-
2
-
-
80052789088
-
Development of oral immunomodulatory agents in the management of multiple sclerosis
-
Nicholas R, Giannetti P, Alsanousi A, Friede T, Muraro PA. Development of oral immunomodulatory agents in the management of multiple sclerosis. Drug Des. Devel. Ther. 5, 255-274 (2011).
-
(2011)
Drug Des. Devel. Ther.
, vol.5
, pp. 255-274
-
-
Nicholas, R.1
Giannetti, P.2
Alsanousi, A.3
Friede, T.4
Muraro, P.A.5
-
3
-
-
84934756877
-
A systematic review of drugs in late-stage development for the treatment of multiple sclerosis: A focus on oral synthetic drugs
-
Safavi M, Nikfar S, Abdollahi M. A systematic review of drugs in late-stage development for the treatment of multiple sclerosis: a focus on oral synthetic drugs. Inflamm. Allergy Drug Targets 13(6), 351-366 (2015).
-
(2015)
Inflamm. Allergy Drug Targets
, vol.13
, Issue.6
, pp. 351-366
-
-
Safavi, M.1
Nikfar, S.2
Abdollahi, M.3
-
4
-
-
83255176681
-
The retinoid X receptors and their ligands
-
Dawson MI, Xia Z. The retinoid X receptors and their ligands. Biochim. Biophys. Acta 1821(1), 21-56 (2012).
-
(2012)
Biochim. Biophys. Acta
, vol.1821
, Issue.1
, pp. 21-56
-
-
Dawson, M.I.1
Xia, Z.2
-
5
-
-
84867928062
-
Advances in drug design with RXR modulators
-
Vaz B, de Lera ÁR. Advances in drug design with RXR modulators. Expert Opin. Drug Discov. 7(11), 1003-1016 (2012).
-
(2012)
Expert Opin. Drug Discov.
, vol.7
, Issue.11
, pp. 1003-1016
-
-
Vaz, B.1
De Lera, Á.R.2
-
6
-
-
0029832219
-
RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta-/-/RXR gamma-/-mutant mice are viable
-
Krezel W, Dupé V, Mark M, Dierich A, Kastner P, Chambon P. RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta-/-/RXR gamma-/-mutant mice are viable. Proc. Natl Acad. Sci. USA 93(17), 9010-9014 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, Issue.17
, pp. 9010-9014
-
-
Krezel, W.1
Dupé, V.2
Mark, M.3
Dierich, A.4
Kastner, P.5
Chambon, P.6
-
7
-
-
77953951450
-
Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice
-
Krzyzosiak A, Szyszka-Niagolov M, Wietrzych M, Gobaille S, Muramatsu S, Krezel W. Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice. Neuron 66(6), 908-920 (2010).
-
(2010)
Neuron
, vol.66
, Issue.6
, pp. 908-920
-
-
Krzyzosiak, A.1
Szyszka-Niagolov, M.2
Wietrzych, M.3
Gobaille, S.4
Muramatsu, S.5
Krezel, W.6
-
8
-
-
78650632445
-
Retinoid X receptor gamma signaling accelerates CNS remyelination
-
Huang JK, Jarjour AA, Nait Oumesmar B et al. Retinoid X receptor gamma signaling accelerates CNS remyelination. Nat. Neurosci. 14(1), 45-53 (2011).
-
(2011)
Nat. Neurosci.
, vol.14
, Issue.1
, pp. 45-53
-
-
Huang, J.K.1
Jarjour, A.A.2
Nait Oumesmar, B.3
-
9
-
-
0033593627
-
Stimulation of the myelin basic protein gene expression by 9-cis-retinoic acid and thyroid hormone: Activation in the context of its native promoter
-
Pombo PM, Barettino D, Ibarrola N, Vega S, Rodríguez-Peña A. Stimulation of the myelin basic protein gene expression by 9-cis-retinoic acid and thyroid hormone: activation in the context of its native promoter. Brain Res. Mol. Brain Res. 64(1), 92-100 (1999).
