-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011; 61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
3
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001; 414:105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
4
-
-
84856501335
-
The developing cancer stem-cell model: clinical challenges and opportunities
-
Vermeulen L, de Sousa e Melo F, Richel DJ, Medema JP. The developing cancer stem-cell model: clinical challenges and opportunities. Lancet Oncol. 2012; 13:e83-89.
-
(2012)
Lancet Oncol
, vol.13
, pp. e83-e89
-
-
Vermeulen, L.1
de Sousae Melo, F.2
Richel, D.J.3
Medema, J.P.4
-
5
-
-
77956178360
-
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
-
Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene. 2010; 29:4741-4751.
-
(2010)
Oncogene
, vol.29
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
6
-
-
6344255055
-
A proposal for the physiological significance of mdr1 and Bcrp1/Abcg2 gene expression in normal tissue regeneration and after cancer therapy
-
Israeli D, Ziaei S, Gonin P, Garcia L. A proposal for the physiological significance of mdr1 and Bcrp1/Abcg2 gene expression in normal tissue regeneration and after cancer therapy. J Theor Biol. 2005; 232:41-45.
-
(2005)
J Theor Biol
, vol.232
, pp. 41-45
-
-
Israeli, D.1
Ziaei, S.2
Gonin, P.3
Garcia, L.4
-
7
-
-
83555172386
-
Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness
-
Joshua B, Kaplan MJ, Doweck I, Pai R, Weissman IL, Prince ME, Ailles LE. Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness. Head Neck. 2012; 34:42-49.
-
(2012)
Head Neck
, vol.34
, pp. 42-49
-
-
Joshua, B.1
Kaplan, M.J.2
Doweck, I.3
Pai, R.4
Weissman, I.L.5
Prince, M.E.6
Ailles, L.E.7
-
8
-
-
84917691199
-
Targeting the c-Met/FZD8 signaling axis eliminates patient-derived cancer stem-like cells in head and neck squamous carcinomas
-
Sun S, Liu S, Duan SZ, Zhang L, Zhou H, Hu Y, Zhou X, Shi C, Zhou R, Zhang Z. Targeting the c-Met/FZD8 signaling axis eliminates patient-derived cancer stem-like cells in head and neck squamous carcinomas. Cancer Res. 2014; 74:7546-7559.
-
(2014)
Cancer Res
, vol.74
, pp. 7546-7559
-
-
Sun, S.1
Liu, S.2
Duan, S.Z.3
Zhang, L.4
Zhou, H.5
Hu, Y.6
Zhou, X.7
Shi, C.8
Zhou, R.9
Zhang, Z.10
-
9
-
-
84908161000
-
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
-
Yu H, Lee H, Herrmann A, Buettner R, Jove R. Revisiting STAT3 signalling in cancer: new and unexpected biological functions. Nat Rev Cancer. 2014; 14:736-746.
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 736-746
-
-
Yu, H.1
Lee, H.2
Herrmann, A.3
Buettner, R.4
Jove, R.5
-
10
-
-
34250658084
-
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity
-
Siddiquee K, Zhang S, Guida WC, Blaskovich MA, Greedy B, Lawrence HR, Yip ML, Jove R, McLaughlin MM, Lawrence NJ, Sebti SM, Turkson J. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity. Proc Natl Acad Sci U S A. 2007; 104:7391-7396.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 7391-7396
-
-
Siddiquee, K.1
Zhang, S.2
Guida, W.C.3
Blaskovich, M.A.4
Greedy, B.5
Lawrence, H.R.6
Yip, M.L.7
Jove, R.8
McLaughlin, M.M.9
Lawrence, N.J.10
Sebti, S.M.11
Turkson, J.12
-
11
-
-
77950391697
-
Stat3 orchestrates tumor development and progression: the Achilles' heel of head and neck cancers?
-
Masuda M, Wakasaki T, Suzui M, Toh S, Joe AK, Weinstein IB. Stat3 orchestrates tumor development and progression: the Achilles' heel of head and neck cancers?. Curr Cancer Drug Targets. 2010; 10:117-126.
