Swelling and drug release behavior of metformin HCl-loaded tamarind seed polysaccharide-alginate beads

International Journal of Biological Macromolecules

Volumn 82, Issue , 2016, Pages 1023-1027

  Nayak, Amit Kumar ^a   Pal, Dilipkumar ^b   Santra, Kousik ^a  

^a SEEMANTA INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

^b GURU GHASIDAS UNIVERSITY   (India)

Author keywords

Ionotropic gelation; Sodium alginate; Tamarind seed polysaccharide

Indexed keywords

ALGINIC ACID; CALCIUM CHLORIDE; METFORMIN; POLYSACCHARIDE; ANTIDIABETIC AGENT; DRUG CARRIER; GLUCURONIC ACID; HEXURONIC ACID; MICROSPHERE; PLANT EXTRACT;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG SYNTHESIS; ENCAPSULATION; GELATION; IN VITRO STUDY; INFRARED SPECTROSCOPY; MOLECULAR INTERACTION; NONHUMAN; PARTICLE SIZE; PH; PLANT SEED; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TAMARIND; CHEMISTRY; DRUG RELEASE; MEDICINAL CHEMISTRY; ULTRASTRUCTURE;

ALGINATES; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG LIBERATION; GLUCURONIC ACID; HEXURONIC ACIDS; HYPOGLYCEMIC AGENTS; METFORMIN; MICROSPHERES; PLANT EXTRACTS; POLYSACCHARIDES; SEEDS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84951791931     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2015.10.027     Document Type: Article

References (34)

