 1481-1487
-
-
Tremosini, S.1
Forner, A.2
Boix, L.3
Vilana, R.4
Bianchi, L.5
Reig, M.6
-
9
-
-
0042093775
-
Impact of large regenerative, low grade and high grade dysplastic nodules in hepatocellular carcinoma development
-
Borzio M, Fargion S, Borzio F, Fracanzani AL, Croce AM, Stroffolini T, et al. Impact of large regenerative, low grade and high grade dysplastic nodules in hepatocellular carcinoma development. J Hepatol 2003;39:208-214.
-
(2003)
J Hepatol
, vol.39
, pp. 208-214
-
-
Borzio, M.1
Fargion, S.2
Borzio, F.3
Fracanzani, A.L.4
Croce, A.M.5
Stroffolini, T.6
-
10
-
-
0031732647
-
Histological features predicting malignant transformation of nonmalignant hepatocellular nodules: a prospective study
-
Terasaki S, Kaneko S, Kobayashi K, Nonomura A, Nakanuma Y. Histological features predicting malignant transformation of nonmalignant hepatocellular nodules: a prospective study. Gastroenterology 1998;115:1216-1222.
-
(1998)
Gastroenterology
, vol.115
, pp. 1216-1222
-
-
Terasaki, S.1
Kaneko, S.2
Kobayashi, K.3
Nonomura, A.4
Nakanuma, Y.5
-
11
-
-
84879787163
-
Advanced precancerous lesions in the liver
-
Di Tommaso L, Sangiovanni A, Borzio M, Park YN, Farinati F, Roncalli M. Advanced precancerous lesions in the liver. Best Pract Res Clin Gastroenterol 2013;27:269-284.
-
(2013)
Best Pract Res Clin Gastroenterol
, vol.27
, pp. 269-284
-
-
Di Tommaso, L.1
Sangiovanni, A.2
Borzio, M.3
Park, Y.N.4
Farinati, F.5
Roncalli, M.6
-
12
-
-
82455210770
-
Radiofrequency ablation of high-grade dysplastic nodules
-
Cho YK, Wook Chung J, Kim Y, Je Cho H, Hyun Yang S. Radiofrequency ablation of high-grade dysplastic nodules. Hepatology 2011;54:2005-2011.
-
(2011)
Hepatology
, vol.54
, pp. 2005-2011
-
-
Cho, Y.K.1
Wook Chung, J.2
Kim, Y.3
Je Cho, H.4
Hyun Yang, S.5
-
13
-
-
84858658381
-
EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma
-
European Organisation For Research And Treatment Of Cancer
-
European Association For The Study Of The Liver; European Organisation For Research And Treatment Of Cancer. EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol 2012;56:908-943.
-
(2012)
J Hepatol
, vol.56
, pp. 908-943
-
-
-
14
-
-
79952231921
-
Management of hepatocellular carcinoma: an update
-
Bruix J, Sherman M. Management of hepatocellular carcinoma: an update. Hepatology 2011;53:1020-1022.
-
(2011)
Hepatology
, vol.53
, pp. 1020-1022
-
-
Bruix, J.1
Sherman, M.2
-
16
-
-
84881436148
-
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions
-
Nault JC, Mallet M, Pilati C, Calderaro J, Bioulac Sage P, Laurent C, et al. High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions. Nat Commun 2013;4:2218.
-
(2013)
Nat Commun
, vol.4
, pp. 2218
-
-
Nault, J.C.1
Mallet, M.2
Pilati, C.3
Calderaro, J.4
Bioulac Sage, P.5
Laurent, C.6
-
17
-
-
84861625981
-
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
-
Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad IB, et al. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 2012;44:694-698.
-
(2012)
Nat Genet
, vol.44
, pp. 694-698
-
-
Guichard, C.1
Amaddeo, G.2
Imbeaud, S.3
Ladeiro, Y.4
Pelletier, L.5
Maad, I.B.6
-
18
-
-
84862976633
-
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
-
Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, Nguyen HH, et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet 2012;44:760-764.