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 117-126
-
-
Masuda, M.1
Wakasaki, T.2
Suzui, M.3
Toh, S.4
Joe, A.K.5
Weinstein, I.B.6
-
12
-
-
84922601431
-
WP1066 sensitizes oral squamous cell carcinoma cells to cisplatin by targeting STAT3/miR-21 axis
-
Zhou X, Ren Y, Liu A, Jin R, Jiang Q, Huang Y, Kong L, Wang X, Zhang L. WP1066 sensitizes oral squamous cell carcinoma cells to cisplatin by targeting STAT3/miR-21 axis. Sci Rep. 2014; 4:7461.
-
(2014)
Sci Rep
, vol.4
, pp. 7461
-
-
Zhou, X.1
Ren, Y.2
Liu, A.3
Jin, R.4
Jiang, Q.5
Huang, Y.6
Kong, L.7
Wang, X.8
Zhang, L.9
-
13
-
-
33748992592
-
Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer
-
Duan Z, Foster R, Bell DA, Mahoney J, Wolak K, Vaidya A, Hampel C, Lee H, Seiden MV. Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer. Clin Cancer Res. 2006; 12:5055-5063.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5055-5063
-
-
Duan, Z.1
Foster, R.2
Bell, D.A.3
Mahoney, J.4
Wolak, K.5
Vaidya, A.6
Hampel, C.7
Lee, H.8
Seiden, M.V.9
-
14
-
-
3142554015
-
Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and-independent mechanisms
-
Dai Y, Rahmani M, Pei XY, Dent P, Grant S. Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and-independent mechanisms. Blood. 2004; 104:509-518.
-
(2004)
Blood
, vol.104
, pp. 509-518
-
-
Dai, Y.1
Rahmani, M.2
Pei, X.Y.3
Dent, P.4
Grant, S.5
-
15
-
-
79955592737
-
Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells
-
Chiu HC, Chou DL, Huang CT, Lin WH, Lien TW, Yen KJ, Hsu JT. Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells. Biochem Pharmacol. 2011; 81:1263-1270.
-
(2011)
Biochem Pharmacol
, vol.81
, pp. 1263-1270
-
-
Chiu, H.C.1
Chou, D.L.2
Huang, C.T.3
Lin, W.H.4
Lien, T.W.5
Yen, K.J.6
Hsu, J.T.7
-
16
-
-
84905726946
-
Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells
-
Lee HJ, Zhuang G, Cao Y, Du P, Kim HJ, Settleman J. Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells. Cancer Cell. 2014; 26:207-221.
-
(2014)
Cancer Cell
, vol.26
, pp. 207-221
-
-
Lee, H.J.1
Zhuang, G.2
Cao, Y.3
Du, P.4
Kim, H.J.5
Settleman, J.6
-
17
-
-
84866254673
-
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy
-
Sen M, Thomas SM, Kim S, Yeh JI, Ferris RL, Johnson JT, Duvvuri U, Lee J, Sahu N, Joyce S, Freilino ML, Shi H, Li C, et al. First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy. Cancer Discov. 2012; 2:694-705.
-
(2012)
Cancer Discov
, vol.2
, pp. 694-705
-
-
Sen, M.1
Thomas, S.M.2
Kim, S.3
Yeh, J.I.4
Ferris, R.L.5
Johnson, J.T.6
Duvvuri, U.7
Lee, J.8
Sahu, N.9
Joyce, S.10
Freilino, M.L.11
Shi, H.12
Li, C.13
-
18
-
-
84892928970
-
Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer
-
Lui VW, Peyser ND, Ng PK, Hritz J, Zeng Y, Lu Y, Li H, Wang L, Gilbert BR, General IJ, Bahar I, Ju Z, Wang Z, et al. Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer. Proc Natl Acad Sci U S A. 2014; 111:1114-1119.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 1114-1119
-
-
Lui, V.W.1
Peyser, N.D.2
Ng, P.K.3
Hritz, J.4
Zeng, Y.5
Lu, Y.6
Li, H.7
Wang, L.8
Gilbert, B.R.9
General, I.J.10
Bahar, I.11
Ju, Z.12
Wang, Z.13
-
19
-
-
33847246805
-
Oncomine 3.0: genes, pathways, and networks in a collection of 18, 000 cancer gene expression profiles
-
Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Varambally R, Yu J, Briggs BB, Barrette TR, Anstet MJ, Kincead-Beal C, Kulkarni P, Varambally S, Ghosh D, Chinnaiyan AM. Oncomine 3.0: genes, pathways, and networks in a collection of 18, 000 cancer gene expression profiles. Neoplasia. 2007; 9:166-180.
