Family history of cancer and cancer risks in women with BRCA1 or BRCA2 mutations

Journal of the National Cancer Institute

Volumn 102, Issue 24, 2010, Pages 1874-1878

  Metcalfe, Kelly ^a,b   Lubinski, Jan ^c   Lynch, Henry T ^d   Ghadirian, Parviz ^e   Foulkes, William D ^f   Kim Sing, Charmaine ^g   Neuhausen, Susan ^h   Tung, Nadine ⁱ   Rosen, Barry ^j   Gronwald, Jacek ^c   Ainsworth, Peter ^k   Sweet, Kevin ^l   Eisen, Andrea ^m   Sun, Ping ^a   Narod, Steven A ^a  

^a WOMEN S COLLEGE HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c POMERANIAN MEDICAL UNIVERSITY   (Poland)

^d CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

^f MCGILL UNIVERSITY   (Canada)

^g BRITISH COLUMBIA CANCER AGENCY   (Canada)

^h City of Hope ^*  (United States)

ⁱ BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^j UNIVERSITY HEALTH NETWORK   (Canada)

^k LONDON REGIONAL CANCER PROGRAM   (Canada)

^l OHIO STATE UNIVERSITY   (United States)

^m DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER INCIDENCE; CANCER RISK; CANCER SUSCEPTIBILITY; COHORT ANALYSIS; CONFIDENCE INTERVAL; FAMILY HISTORY; FEMALE; FOLLOW UP; GENE MUTATION; HAZARD RATIO; HUMAN; OVARY CANCER; PRIORITY JOURNAL; PROSPECTIVE STUDY; RELATIVE;

ADULT; AGE FACTORS; AGED; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; COHORT STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HUMANS; MIDDLE AGED; MUTATION; ODDS RATIO; OVARIAN NEOPLASMS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS;

EID: 78650409243     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djq443     Document Type: Article

References (5)

1. Claus EB, Risch NJ, Thompson WD. Age at onset as an indicator of familial risk of breast cancer. Am J Epidemiol. 1990;131(6):961-972.
2. Cancer Collaborative Group on Hormonal Factors in Breast Cancer. Familial breast cancer: collaborative reanalysis of individual data from 52 epidemiological studies including 58 209 women with breast cancer and 101 986 women without the disease. Lancet. 2001;358:1389-1399.
3. Antoniou A, Pharoah PD, Narod S, et al. Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies. Am J Hum Genet. 2003;72(5):1117-1130.
4. Simchoni S, Friedman E, Kaufman B, et al. Familial clustering of site-specifc cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population. Proc Natl Acad Sci USA. 2006;103(10):3770-3774.
5. Moslehi R, Chu W, Karlan B, et al. BRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer. Am J Hum Genet. 2000;66(4):1259-1272.