-
(2012)
Nat Genet
, vol.44
, pp. 760-764
-
-
Fujimoto, A.1
Totoki, Y.2
Abe, T.3
Boroevich, K.A.4
Hosoda, F.5
Nguyen, H.H.6
-
19
-
-
84887022334
-
Identification of driver genes in hepatocellular carcinoma by exome sequencing
-
Cleary SP, Jeck WR, Zhao X, Kuichen, Selitsky SR, Savich GL, et al. Identification of driver genes in hepatocellular carcinoma by exome sequencing. Hepatology 2013;58:1693-1702.
-
(2013)
Hepatology
, vol.58
, pp. 1693-1702
-
-
Cleary, S.P.1
Jeck, W.R.2
Zhao, X.3
Kuichen4
Selitsky, S.R.5
Savich, G.L.6
-
20
-
-
33846463379
-
Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
-
Boyault S, Rickman DS, de Reynies A, Balabaud C, Rebouissou S, Jeannot E, et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology 2007;45:42-52.
-
(2007)
Hepatology
, vol.45
, pp. 42-52
-
-
Boyault, S.1
Rickman, D.S.2
de Reynies, A.3
Balabaud, C.4
Rebouissou, S.5
Jeannot, E.6
-
21
-
-
0029155354
-
Terminology of nodular hepatocellular lesions
-
International Working Party. Terminology of nodular hepatocellular lesions. Hepatology 1995;22:983-993.
-
(1995)
Hepatology
, vol.22
, pp. 983-993
-
-
-
22
-
-
84894271589
-
High Incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression
-
Goutagny S, Nault JC, Mallet M, Henin D, Rossi JZ, Kalamarides M. High Incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression. Brain Pathol 2014;24:184-189.
-
(2014)
Brain Pathol
, vol.24
, pp. 184-189
-
-
Goutagny, S.1
Nault, J.C.2
Mallet, M.3
Henin, D.4
Rossi, J.Z.5
Kalamarides, M.6
-
23
-
-
84904245633
-
Overexpression and promoter mutation of the TERT gene in malignant pleural mesothelioma
-
Tallet A, Nault JC, Renier A, Hysi I, Galateau-Salle F, Cazes A, et al. Overexpression and promoter mutation of the TERT gene in malignant pleural mesothelioma. Oncogene 2014;33:3748-3752.
-
(2014)
Oncogene
, vol.33
, pp. 3748-3752
-
-
Tallet, A.1
Nault, J.C.2
Renier, A.3
Hysi, I.4
Galateau-Salle, F.5
Cazes, A.6
-
24
-
-
84884524540
-
Frequency of TERT promoter mutations in human cancers
-
Vinagre J, Almeida A, Populo H, Batista R, Lyra J, Pinto V, et al. Frequency of TERT promoter mutations in human cancers. Nat Commun 2013;4:2185.
-
(2013)
Nat Commun
, vol.4
, pp. 2185
-
-
Vinagre, J.1
Almeida, A.2
Populo, H.3
Batista, R.4
Lyra, J.5
Pinto, V.6
-
25
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
26
-
-
84898989382
-
Hepatocellular carcinoma: reasons for phase III failure and novel perspectives on trial design
-
Llovet JM, Hernandez-Gea V. Hepatocellular carcinoma: reasons for phase III failure and novel perspectives on trial design. Clin Cancer Res 2014;20:2072-2079.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2072-2079
-
-
Llovet, J.M.1
Hernandez-Gea, V.2
-
27
-
-
33645223878
-
Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC
-
Zucman-Rossi J, Jeannot E, Nhieu JT, Scoazec JY, Guettier C, Rebouissou S, et al. Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC. Hepatology 2006;43:515-524.
