Using NGF heparin-poloxamer thermosensitive hydrogels to enhance the nerve regeneration for spinal cord injury

Acta Biomaterialia

Volumn 29, Issue , 2016, Pages 71-80

  Zhao, Ying Zheng ^a,b,c   Jiang, Xi ^d   Xiao, Jian ^a   Lin, Qian ^a   Yu, Wen Ze ^a   Tian, Fu Rong ^a   Mao, Kai Li ^a   Yang, Wei ^a   Wong, Ho Lun ^e   Lu, Cui Tao ^a,b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^c HAINAN MEDICAL UNIVERSITY   (China)

^d Zhejiang University Mingzhou Hospital   (China)

^e TEMPLE UNIVERSITY SCHOOL OF PHARMACY   (United States)

Author keywords

Controlled release; Nerve growth factor (NGF); Nerve regeneration; Spinal cord injury; Thermosensitive hydrogel

Indexed keywords

BLOOD; CELL DEATH; CELL MEMBRANES; GELATION; HYDROGELS; NEURONS; PATIENT REHABILITATION; RATS; TISSUE;

CONTROLLED RELEASE; NERVE GROWTH FACTOR; NERVE REGENERATION; PHYSICO-CHEMICAL STABILITY; POLOXAMER; POLOXAMER HYDROGELS; SPINAL CORD INJURY; SPINAL-CORD; THERMO-SENSITIVE HYDROGEL;

POLYSACCHARIDES;

CD31 ANTIGEN; CEFAZOLIN; DRUG CARRIER; FLUORESCEIN ISOTHIOCYANATE; HEPARIN; NERVE GROWTH FACTOR; NEUROPROTECTIVE AGENT; POLOXAMER; DELAYED RELEASE FORMULATION; HYDROGEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CELL SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ENDOPLASMIC RETICULUM STRESS; GELATION; HEAT SENSITIVITY; HYDROGEL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROMORPHOLOGY; MOTOR PERFORMANCE; NERVE REGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; SPINAL CORD INJURY; SURVIVAL RATE; TEMPERATURE; ANIMAL; DELAYED RELEASE FORMULATION; DRUG EFFECTS; FEMALE; HEAT; MORTALITY; PATHOLOGY; PC12 CELL LINE; PHARMACOKINETICS; PHARMACOLOGY; SPINAL CORD INJURIES; SPRAGUE DAWLEY RAT;

ANIMALS; DELAYED-ACTION PREPARATIONS; FEMALE; HEPARIN; HOT TEMPERATURE; HYDROGELS; NERVE GROWTH FACTOR; NERVE REGENERATION; PC12 CELLS; POLOXAMER; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES;

EID: 84952637236     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2015.10.014     Document Type: Article

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