Different effects on learning ability after injection of the cholinergic immunotoxin ME20.4IgG-saporin into the diagonal band of Broca, basal nucleus of Meynert, or both in monkeys

Behavioral Neuroscience

Volumn 113, Issue 2, 1999, Pages 303-315

  Ridley, R M ^a,b   Barefoot, H C ^a   Maclean, C J ^a   Pugh, P ^a   Baker, H F ^a  

^a UK   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; DIZOCILPINE; GLUTAMATE RECEPTOR ANTAGONIST; IMMUNOGLOBULIN G; IMMUNOTOXIN; SAPORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX LESION; CHOLINERGIC NERVE; CONDITIONING; CONTROLLED STUDY; DISCRIMINATION LEARNING; FEMALE; FOREBRAIN; HIPPOCAMPUS; IMMUNOTOXICITY; LEARNING DISORDER; MALE; MARMOSET; NONHUMAN; PERCEPTION DISORDER; PYRAMIDAL NERVE CELL; TASK PERFORMANCE; VISUAL DISCRIMINATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN INJURIES; CALLITHRIX; CHOLINERGIC AGENTS; COGNITION; DISCRIMINATION LEARNING; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; FRONTAL LOBE; GLUTAMATES; IMMUNOTOXINS; MALE; N-GLYCOSYL HYDROLASES; RECOVERY OF FUNCTION; VISUAL PERCEPTION;

EID: 0032897540     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.113.2.303     Document Type: Article

References (47)