-
(2006)
Hepatology
, vol.43
, pp. 515-524
-
-
Zucman-Rossi, J.1
Jeannot, E.2
Nhieu, J.T.3
Scoazec, J.Y.4
Guettier, C.5
Rebouissou, S.6
-
28
-
-
84876494014
-
Hepatocellular benign tumors-from molecular classification to personalized clinical care
-
Nault JC, Bioulac-Sage P, Zucman-Rossi J. Hepatocellular benign tumors-from molecular classification to personalized clinical care. Gastroenterology 2013;144:888-902.
-
(2013)
Gastroenterology
, vol.144
, pp. 888-902
-
-
Nault, J.C.1
Bioulac-Sage, P.2
Zucman-Rossi, J.3
-
29
-
-
84898445933
-
Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation
-
Pilati C, Letouze E, Nault JC, Imbeaud S, Boulai A, Calderaro J, et al. Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation. Cancer Cell 2014;25:428-441.
-
(2014)
Cancer Cell
, vol.25
, pp. 428-441
-
-
Pilati, C.1
Letouze, E.2
Nault, J.C.3
Imbeaud, S.4
Boulai, A.5
Calderaro, J.6
-
30
-
-
78651245794
-
Changing trends in malignant transformation of hepatocellular adenoma
-
Farges O, Ferreira N, Dokmak S, Belghiti J, Bedossa P, Paradis V. Changing trends in malignant transformation of hepatocellular adenoma. Gut 2011;60:85-89.
-
(2011)
Gut
, vol.60
, pp. 85-89
-
-
Farges, O.1
Ferreira, N.2
Dokmak, S.3
Belghiti, J.4
Bedossa, P.5
Paradis, V.6
-
31
-
-
36549031182
-
Nuclear beta-catenin staining and absence of steatosis are indicators of hepatocellular adenomas with an increased risk of malignancy
-
Van der Borght S, Libbrecht L, Katoonizadeh A, Aerts R, Nevens F, Verslype C, Roskams TA. Nuclear beta-catenin staining and absence of steatosis are indicators of hepatocellular adenomas with an increased risk of malignancy. Histopathology 2007;51:855-856.
-
(2007)
Histopathology
, vol.51
, pp. 855-856
-
-
Van der Borght, S.1
Libbrecht, L.2
Katoonizadeh, A.3
Aerts, R.4
Nevens, F.5
Verslype, C.6
Roskams, T.A.7
-
32
-
-
79953210046
-
Liver precancerous lesions and hepatocellular carcinoma: the histology report
-
Roncalli M, Terracciano L, Di Tommaso L, David E, Colombo M. Liver precancerous lesions and hepatocellular carcinoma: the histology report. Dig Liver Dis 2011;43(Suppl 4):S361-S372.
-
(2011)
Dig Liver Dis
, vol.43
, pp. S361-S372
-
-
Roncalli, M.1
Terracciano, L.2
Di Tommaso, L.3
David, E.4
Colombo, M.5
-
33
-
-
79955080781
-
Diagnostic accuracy of clathrin heavy chain staining in a marker panel for the diagnosis of small hepatocellular carcinoma
-
Di Tommaso L, Destro A, Fabbris V, Spagnuolo G, Laura Fracanzani A, Fargion S, et al. Diagnostic accuracy of clathrin heavy chain staining in a marker panel for the diagnosis of small hepatocellular carcinoma. Hepatology 2011;53:1549-1557.
-
(2011)
Hepatology
, vol.53
, pp. 1549-1557
-
-
Di Tommaso, L.1
Destro, A.2
Fabbris, V.3
Spagnuolo, G.4
Laura Fracanzani, A.5
Fargion, S.6
-
34
-
-
79958219307
-
EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies
-
Cai MY, Tong ZT, Zheng F, Liao YJ, Wang Y, Rao HL, et al. EZH2 protein: a promising immunomarker for the detection of hepatocellular carcinomas in liver needle biopsies. Gut 2011;60:967-976.
-
(2011)
Gut
, vol.60
, pp. 967-976
-
-
Cai, M.Y.1
Tong, Z.T.2
Zheng, F.3
Liao, Y.J.4
Wang, Y.5
Rao, H.L.6
|