1. Pal D., Mitra S. A preliminary study on the in vitro antioxidant activity of the stems of Opuntia vulgaris. J. Adv. Pharm. Technol. Res. 2010, 1:172-268.
2. Nayak A.K., Pal D., Pany D.R., Mohanty B. Evaluation of Spinacia oleracea L. leaves mucilage as innovative suspending agent. J. Adv. Pharm. Technol. Res. 2010, 1:338-341.
3. Nayak A.K., Pal D., Pradhan J., Ghorai T. The potential of Trigonella foenum-graecum L. seed mucilage as suspending agent. Indian J. Pharm. Educ. Res. 2012, 46:312-317.
4. Pal D., Banerjee S., Ghosh A.K. Dietary-induced cancer prevention: an expanding research arena of emerging diet related to healthcare system. J. Adv. Pharm. Technol. Res. 2012, 3:16-24.
5. Nayak A.K., Pal D., Santra K. Screening of polysaccharides from tamarind, fenugreek and jackfruit seeds as pharmaceutical excipients. Int. J. Biol. Macromol. 2015, 79:756-760.
6. Nayak A.K., Pal D., Santra K. Development of pectinate-ispagula mucilage mucoadhesive beads of metformin HCl by central composite design. Int. J. Biol. Macromol. 2014, 66:203-221.
7. Nayak A.K., Pal D., Santra K. Development of calcium pectinate-tamarind seed polysaccharide mucoadhesive beads containing metformin HCl. Carbohydr. Polym. 2014, 101:220-230.
8. Racovita S., Vasilu S., Popa M., Luca C. Polysaccharides based micro- and nanoparticles obtained by ionic gelation and their applications as drug delivery systems. Rev. Roum. Chim. 2009, 54:709-718.
9. Al-Kassas R., Al-Gohary O.M.N., Al-Fadhel M.M. Controlling of systemic absorption of gliclazide through incorporation into alginate beads. Int. J. Pharm. 2007, 341:230-237.
10. Babu R.J., Sathigrahi S., Kumar M.T., Pandit J.K. Formulation of controlled release gellan gum macro beads of amoxicillin. Curr. Drug Deliv. 2010, 7:36-43.
11. Lee J.-S., Chung D., Lee H.G. Optimization of calcium pectinate gel beads for sustained-release of catechin using response surface methodology. Int. J. Biol. Macromol. 2008, 42:340-347.
12. Ahuja M., Yadav M., Kumar S. Application of response surface methodology to formulation of ionotropically gelled gum cordial/gellan beads. Carbohydr. Polym. 2010, 80:161-167.
13. Nayak A.K., Das B., Maji R. Calcium alginate/gum Arabic beads containing glibenclamide: development and in vitro characterization. Int. J. Biol. Macromol. 2012, 51:1070-1078.
14. Nayak A.K., Pal D. Blends of jackfruit seed starch-pectin in the development of mucoadhesive beads containing metformin HCl. Int. J. Biol. Macromol. 2013, 62:137-145.
15. Nayak A.K., Pal D. Formulation optimization of jackfruit seed starch-alginate mucoadhesive beads of metformin HCl. Int. J. Biol. Macromol. 2013, 59:264-272.
16. Nayak A.K., Pal D., Santra K. Artocarpus heterophyllus L. seed starch-blended gellan gum mucoadhesive beads of metformin HCl. Int. J. Biol. Macromol. 2014, 65:329-339.
17. Nayak A.K., Hasanin M.S., Beg S., Alam M.I. Mucoadhesive beads of gliclazide: design, development, and evaluation. Sci. Asia 2010, 36:319-325.
18. Nayak A.K., Pal D., Santra K. Plantago ovata F. mucilage-alginate mucoadhesive beads for controlled release of glibenclamide: development, optimization and in vitro-in vivo evaluation. J. Pharm. 2013, 2013. Article ID 151035.
19. Nayak A.K., Pal D., Pradhan J., Hasnain M.S. Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: design, optimization and evaluation. Int. J. Biol. Macromol. 2013, 54:144-154.
20. Nayak A.K., Pal D. Development of pH-sensitive tamarind seed polysaccharide-alginate composite beads for controlled diclofenac sodium delivery using response surface methodology. Int. J. Biol. Macromol. 2011, 49:784-793.
21. Sinha P., Ubaidulla U., Nayak A.K. Okra (Hibiscus esculentus) gum-alginate blend mucoadhesive beads for controlled glibenclamide release. Int. J. Biol. Macromol. 2015, 72:1069-1075.
22. 4 as a cross-linker. Int. J. Biol. Macromol. 2015, 79:555-563.
23. Pal D., Nayak A.K. Novel tamarind seed polysaccharide-alginate mucoadhesive microspheres for oral gliclazide delivery: in vitro-in vivo evaluation. Drug Deliv. 2012, 19:123-131.
24. Nayak A.K., Pal D. Ionotropically-gelled mucoadhesive beads for oral metformin HCl delivery: formulation, optimization and antidiabetic evaluation. J. Sci. Ind. Res. 2013, 72:15-22.
25. Pal D., Nayak A.K. Development, optimization and anti-diabetic activity of gliclazide-loaded alginate-methyl cellulose mucoadhesive microcapsules. AAPS PharmSciTech 2011, 12:1431-1441.
26. 3+ ion cross-linked interpenetrating polymeric network microbeads from tailored natural polysaccharides. Int. J. Biol. Macromol. 2012, 51:1173-1184.
27. Mendyk A., Jachowicz R., Fijorek K., Dorozynski P., Kulinowski P., Polak S. KinetDS: an open source software for dissolution test analysis. Dissol. Technol. 2012, 19:6-11.
28. Kaur H., Yadav S., Ahuja M., Dilbaghi N. Synthesis, characterization and evaluation of thiolated tamarind seed polysaccharide as a mucoadhesive polymer. Carbohydr. Polym. 2012, 90:1543-1549.
29. Jana S., Lakshman D., Sen K.K., Basu S.K. Development and evaluation of epichlorohydrin cross-linked mucoadhesive patches of tamarind seed polysaccharide for buccal application. Int. J. Pharm. Sci. Drug Res. 2010, 2:193-198.
30. Joseph J., Kanchalochana S.N., Rajalakshmi G., Hari V., Durai R.D. Tamarind seed polysaccharide: a promising natural excipients for pharmaceuticals. Int. J. Green Pharm. 2012, 6:270-278.
31. Jana S., Saha A., Nayak A.K., Sen K.K., Basu S.K. Aceclofenac-loaded chitosan-tamarind seed polysaccharide interpenetrating polymeric network microparticles. Colloids Surf. B: Biointerface 2013, 105:303-309.
32. Nayak A.K., Pal D., Santra K. Tamarind seed polysaccharide-gellan mucoadhesive beads for controlled release of metformin HCl. Carbohyr. Polym. 2014, 103:154-163.
33. Sujja-areevath J., Munday D.L., Cox P.J., Khan K.A. Relationship between swelling, erosion and drug release in hydrophillic natural gum mini-matrix formulations. Eur. J. Pharm. Sci. 1998, 6:207-217.
34. Pasparakis G., Bouropoulos N. Swelling studies and in vitro release of verapamil from calcium alginate and calcium alginate-chitosan beads. Int. J. Pharm. 2006, 323:34-42.