1. Baker, H. F., & Ridley, R. M. (1986). Use of the common marmoset (Callithrix jacchus) in psychopharmacological research. In M. H. Joseph & L. J. Waddington (Eds.), Working methods in neuropsychopharmacological research (pp. 41-73). Manchester, England: Manchester University Press.
2. Baxter, M. G., Bucci, D. J., Gorman, L. K., Wiley, R. G., & Gallagher, M. (1995). Selective immunotoxic lesions of basal forebrain cholinergic cells: Effects on learning and memory in rats. Behavioral Neuroscience, 109, 714-722.
3. Baxter, M. G., Bucci, D. J., Sobel, T. J., Williams, M. J., Gorman, L. K., & Gallagher, M. (1996). Intact spatial learning following lesions of the basal forebrain cholinergic neurons. NeuroReport, 7, 1417-1420.
4. Berger-Sweeney, J., Heckers, S., Mesulam, M.-M., Wiley, R. G., Lappi, D. A., & Sharma, M. (1994). Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis. Journal of Neuroscience, 14, 4507-4519.
5. Book, A. A., Wiley, R. G., & Schwietzer, J. B. (1992). Specificity of 192 IgG-saporin for NGF receptor-positive cholinergic basal forebrain neurons in the rat. Brain Research, 590, 350-355.
6. Dean, P. (1976). Effects of inferotemporal lesions on the behavior of monkeys. Psychological Bulletin, 83, 41-71.
7. Dornan, W. A., McCampbell, A. R., Tinkler, G. P., Hickman, L. J., Bannon, A. W., Decker, M. W., & Gunther, K. L. (1996). Comparison of site-specific injections into the basal forebrain on water maze and radial arm maze performance in the male rat after immunolesioning with 192 IgG saporin. Behavioural Brain Research, 82, 93-101.
8. Fine, A., Hoyle, C., Maclean, C. J., LeVatte, T. L., Baker, H. F., & Ridley, R. M. (1997). Learning impairments following injection of a selective cholinergic immunotoxin, ME20.4 IgG-saporin, into the basal nucleus of Meynert in monkeys. Neuroscience, 81, 331-343.
9. Francis, P. T., Cross, A. J., & Bowen, D. M. (1994). Neurotransmitters and neuropeptides. In R. D. Terry, R. Katzman, & K. L. Bick (Eds.), Alzheimer disease (pp. 247-261). New York: Raven Press.
10. Gaffan, D., & Harrison, S. (1989). Place memory and scene memory: Effects of fornix transection in the monkey. Experimental Brain Research, 74, 202-212.
11. Gross, C. G. (1973). Visual functions of inferotemporal cortex. In R. Jung (Ed.), Handbook of sensory physiology (Vol 7, Part 3B, pp. 451-482). Berlin: Springer-Verlag.
12. Harder, J. A., Aboobaker, A., Hodgetts, T., Hoyle, C., & Ridley, R. M. (1998). Learning impairment induced by glutamate blockade using dizocilpine (MK801) in monkeys. British Journal of Pharmacology, 125, 1013-1018.
13. Harder, J. A., Baker, H. F., & Ridley, R. M. (1998). The role of the central cholinergic projections in cognition: Implications of the effects of scopolamine on discrimination learning by monkeys. Brain Research Bulletin, 45, 319-326.
14. 1A antagonist, WAY100635, ameliorates the cognitive impairment induced by fornix transection in the marmoset. Psychopharmacology, 127, 245-254.
15. Jones, B., & Mishkin, M. (1972). Limbic lesions and the problem of stimulus reinforcement associations. Experimental Neurology, 36, 362-377.
16. Koelle, G. B. (1955). The histochemical identification of acetylcholinesterase in cholinergic, adrenergic and sensory neurons. Journal of Pharmacology and Experimental Therapeutics, 114, 167-184.
17. Leanza, G., Nilsson, O. G., Wiley, R. G., & Björklund, A. (1995). Selective lesioning of the basal forebrain cholinergic system by intraventricular 192IgG-saporin: behavioural, biochemical and stereological studies in the rat. European Journal of Neuroscience, 7, 329-343.
18. Maclean, C. J., Baker, H. F., Fine, A., & Ridley, R. M. (1997). The distribution of p75 neurotrophin receptor-immunoreactive cells in the forebrain of the common marmoset (Callithrix jacchus). Brain Research Bulletin, 43, 197-208.
19. Mahut, H. (1971). Spatial and object reversal learning in monkeys with partial temporal lobe ablations. Neuropsychologia, 9, 409-424.
20. Mesulam, M.-M., Mufson, E. J., Levey, A. I., & Wainer, B. H. (1983). Cholinergic innervation of cortex by the basal forebrain: Cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata) and hypothalamus in the rhesus monkey. Journal of Comparative Neurology, 214, 170-197.
21. Mesulam, M.-M., Mufson, E. J., Levey, A. I., & Wainer, B. H. (1984). Atlas of cholinergic neurons in the forebrain and upper brainstem of the macaque based on monoclonal choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Neuroscience, 3, 669-686.
22. Mesulam, M.-M., & Van Hoesen, G. W. (1976), Acetylcholinesterase-rich projections from the basal forebrain of the rhesus monkey to neocortex. Brain Research, 109, 152-157.
23. Murray, T. K., & Ridley, R. M. (1997). The effect of dizocilpine (MK801) on conditional discrimination learning in the rat. Behavioural Pharmacology, 8, 383-388.
24. Murray, T. K., Ridley, R. M., Snape, M. F., & Cross, A. J. (1995). The effect of dizocilpine (MK801) on spatial and visual discrimination tasks in the rat. Behavioural Pharmacology, 6, 1-10.
