A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ42

Alzheimer's and Dementia

Volumn 11, Issue 12, 2015, Pages 1452-1460

  Sleegers, Kristel ^a,b   Bettens, Karolien ^a,b   De Roeck, Arne ^a,b   Van Cauwenberghe, Caroline ^a,b   Cuyvers, Elise ^a,b   Verheijen, Jan ^a,b   Struyfs, Hanne ^b   Van Dongen, Jasper ^a,b   Vermeulen, Steven ^a,b   Engelborghs, Sebastiaan ^b,c   Vandenbulcke, Mathieu ^d   Vandenberghe, Rik ^d   De Deyn, Peter Paul ^b,c,e   Van Broeckhoven, Christine ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c Hospital Network Antwerp Middelheim and Hoge Beuken   (Belgium)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Alzheimer's disease; CSF A 1 42; Family history; Genetic risk profile; Genotype phenotype correlation; Onset age

Indexed keywords

ABCA7 PROTEIN; AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN E; BIN1 PROTEIN; CASS4 PROTEIN; CD2 ASSOCIATED PROTEIN; CD33 ANTIGEN; CELF1 PROTEIN; CLU PROTEIN; CR1 PROTEIN; EPHRIN RECEPTOR A1; FERMT2 PROTEIN; HLA DRB5 ANTIGEN; INPP5D PROTEIN; MS4A6A PROTEIN; NME8 PROTEIN; PEPTIDES AND PROTEINS; PICALM PROTEIN; PTK2B PROTEIN; SLC24A4 PROTEIN; SORL1 PROTEIN; TAU PHOSPHORYLATED AT THREONINE 181 PROTEIN; TAU PROTEIN; TOTAL TAU PROTEIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG; ZCWPW1 PROTEIN; AMYLOID BETA PROTEIN; BIOLOGICAL MARKER; PEPTIDE FRAGMENT;

AGED; ALZHEIMER DISEASE; AREA UNDER THE CURVE; ARTICLE; ASSESSMENT OF HUMANS; CEREBROSPINAL FLUID; CONTROLLED STUDY; DISEASE PREDISPOSITION; FAMILY HISTORY; FEMALE; GENETIC RISK; GENETIC RISK SCORE; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; BELGIUM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; MIDDLE AGED; PHENOTYPE; RISK FACTOR;

AGE OF ONSET; AGED; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APOLIPOPROTEINS E; BELGIUM; BIOMARKERS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PEPTIDE FRAGMENTS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; TAU PROTEINS;

EID: 84952630745     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2015.02.013     Document Type: Article

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