-
(2007)
Neoplasia
, vol.9
, pp. 166-180
-
-
Rhodes, D.R.1
Kalyana-Sundaram, S.2
Mahavisno, V.3
Varambally, R.4
Yu, J.5
Briggs, B.B.6
Barrette, T.R.7
Anstet, M.J.8
Kincead-Beal, C.9
Kulkarni, P.10
Varambally, S.11
Ghosh, D.12
Chinnaiyan, A.M.13
-
20
-
-
84923197605
-
Comprehensive genomic characterization of head and neck squamous cell carcinomas
-
Cancer Genome Atlas N. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature. 2015; 517:576-582.
-
(2015)
Nature
, vol.517
, pp. 576-582
-
-
-
21
-
-
84866918126
-
Chemopreventive and chemotherapeutic actions of mTOR inhibitor in genetically defined head and neck squamous cell carcinoma mouse model
-
Sun ZJ, Zhang L, Hall B, Bian Y, Gutkind JS, Kulkarni AB. Chemopreventive and chemotherapeutic actions of mTOR inhibitor in genetically defined head and neck squamous cell carcinoma mouse model. Clin Cancer Res. 2012; 18:5304-5313.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5304-5313
-
-
Sun, Z.J.1
Zhang, L.2
Hall, B.3
Bian, Y.4
Gutkind, J.S.5
Kulkarni, A.B.6
-
22
-
-
52549087785
-
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nature Reviews Cancer. 2008; 8:755-768.
-
(2008)
Nature Reviews Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
23
-
-
79952370202
-
The cancer stem cell: premises, promises and challenges
-
Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med. 2011; 17:313-319.
-
(2011)
Nat Med
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
24
-
-
42549112141
-
Cancer stem cell and cancer stemloids: From biology to therapy
-
Blagosklonny MV. Cancer stem cell and cancer stemloids: From biology to therapy. Cancer Biology & Therapy. 2014; 6:1684-1690.
-
(2014)
Cancer Biology & Therapy
, vol.6
, pp. 1684-1690
-
-
Blagosklonny, M.V.1
-
25
-
-
84865015481
-
Antitumor efficacy of sequential treatment with docetaxel and 5-fluorouracil against human oral cancer cells
-
Tamatani T, Ferdous T, Takamaru N, Hara K, Kinouchi M, Kuribayashi N, Ohe G, Uchida D, Nagai H, Fujisawa K, Miyamoto Y. Antitumor efficacy of sequential treatment with docetaxel and 5-fluorouracil against human oral cancer cells. Int J Oncol. 2012; 41:1148-1156.
-
(2012)
Int J Oncol
, vol.41
, pp. 1148-1156
-
-
Tamatani, T.1
Ferdous, T.2
Takamaru, N.3
Hara, K.4
Kinouchi, M.5
Kuribayashi, N.6
Ohe, G.7
Uchida, D.8
Nagai, H.9
Fujisawa, K.10
Miyamoto, Y.11
-
26
-
-
84875715657
-
Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma
-
Zhong LP, Zhang CP, Ren GX, Guo W, William WN Jr., Sun J, Zhu HG, Tu WY, Li J, Cai YL, Wang LZ, Fan XD, Wang ZH, et al. Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma. J Clin Oncol. 2013; 31:744-751.