25. Nilsson, O. G., Leanza, G., Rosenblad, C., Lappi, D. A., Wiley, R. G., & Björklund, A. (1992). Spatial learning impairments in rats with selective immunolesion of the forebrain cholinergic system. NeuroReport, 3, 1005-1008.
26. Ridley, R. M., Aitken, D. M., & Baker, H. F. (1989). Learning about rules but not about reward is impaired following lesions of the cholinergic projection to the hippocampus. Brain Research, 502, 306-318.
27. Ridley, R. M., & Baker, H. F. (1991). A critical evaluation of monkey models of amnesia and dementia. Brain Research Reviews, 16, 15-37.
28. Ridley, R. M., & Baker, H. F. (1997). Evidence for a specific information processing deficit in monkeys with lesions of the septo-hippocampal system. Cortex, 33, 167-176.
29. Ridley, R. M., Baker, J. A., Baker, H. F., & Maclean, C. J. (1994). Restoration of cognitive abilities by cholinergic grafts in cortex of monkeys with lesions of the basal nucleus of Meynert. Neuroscience, 63, 653-666.
30. Ridley, R. M., Baker, H. F., Drewett, B., & Johnson, J. A. (1985). Effects of ibotenic acid lesions of the basal forebrain on serial reversal learning in marmosets. Psychopharmacology, 86, 438-443.
31. Ridley, R. M., Baker, H. F., Harder, J. A., & Pearson, C. (1996). Effects of lesions of different parts of the septo-hippocampal system in primates on learning and retention of information acquired before or after surgery. Brain Research Bulletin, 40, 21-32.
32. Ridley, R. M., Clark, B. A., Dumford, L. J., & Baker, H. F. (1993). Stimulus-bound perseveration after frontal ablations in marmosets. Neuroscience, 52, 595-604.
33. Ridley, R. M., Durnford, L. J., Baker, J. A., & Baker, H. F. (1993). Cognitive inflexibility after archicortical and paleocortical prefrontal lesions in marmosets. Brain Research, 628, 56-64.
34. Ridley, R. M., Gribble, S., Clark, B., Baker, H. F., & Fine, A. (1992). Restoration of learning ability in fornix-transected monkeys after fetal basal forebrain but not fetal hippocampal tissue transplantation. Neuroscience, 48, 779-792.
35. Ridley, R. M., Murray, T. K., Johnson, J. A., & Baker, H. F. (1986). Learning impairment following lesion of the basal nucleus of Meynert in the marmoset: Modification by cholinergic drugs. Brain Research, 376, 108-116.
36. Ridley, R. M., Pearson, C., Kershaw, T. R., Hodges, H., Maclean, C. J., Hoyle, C., & Baker, H. F. (1996). Learning impairment induced by lesion of the CA1 field of the primate hippocampus: Attempts to ameliorate the impairment by transplantation of fetal CA1 tissue. Experimental Brain Research, 115, 83-94.
37. Ridley, R. M., Samson, N. A., Baker, H. F., & Johnson, J. A. (1988). Visuospatial learning impairment following lesion of the cholinergic projection to the hippocampus. Brain Research, 456, 71-87.
38. Ridley, R. M., Thornley, H. D., Baker, H. F., & Fine, A. (1991). Cholinergic neural transplants into hippocampus restore learning ability in monkeys with fornix transections. Experimental Brain Research, 83, 533-538.
39. Ridley, R. M., Timothy, C. J., Maclean, C. J., & Baker, H. F. (1995). Conditional learning and memory impairments following neurotoxic lesion of the CA1 field of the hippocampus. Neuroscience, 67, 263-275.
40. Stamm, J. S. (1973). Functional dissociation between the inferior and arcuate segments of dorsolateral prefrontal cortex in the monkey. Neuropsychologia, 11, 181-190.
41. Stephan, H., Baron, G., & Schwerdtfeger, W. K. (1980). The brain of the common marmoset (Callithrix jacchus) a stereotaxic atlas. Berlin: Springer.
42. Torres, E. M., Perry, T. A., Blokland, A., Wilkinson, L. S., Wiley, R. G., Lappi, D. A., & Dunnett, S. B. (1994). Behavioural, histochemical and biochemical consequences of selective immunolesions in discrete regions of the basal forebrain cholinergic system. Neuroscience, 63, 59-122.
43. Waite, J. J., Chen, A. D., Wardlow, M. L., Wiley, R. G., Lappi, D. A., & Thai, L. J. (1995). 192 Immunoglobulin G-saporin produces graded behavioral and biochemical changes accompanying the loss of cholinergic neurons of the basal forebrain and cerebellar Purkinje cells. Neuroscience, 65, 463-476.
44. Wenk, G. L., Stoehr, J. D., Quintana, G., Mobley, S., & Wiley, R. G. (1994). Behavioral, biochemical, histological, and electrophysiological effects of 192 IgG-saporin injections into the basal forebrain of rats. Journal of Neuroscience, 14, 5986-5995.
45. Wong, E. H. F., Kemp, J. A., Priestly, T., Knight, A. R., Woodruff, G. N., & Iversen, L. L. (1986). The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proceedings of the National Academy of Sciences of the United States of America, 83, 7104-7108.
46. Zola-Morgan, S., & Squire, L. R. (1985). Medial temporal lesions in monkeys impair memory in a variety of tasks sensitive to human amnesia. Behavioral Neuroscience, 99, 22-34.
47. Zola-Morgan, S., Squire, L. R., & Amaral, D. G. (1989). Lesions of the hippocampal formation but not lesions of the fornix or the mammillary nuclei produce long-lasting memory impairment in monkeys. Journal of Neuroscience, 9, 898-913.