Hyperuricemia and risk of nonalcoholic fatty liver disease: A systematic review and meta-analysis

European Journal of Gastroenterology and Hepatology

Volumn 28, Issue 2, 2016, Pages 132-138

  Gong, Shulan ^a   Song, Jiqing ^b   Wang, Luan ^a   Zhang, Shuaiqing ^a   Wang, Yangang ^a  

^a QINGDAO UNIVERSITY   (China)

^b Department of Neurology   (China)

Author keywords

Hyperuricemia; Meta analysis; Nonalcoholic fatty liver disease

Indexed keywords

ARTICLE; CLINICAL ASSESSMENT; COHORT ANALYSIS; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; EMBASE; HUMAN; HYPERURICEMIA; MEDLINE; META ANALYSIS; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK FACTOR; SYSTEMATIC REVIEW; WANFANG DATABASE; WEB OF SCIENCE; ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD; FEMALE; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; ODDS RATIO; PREVALENCE; RISK ASSESSMENT; SEX DIFFERENCE; VERY ELDERLY;

BIOLOGICAL MARKER; URIC ACID;

ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; BIOMARKERS; FEMALE; HUMANS; HYPERURICEMIA; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; ODDS RATIO; PREVALENCE; RISK ASSESSMENT; RISK FACTORS; SEX FACTORS; URIC ACID;

EID: 84952631143     PISSN: 0954691X     EISSN: 14735687     Source Type: Journal    
DOI: 10.1097/MEG.0000000000000507     Document Type: Article

References (44)

