Population genetic testing for cancer susceptibility: Founder mutations to genomes

Nature Reviews Clinical Oncology

Volumn 13, Issue 1, 2016, Pages 41-54

  Foulkes, William D ^a   Knoppers, Bartha Maria ^a,b   Turnbull, Clare ^c,d  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CHECKPOINT KINASE 2; DNA GLYCOSYLASE MUTY; TUMOR MARKER;

BREAST CANCER; CANCER SUSCEPTIBILITY; CHEK2 GENE; COST BENEFIT ANALYSIS; COST EFFECTIVENESS ANALYSIS; FAMILY HISTORY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC COUNSELING; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HETEROZYGOTE; HUMAN; MUTYH GENE; NEWBORN SCREENING; ONCOGENE; OVARY CANCER; PATIENT SELECTION; PHYSICIAN ATTITUDE; POPULATION GENETICS; PRIORITY JOURNAL; REVIEW; TUMOR SUPPRESSOR GENE; VALIDATION PROCESS; BLOOD; BREAST TUMOR; DNA SEQUENCE; FEMALE; FOUNDER EFFECT; GENETIC PREDISPOSITION; GENETICS; HUMAN GENOME; MASS SCREENING; MUTATION; NEOPLASMS; OVARY TUMOR; PROCEDURES; RISK ASSESSMENT;

BIOMARKERS, TUMOR; BREAST NEOPLASMS; FEMALE; FOUNDER EFFECT; GENES, BRCA1; GENES, BRCA2; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GENOME, HUMAN; HUMANS; MASS SCREENING; MUTATION; NEOPLASMS; OVARIAN NEOPLASMS; RISK ASSESSMENT; SEQUENCE ANALYSIS, DNA;

EID: 84951906736     PISSN: 17594774     EISSN: 17594782     Source Type: Journal    
DOI: 10.1038/nrclinonc.2015.173     Document Type: Review

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