Comparative study of the neuroprotective and nootropic activities of the carboxylate and amide forms of the HLDF-6 peptide in animal models of Alzheimer's disease

Journal of Psychopharmacology

Volumn 30, Issue 1, 2016, Pages 78-92

  Bogachouk, Anna P ^a   Storozheva, Zinaida I ^b   Solovjeva, Olga A ^c   Sherstnev, Vyacheslav V ^c   Zolotarev, Yury A ^d   Azev, Vyacheslav N ^a   Rodionov, Igor L ^a   Surina, Elena A ^a   Lipkin, Valery M ^a  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^b Federal Medical Research Centre of Psychiatry and Narcology   (Russian Federation)

^c P K ANOKHIN INSTITUTE OF NORMAL PHYSIOLOGY   (Russian Federation)

^d INSTITUTE OF MOLECULAR GENETICS   (Russian Federation)

Author keywords

Alzheimer's disease (AD); beta amyloid fragment 25 35 ( A 25 35); HLDF 6 peptide; Human leukemia differentiation factor (HDLF); neuroprotection; nootropic activity

Indexed keywords

AMIRIDINE; AMYLOID BETA PROTEIN[25-35]; HUMAN LEUKEMIA DIFFERENTIATION FACTOR 6 PEPTIDE; IBOTENIC ACID; PEPTIDE; UNCLASSIFIED DRUG; AMIDE; CARBOXYLIC ACID; NEUROPROTECTIVE AGENT; NOOTROPIC AGENT; OLIGOPEPTIDE; THREONYL-GLYCYL-GLUTAMYL-ASPARAGINYL-HISTIDYLARGININE;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITION; COGNITIVE DEFECT; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG HALF LIFE; DRUG TRANSFORMATION; GIANT CELL; HIPPOCAMPUS; MALE; MEYNERT BASAL NUCLEUS; MORRIS WATER MAZE TEST; NEUROPROTECTION; NONHUMAN; NOOTROPIC ACTIVITY; NOVEL OBJECT RECOGNITION TEST; PASSIVE AVOIDANCE TEST; PRIORITY JOURNAL; RAT; ANIMAL; AVOIDANCE BEHAVIOR; CHEMISTRY; COGNITION DISORDERS; DISEASE MODEL; DRUG EFFECTS; MAZE TEST; PATHOPHYSIOLOGY; WISTAR RAT;

ALZHEIMER DISEASE; AMIDES; ANIMALS; AVOIDANCE LEARNING; CARBOXYLIC ACIDS; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; MALE; MAZE LEARNING; NEUROPROTECTIVE AGENTS; NOOTROPIC AGENTS; OLIGOPEPTIDES; RATS; RATS, WISTAR;

EID: 84952052984     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881115616393     Document Type: Article

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