-
(2013)
J Clin Oncol
, vol.31
, pp. 744-751
-
-
Zhong, L.P.1
Zhang, C.P.2
Ren, G.X.3
Guo, W.4
William, W.N.5
Sun, J.6
Zhu, H.G.7
Tu, W.Y.8
Li, J.9
Cai, Y.L.10
Wang, L.Z.11
Fan, X.D.12
Wang, Z.H.13
-
27
-
-
42549112141
-
Cancer stem cell and cancer stemloids: from biology to therapy
-
Blagosklonny MV. Cancer stem cell and cancer stemloids: from biology to therapy. Cancer Biol Ther. 2007; 6:1684-1690.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 1684-1690
-
-
Blagosklonny, M.V.1
-
28
-
-
84929133297
-
Review of STAT3 (Signal Transducers and Activators of Transcription) in head and neck cancer
-
Mali SB. Review of STAT3 (Signal Transducers and Activators of Transcription) in head and neck cancer. Oral Oncol. 2015; 51:565-569.
-
(2015)
Oral Oncol
, vol.51
, pp. 565-569
-
-
Mali, S.B.1
-
29
-
-
84867188698
-
Pro-malignant properties of STAT3 during chronic inflammation
-
Demaria M, Poli V. Pro-malignant properties of STAT3 during chronic inflammation. Oncotarget. 2012; 3:359-360.
-
(2012)
Oncotarget
, vol.3
, pp. 359-360
-
-
Demaria, M.1
Poli, V.2
-
30
-
-
84879679677
-
Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma
-
Ashizawa T, Miyata H, Iizuka A, Komiyama M, Oshita C, Kume A, Nogami M, Yagoto M, Ito I, Oishi T, Watanabe R, Mitsuya K, Matsuno K, et al. Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma. Int J Oncol. 2013; 43:219-227.
-
(2013)
Int J Oncol
, vol.43
, pp. 219-227
-
-
Ashizawa, T.1
Miyata, H.2
Iizuka, A.3
Komiyama, M.4
Oshita, C.5
Kume, A.6
Nogami, M.7
Yagoto, M.8
Ito, I.9
Oishi, T.10
Watanabe, R.11
Mitsuya, K.12
Matsuno, K.13
-
31
-
-
84897885694
-
Systemic administration of a cyclic signal transducer and activator of transcription 3 (STAT3) decoy oligonucleotide inhibits tumor growth without inducing toxicological effects
-
Sen M, Paul K, Freilino ML, Li H, Li C, Johnson DE, Wang L, Eiseman J, Grandis JR. Systemic administration of a cyclic signal transducer and activator of transcription 3 (STAT3) decoy oligonucleotide inhibits tumor growth without inducing toxicological effects. Mol Med. 2014; 20:46-56.
-
(2014)
Mol Med
, vol.20
, pp. 46-56
-
-
Sen, M.1
Paul, K.2
Freilino, M.L.3
Li, H.4
Li, C.5
Johnson, D.E.6
Wang, L.7
Eiseman, J.8
Grandis, J.R.9
-
32
-
-
84929353226
-
Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer
-
Thakur R, Trivedi R, Rastogi N, Singh M, Mishra DP. Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer. Sci Rep. 2015; 5:10194.
-
(2015)
Sci Rep
, vol.5
, pp. 10194
-
-
Thakur, R.1
Trivedi, R.2
Rastogi, N.3
Singh, M.4
Mishra, D.P.5
-
33
-
-
36048963331
-
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance
-
Zhou J, Wulfkuhle J, Zhang H, Gu P, Yang Y, Deng J, Margolick JB, Liotta LA, Petricoin E 3rd, Zhang Y. Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. Proc Natl Acad Sci U S A. 2007; 104:16158-16163.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 16158-16163
-
-
Zhou, J.1
Wulfkuhle, J.2
Zhang, H.3
Gu, P.4
Yang, Y.5
Deng, J.6
Margolick, J.B.7
Liotta, L.A.8
Petricoin, E.9
Zhang, Y.10
-
34
-
-
84929579442
-
Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells
-
Lee HT, Xue J, Chou PC, Zhou A, Yang P, Conrad CA, Aldape KD, Priebe W, Patterson C, Sawaya R, Xie K, Huang S. Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells. Oncotarget. 2015; 6:10016-10029.