1. Bambha K, Belt P, Abraham M, Wilson LA, Pabst M, Ferrell L, et al. Ethnicity and nonalcoholic fatty liver disease. Hepatology 2012; 55:769-780.
2. Machado MV, Cortez-Pinto H. Non-invasive diagnosis of non-Alcoholic fatty liver disease. A critical appraisal. J Hepatol 2013; 58:1007-1019.
3. Farrell GC, Wong VW, Chitturi S. NAFLD in Asia-As common and important as in the West. Nat Rev Gastroenterol Hepatol 2013; 10:307-318.
4. Anstee QM, Targher G, Day CP. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat Rev Gastroenterol Hepatol 2013; 10:330-344.
5. Bonora E, Targher G. Increased risk of cardiovascular disease and chronic kidney disease in NAFLD. Nat Rev Gastroenterol Hepatol 2012; 9:372-381.
6. Park SK, Seo MH, Shin HC, Ryoo JH. Clinical availability of nonalcoholic fatty liver disease as an early predictor of type 2 diabetes mellitus in Korean men: 5-year prospective cohort study. Hepatology 2013; 57:1378-1383.
7. White DL, Kanwal F, El-Serag HB. Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review. Clin Gastroenterol Hepatol 2012; 10:1342-1359 e1342.
8. Targher G, Byrne CD. Clinical review: nonalcoholic fatty liver disease: a novel cardiometabolic risk factor for type 2 diabetes and its complications. J Clin Endocrinol Metab 2013; 98:483-495.
9. Grayson PC, Kim SY, LaValley M, Choi HK. Hyperuricemia and incident hypertension: a systematic review and meta-Analysis. Arthritis Care Res (Hoboken) 2011; 63:102-110.
10. Kim SY, Guevara JP, Kim KM, Choi HK, Heitjan DF, Albert DA. Hyperuricemia and coronary heart disease: a systematic review and meta-Analysis. Arthritis Care Res (Hoboken) 2010; 62:170-180.
11. Kim SY, Guev ara JP, Kim KM, Choi HK, Heitjan DF, Albert DA. Hyperuricemia and risk of stroke: a systematic review and metaanalysis. Arthritis Rheum 2009; 61:885-892.
12. Kim HJ, Lee KE, Kim DJ, Kim SK, Ahn CW, Lim SK, et al. Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults. Arch Intern Med 2004; 164:2169-2175.
13. Cai W, Wu X, Zhang B, Miao L, Sun YP, Zou Y, et al. Serum uric acid levels and non-Alcoholic fatty liver disease in Uyghur and Han ethnic groups in northwestern China. Arq Bras Endocrinol Metabol 2013; 57:617-622.
14. Tung TH,Chang TH,Chiu WH,Lin TH,Shih HC,Chang MH,et al. Clinical correlation of nonalcoholic fatty liver disease in a Chinese taxi drivers population in Taiwan: experience at a teaching hospital BMC Res Notes 2011 4 315.
15. Lee K, Sung JA, Kim JS, Park TJ. The roles of obesity and gender on the relationship between metabolic risk factors and non-Alcoholic fatty liver disease in Koreans. Diabetes Metab Res Rev 2009; 25:150-155.
16. Chen CH, Huang MH, Yang JC, Nien CK, Yang CC, Yeh YH, et al. Prevalence and risk factors of nonalcoholic fatty liver disease in an adult population of Taiwan: metabolic significance of nonalcoholic fatty liver disease in nonobese adults. J Clin Gastroenterol 2006; 40:745-752.
17. Li Y, Xu C, Yu C, Xu L, Miao M. Association of serum uric acid level with non-Alcoholic fatty liver disease: a cross-sectional study. J Hepatol 2009; 50:1029-1034.
18. Ryu S , Chang Y, Kim SG, Cho J, Guallar E. Serum uric acid levels predict incident nonalcoholic fatty liver disease in healthy Korean men. Metabolism 2011; 60:860-866.
19. DerSimonian R, Laird N . Meta-Analysis in clinical trials. Control Clin Trials 1986; 7:177-188.
20. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-Analyses. BMJ 2003; 327:557-560.
21. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-Analysis detected by a simple, graphical test. BMJ 1997; 315:629-634.
22. Peters JL, Sut ton AJ, Jones DR, Abrams KR, Rushton L. Performance of the trim and fill method in the presence of publication bias and between-study heterogeneity. Stat Med 2007; 26:4544-4562.
23. Cai W, Song JM, Zha ng B, Sun YP, Yao H, Zhang YX. The prevalence of nonalcoholic fatty liver disease and relationship with serum uric acid level in Uyghur population. ScientificWorldJournal 2014; 2014:393628.
24. Huang X, Qiu Y, Wu Y, Lan Y. The prevalence and risk factors of nonalcoholic fatty liver disease in Zhangzhou city [article in Chinese]. J Chin Phys 2012; 14:268-270.
25. Tung T, Chiu W, Lin T, Shih H, Hsu C. An exploration of prevalence and associated factors of nonalcoholic fatty liver disease in the Taiwanese police service. Iran J Public Health 2011; 40:54-62.
26. Wang J, Chiu WH , Chen RC, Chen FL, Tung TH. The clinical investigation of disparity of nonalcoholic fatty liver disease in a Chinese occupational population in Taipei, Taiwan: experience at a teaching hospital. Asia Pac J Public Health 2015; 27:1793-1804.
27. Zhang H, Gong Y, Ni X, Shen H. Studies on prevalence and risk factors of non-Alcoholic fatty liver disease among Nantong health check-up subjects [article in Chinese]. China Modern Doctor 2012; 50:23-26.
28. Xie Y, Wang M, Zhang Y, Zhang S, Tan A, Gao Y, et al. Serum uric acid and non-Alcoholic fatty liver disease in non-diabetic Chinese men. PLoS One 2013; 8:e67152.
29. Sirota JC, McFann K, Targher G, Johnson RJ, Chonchol M, Jalal DI. Elevated serum uric acid levels are associated with non-Alcoholic fatty liver disease independently of metabolic syndrome features in the United States: liver ultrasound data from the national health and nutrition examination survey. Metabolism 2013; 62:392-399.
30. Xia MF, Lin HD, Li XM, Yan HM, Bian H, Chang XX, et al. Renal functio ndependent association of serum uric acid with metabolic syndrome and hepatic fat content in a middle-Aged and elderly Chinese population. Clin Exp Pharmacol Physiol 2012; 39:930-937.
31. Hwang IC, Suh SY, Suh AR, Ahn HY. The relationship between normal serum uric acid and nonalcoholic fatty liver disease. J Korean Med Sci 2011; 26:386-391.
32. Yamada T, Suzuki S, Fukatsu M, Wada T, Yoshida T, Joh T. Elevated serum uric acid is an independent risk factor for nonalcoholic fatty liver disease in Japanese undergoing a health checkup. Acta Gastroenterol Belg 2010; 73:12-1 7.
33. Xu C, Yu C, Xu L, Miao M, Li Y. High serum uric acid increases the risk for nonalcoholic fatty liver disease: a prospective observational study. PLoS One 2010; 5:e11578.
34. Lee YJ, Lee HR, Lee JH, Shin YH, Shim JY. Association between serum uric acid and non-Alcoholic fatty liver disease in Korean adults. Clin Chem Lab Med 2010; 48:175-180.
35. Lee JW,Cho YK,Ryan M,Kim H,Lee SW,Chang E,et al. Serum uric acid as a predictor for the development of nonalcoholic fatty liver disease in apparently healthy subjects: a 5-year retrospective cohort study Gut Liver 2010 4 378-383.
36. Kuo CF, Yu KH, Luo SF, Chiu CT, Ko YS, Hwang JS, et al. Gout and risk of non-Alcoholic fatty liver disease. Scand J Rheumatol 2010; 39:466-471.
37. Xu C, Yu C, Ma H, Xu L, Miao M, Li Y. Prevalence and risk factors for the development of nonalcoholic fatty liver disease in a nonobese Chinese population: the Zhejiang Zhenhai study. Am J Gastroenterol 2013; 108:1299-1304.
38. Moon SS. Relationship between serum uric acid level and nonalcoholic fatty liver disease in pre-And postmenopausal women. Ann Nutr Metab 2013; 62:158-163.
39. Qiu L, Cheng XQ, Wu J, Liu JT, Xu T, Ding HT, et al. Prevalence of hyperuricemia and its related risk factors in healthy adults from northern and northeastern Chinese provinces. BMC Public Health 2013; 13:664.
40. Baldwin W, McRae S, Marek G, Wymer D, Pannu V, Baylis C, et al. Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome. Diabetes 2011; 60:1258-1269.
41. Wasilewska A, Tenderenda E, Taranta-Janusz K, Tobolczyk J, Stypulkowska J. Markers of systemic inflammation in children with hyperuricemia. Acta Paediatr 2012; 101:497-500.
42. Sung KC, Kim SH. Interrelationship between fatty liver and insulin resistance in the development of type 2 diabetes. J Clin Endocrinol Metab 2011; 96:1093-1097.
43. Sanchez-Lozada LG, Soto V, Tapia E, Avila-Casado C, Sautin YY, Nakagawa T, et al. Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia. Am J Physiol Rena l Physiol 2008; 295:F1134-F1141.
44. Tariq Z, Green CJ, Hodson L. Are oxidative stress mechanisms the common denominator in the progression from hepatic steatosis towards non-Alcoholic steatohepatitis (NAS H)? Liver Int 2014; 34: 180-190.