-
(1999)
Brain Res. Mol. Brain Res.
, vol.64
, Issue.1
, pp. 92-100
-
-
Pombo, P.M.1
Barettino, D.2
Ibarrola, N.3
Vega, S.4
Rodríguez-Peña, A.5
-
10
-
-
29244469634
-
9-cis-retinoic acid suppresses inflammatory responses of microglia and astrocytes
-
Xu J, Drew PD. 9-cis-retinoic acid suppresses inflammatory responses of microglia and astrocytes. J. Neuroimmunol. 171(1-2), 135-144 (2006).
-
(2006)
J. Neuroimmunol.
, vol.171
, Issue.1-2
, pp. 135-144
-
-
Xu, J.1
Drew, P.D.2
-
11
-
-
25444528680
-
Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia
-
Xu J, Storer PD, Chavis JA, Racke MK, Drew PD. Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia. J. Neurosci. Res. 81(3), 403-411 (2005).
-
(2005)
J. Neurosci. Res.
, vol.81
, Issue.3
, pp. 403-411
-
-
Xu, J.1
Storer, P.D.2
Chavis, J.A.3
Racke, M.K.4
Drew, P.D.5
-
12
-
-
33846821853
-
Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes
-
Zhang-Gandhi CX, Drew PD. Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes. J. Neuroimmunol. 183(1-2), 50-59 (2007).
-
(2007)
J. Neuroimmunol.
, vol.183
, Issue.1-2
, pp. 50-59
-
-
Zhang-Gandhi, C.X.1
Drew, P.D.2
-
13
-
-
84896462023
-
Retinoid X receptor ligands: A patent review (2007-2013)
-
Yamada S, Kakuta H. Retinoid X receptor ligands: a patent review (2007-2013). Expert Opin. Ther. Pat. 24(4), 443-452 (2014).
-
(2014)
Expert Opin. Ther. Pat.
, vol.24
, Issue.4
, pp. 443-452
-
-
Yamada, S.1
Kakuta, H.2
-
14
-
-
84877091761
-
Molecular pathways: Current role and future directions of the retinoic acid pathway in cancer prevention and treatment
-
Connolly RM, Nguyen NK, Sukumar S. Molecular pathways: current role and future directions of the retinoic acid pathway in cancer prevention and treatment. Clin. Cancer Res. 19(7), 1651-1659 (2013).
-
(2013)
Clin. Cancer Res.
, vol.19
, Issue.7
, pp. 1651-1659
-
-
Connolly, R.M.1
Nguyen, N.K.2
Sukumar, S.3
-
15
-
-
84922292271
-
Activation of the retinoid X receptor modulates angiotensin II-induced smooth muscle gene expression and inflammation in vascular smooth muscle cells
-
Lehman AMB, Montford JR, Horita H et al. Activation of the retinoid X receptor modulates angiotensin II-induced smooth muscle gene expression and inflammation in vascular smooth muscle cells. Mol. Pharmacol. 86(5), 570-579 (2014).
-
(2014)
Mol. Pharmacol.
, vol.86
, Issue.5
, pp. 570-579
-
-
Lehman, A.M.B.1
Montford, J.R.2
Horita, H.3
-
16
-
-
84922509175
-
The emerging role of bexarotene in the treatment of Alzheimer's disease: Current evidence
-
Tousi B. The emerging role of bexarotene in the treatment of Alzheimer's disease: current evidence. Neuropsychiatr. Dis. Treat. 11, 311-315 (2015).
-
(2015)
Neuropsychiatr. Dis. Treat.
, vol.11
, pp. 311-315
-
-
Tousi, B.1
-
17
-
-
84925854124
-
CNS drug design: Balancing physicochemical properties for optimal brain exposure
-
Rankovic Z. CNS drug design: balancing physicochemical properties for optimal brain exposure. J. Med. Chem. 58(6), 2584-2608 (2015).
-
(2015)
J. Med. Chem.
, vol.58
, Issue.6
, pp. 2584-2608
-
-
Rankovic, Z.1
|