-
(2015)
Oncotarget
, vol.6
, pp. 10016-10029
-
-
Lee, H.T.1
Xue, J.2
Chou, P.C.3
Zhou, A.4
Yang, P.5
Conrad, C.A.6
Aldape, K.D.7
Priebe, W.8
Patterson, C.9
Sawaya, R.10
Xie, K.11
Huang, S.12
-
35
-
-
84922627586
-
Identification of molecular signature of head and neck cancer stem-like cells
-
Shrivastava S, Steele R, Sowadski M, Crawford SE, Varvares M, Ray RB. Identification of molecular signature of head and neck cancer stem-like cells. Sci Rep. 2015; 5:7819.
-
(2015)
Sci Rep
, vol.5
, pp. 7819
-
-
Shrivastava, S.1
Steele, R.2
Sowadski, M.3
Crawford, S.E.4
Varvares, M.5
Ray, R.B.6
-
36
-
-
84931050133
-
Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and treatment
-
Ward R, Sims AH, Lee A, Lo C, Wynne L, Yusuf H, Gregson H, Lisanti MP, Sotgia F, Landberg G, Lamb R. Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and treatment. Oncotarget. 2015; 6:14687-14699.
-
(2015)
Oncotarget
, vol.6
, pp. 14687-14699
-
-
Ward, R.1
Sims, A.H.2
Lee, A.3
Lo, C.4
Wynne, L.5
Yusuf, H.6
Gregson, H.7
Lisanti, M.P.8
Sotgia, F.9
Landberg, G.10
Lamb, R.11
-
37
-
-
79960900961
-
Cell Fusion, Drug Resistance and Recurrence CSCs
-
Nagler C, Zanker KS, Dittmar T. Cell Fusion, Drug Resistance and Recurrence CSCs. Adv Exp Med Biol. 2011; 714:173-182.
-
(2011)
Adv Exp Med Biol
, vol.714
, pp. 173-182
-
-
Nagler, C.1
Zanker, K.S.2
Dittmar, T.3
-
38
-
-
44049100934
-
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
-
Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst. 2008; 100:672-679.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 672-679
-
-
Li, X.1
Lewis, M.T.2
Huang, J.3
Gutierrez, C.4
Osborne, C.K.5
Wu, M.F.6
Hilsenbeck, S.G.7
Pavlick, A.8
Zhang, X.9
Chamness, G.C.10
Wong, H.11
Rosen, J.12
Chang, J.C.13
-
39
-
-
84900456376
-
Cisplatin induces Bmi-1 and enhances the stem cell fraction in head and neck cancer
-
Nor C, Zhang Z, Warner KA, Bernardi L, Visioli F, Helman JI, Roesler R, Nor JE. Cisplatin induces Bmi-1 and enhances the stem cell fraction in head and neck cancer. Neoplasia. 2014; 16:137-146.
-
(2014)
Neoplasia
, vol.16
, pp. 137-146
-
-
Nor, C.1
Zhang, Z.2
Warner, K.A.3
Bernardi, L.4
Visioli, F.5
Helman, J.I.6
Roesler, R.7
Nor, J.E.8
-
40
-
-
84922742052
-
Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells
-
Liu WH, Chen MT, Wang ML, Lee YY, Chiou GY, Chien CS, Huang PI, Chen YW, Huang MC, Chiou SH, Shih YH, Ma HI. Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells. Oncotarget. 2015; 6:1750-1768.
-
(2015)
Oncotarget
, vol.6
, pp. 1750-1768
-
-
Liu, W.H.1
Chen, M.T.2
Wang, M.L.3
Lee, Y.Y.4
Chiou, G.Y.5
Chien, C.S.6
Huang, P.I.7
Chen, Y.W.8
Huang, M.C.9
Chiou, S.H.10
Shih, Y.H.11
Ma, H.I.12
-
41
-
-
84905084477
-
Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2
-
Wang DS, Patel A, Shukla S, Zhang YK, Wang YJ, Kathawala RJ, Robey RW, Zhang L, Yang DH, Talele TT, Bates SE, Ambudkar SV, Xu RH, et al. Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2. Oncotarget. 2014.
-
(2014)
Oncotarget
-
-
Wang, D.S.1
Patel, A.2
Shukla, S.3
Zhang, Y.K.4
Wang, Y.J.5
Kathawala, R.J.6
Robey, R.W.7
Zhang, L.8
Yang, D.H.9
Talele, T.T.10
Bates, S.E.11
Ambudkar, S.V.12
Xu, R.H.13
-
42
-
-
77952885076
-
Molecular characterisation of side population cells with cancer stem cell-like characteristics in smallcell lung cancer
-
Salcido CD, Larochelle A, Taylor BJ, Dunbar CE, Varticovski L. Molecular characterisation of side population cells with cancer stem cell-like characteristics in smallcell lung cancer. Br J Cancer. 2010; 102:1636-1644.
-
(2010)
Br J Cancer
, vol.102
, pp. 1636-1644
-
-
Salcido, C.D.1
Larochelle, A.2
Taylor, B.J.3
Dunbar, C.E.4
Varticovski, L.5
-
43
-
-
84924955932
-
Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop
-
Yang Z, Guo L, Liu D, Sun L, Chen H, Deng Q, Liu Y, Yu M, Ma Y, Guo N, Shi M. Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop. Oncotarget. 2015; 6:5072-5087.
-
(2015)
Oncotarget
, vol.6
, pp. 5072-5087
-
-
Yang, Z.1
Guo, L.2
Liu, D.3
Sun, L.4
Chen, H.5
Deng, Q.6
Liu, Y.7
Yu, M.8
Ma, Y.9
Guo, N.10
Shi, M.11
-
44
-
-
84907966000
-
Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancer
-
Han Z, Wang X, Ma L, Chen L, Xiao M, Huang L, Cao Y, Bai J, Ma D, Zhou J, Hong Z. Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancer. Oncotarget. 2014; 5:8416-8428.
-
(2014)
Oncotarget
, vol.5
, pp. 8416-8428
-
-
Han, Z.1
Wang, X.2
Ma, L.3
Chen, L.4
Xiao, M.5
Huang, L.6
Cao, Y.7
Bai, J.8
Ma, D.9
Zhou, J.10
Hong, Z.11
-
45
-
-
79953208248
-
STAT3 signaling: anticancer strategies and challenges
-
Johnston PA, Grandis JR. STAT3 signaling: anticancer strategies and challenges. Mol Interv. 2011; 11:18-26.
-
(2011)
Mol Interv
, vol.11
, pp. 18-26
-
-
Johnston, P.A.1
Grandis, J.R.2
-
46
-
-
70949094349
-
The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors
-
Hedvat M, Huszar D, Herrmann A, Gozgit JM, Schroeder A, Sheehy A, Buettner R, Proia D, Kowolik CM, Xin H, Armstrong B, Bebernitz G, Weng S, et al. The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors. Cancer Cell. 2009; 16:487-497.
-
(2009)
Cancer Cell
, vol.16
, pp. 487-497
-
-
Hedvat, M.1
Huszar, D.2
Herrmann, A.3
Gozgit, J.M.4
Schroeder, A.5
Sheehy, A.6
Buettner, R.7
Proia, D.8
Kowolik, C.M.9
Xin, H.10
Armstrong, B.11
Bebernitz, G.12
Weng, S.13
-
47
-
-
13944250650
-
In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach: implications for cancer therapy
-
Xi S, Gooding WE, Grandis JR. In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach: implications for cancer therapy. Oncogene. 2005; 24:970-979.
-
(2005)
Oncogene
, vol.24
, pp. 970-979
-
-
Xi, S.1
Gooding, W.E.2
Grandis, J.R.3
-
48
-
-
84931050133
-
Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and treatment
-
Ward R, Sims AH, Lee A, Lo C, Wynne L, Yusuf H, Gregson H, Lisanti MP, Sotgia F, Landberg G, Lamb R. Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and treatment. Oncotarget. 2015; 6:14687-14699.
-
(2015)
Oncotarget
, vol.6
, pp. 14687-14699
-
-
Ward, R.1
Sims, A.H.2
Lee, A.3
Lo, C.4
Wynne, L.5
Yusuf, H.6
Gregson, H.7
Lisanti, M.P.8
Sotgia, F.9
Landberg, G.10
Lamb, R.11
-
49
-
-
33747840618
-
Polymer conjugates as anticancer nanomedicines
-
Duncan R. Polymer conjugates as anticancer nanomedicines. Nat Rev Cancer. 2006; 6:688-701.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 688-701
-
-
Duncan, R.1
-
50
-
-
84875373097
-
MicroRNA-135b acts as a tumor promoter by targeting the hypoxia-inducible factor pathway in genetically defined mouse model of head and neck squamous cell carcinoma
-
Zhang L, Sun ZJ, Bian Y, Kulkarni AB. MicroRNA-135b acts as a tumor promoter by targeting the hypoxia-inducible factor pathway in genetically defined mouse model of head and neck squamous cell carcinoma. Cancer Lett. 2013; 331:230-238.
-
(2013)
Cancer Lett
, vol.331
, pp. 230-238
-
-
Zhang, L.1
Sun, Z.J.2
Bian, Y.3
Kulkarni, A.B.4
-
51
-
-
84928710938
-
Anterior gradient protein 2 expression in high grade head and neck squamous cell carcinoma correlated with cancer stem cell and epithelial mesenchymal transition
-
Ma SR, Wang WM, Huang CF, Zhang WF, Sun ZJ. Anterior gradient protein 2 expression in high grade head and neck squamous cell carcinoma correlated with cancer stem cell and epithelial mesenchymal transition. Oncotarget. 2015; 6:8807-8821.
-
(2015)
Oncotarget
, vol.6
, pp. 8807-8821
-
-
Ma, S.R.1
Wang, W.M.2
Huang, C.F.3
Zhang, W.F.4
Sun, Z.J.5
-
52
-
-
53249123425
-
Stem cell identification and sorting using the Hoechst 33342 side population (SP)
-
Chapter 9: Unit9 18
-
Goodell MA. Stem cell identification and sorting using the Hoechst 33342 side population (SP). Curr Protoc Cytom. 2005;. Chapter 9:Unit9 18.
-
(2005)
Curr Protoc Cytom
-
-
Goodell, M.A.1
-
53
-
-
84907086037
-
The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics
-
Boesch M, Zeimet AG, Reimer D, Schmidt S, Gastl G, Parson W, Spoeck F, Hatina J, Wolf D, Sopper S. The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics. Oncotarget. 2014; 5:7027-7039.
-
(2014)
Oncotarget
, vol.5
, pp. 7027-7039
-
-
Boesch, M.1
Zeimet, A.G.2
Reimer, D.3
Schmidt, S.4
Gastl, G.5
Parson, W.6
Spoeck, F.7
Hatina, J.8
Wolf, D.9
Sopper, S.10
-
54
-
-
84951746316
-
Inhibition of mTOR reduce Stat3 and PAI related angiogenesis in salivary gland adenoid cystic carcinoma
-
Yu GT, Bu LL, Zhao YY, Liu B, Zhang WF, Zhao YF, Zhang L, Sun ZJ. Inhibition of mTOR reduce Stat3 and PAI related angiogenesis in salivary gland adenoid cystic carcinoma. Am J Cancer Res. 2014; 4:764-775.
-
(2014)
Am J Cancer Res
, vol.4
, pp. 764-775
-
-
Yu, G.T.1
Bu, L.L.2
Zhao, Y.Y.3
Liu, B.4
Zhang, W.F.5
Zhao, Y.F.6
Zhang, L.7
Sun, Z.J.8
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