메뉴 건너뛰기




Volumn 25, Issue 1, 2016, Pages 59-66

Angiotensin converting enzyme 2 and the kidney

Author keywords

Angiotensin converting enzyme 2; angiotensin II; kidney; renin angiotensin system

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; DIPEPTIDYL CARBOXYPEPTIDASE;

EID: 84951570082     PISSN: 10624821     EISSN: 14736543     Source Type: Journal    
DOI: 10.1097/MNH.0000000000000182     Document Type: Review
Times cited : (26)

References (52)
  • 1
    • 0028952503 scopus 로고
    • Regulation of blood pressure by the type IA receptor for angiotensin II
    • Ito M, Oliverio M, Mannon P, et al. Regulation of blood pressure by the type IA receptor for angiotensin II. Proc Natl Acad Sci USA 1995; 92:3521-3525.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3521-3525
    • Ito, M.1    Oliverio, M.2    Mannon, P.3
  • 2
    • 52449093411 scopus 로고    scopus 로고
    • Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension
    • Crowley SD, Frey CW, Gould SK, et al. Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension. Am J Physiol Renal Physiol 2008; 295:F515-F524.
    • (2008) Am J Physiol Renal Physiol , vol.295 , pp. F515-F524
    • Crowley, S.D.1    Frey, C.W.2    Gould, S.K.3
  • 3
    • 56549117604 scopus 로고    scopus 로고
    • Role of angiotensin II AT1 receptor activation in cardiovascular diseases
    • Billet S, Aguilar F, Baudry C, Clauser E. Role of angiotensin II AT1 receptor activation in cardiovascular diseases. Kidney Int 2008; 74:1379-1384.
    • (2008) Kidney Int , vol.74 , pp. 1379-1384
    • Billet, S.1    Aguilar, F.2    Baudry, C.3    Clauser, E.4
  • 4
    • 34548496478 scopus 로고    scopus 로고
    • Angiotensin II-induced reactive oxygen species and the kidney
    • Sachse A, Wolf G. Angiotensin II-induced reactive oxygen species and the kidney. J Am Soc Nephrol 2007; 18:2439-2446.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2439-2446
    • Sachse, A.1    Wolf, G.2
  • 5
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner B, Cooper M, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345:861-869.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.1    Cooper, M.2    De Zeeuw, D.3
  • 6
    • 0037160968 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
    • Dahlof B, Devereux R, Kjeldsen S, et al. Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002; 359:995-1003.
    • (2002) Lancet , vol.359 , pp. 995-1003
    • Dahlof, B.1    Devereux, R.2    Kjeldsen, S.3
  • 7
    • 0027517659 scopus 로고
    • The effect of angiotensin-convertingenzyme inhibition on diabetic nephropathy. The Collaborative Study Group
    • Lewis E, Hunsicker L, Bain R, Rohde R. The effect of angiotensin-convertingenzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N Engl J Med 1993; 329:1456-1462.
    • (1993) N Engl J Med , vol.329 , pp. 1456-1462
    • Lewis, E.1    Hunsicker, L.2    Bain, R.3    Rohde, R.4
  • 8
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis E, Hunsicker L, Clarke W, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345:851-860.
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.1    Hunsicker, L.2    Clarke, W.3
  • 9
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342:145-153.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3
  • 10
    • 0038053724 scopus 로고    scopus 로고
    • A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin i to angiotensin 1-9
    • Donoghue M, Hsieh F, Baronas E, et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000; 87:E1-E9.
    • (2000) Circ Res , vol.87 , pp. E1-E9
    • Donoghue, M.1    Hsieh, F.2    Baronas, E.3
  • 11
    • 18544378161 scopus 로고    scopus 로고
    • Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
    • Vickers C, Hales P, Kaushik V, et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 2002; 277:14838-14843.
    • (2002) J Biol Chem , vol.277 , pp. 14838-14843
    • Vickers, C.1    Hales, P.2    Kaushik, V.3
  • 12
    • 0034721906 scopus 로고    scopus 로고
    • A human homolog of angiotensinconverting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
    • Tipnis S, Hooper N, Hyde R, et al. A human homolog of angiotensinconverting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 2000; 275:33238-33243.
    • (2000) J Biol Chem , vol.275 , pp. 33238-33243
    • Tipnis, S.1    Hooper, N.2    Hyde, R.3
  • 13
    • 33750722109 scopus 로고    scopus 로고
    • Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: Implications for albuminuria in diabetes
    • Ye M, Wysocki J, William J, et al. Glomerular localization and expression of angiotensin-converting enzyme 2 and angiotensin-converting enzyme: implications for albuminuria in diabetes. J Am Soc Nephrol 2006; 17:3067-3075.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3067-3075
    • Ye, M.1    Wysocki, J.2    William, J.3
  • 15
    • 33846183617 scopus 로고    scopus 로고
    • Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system
    • Doobay MF, Talman LS, Obr TD, et al. Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol 2007; 292:R373-R381.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292 , pp. R373-R381
    • Doobay, M.F.1    Talman, L.S.2    Obr, T.D.3
  • 16
    • 2642539225 scopus 로고    scopus 로고
    • Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis
    • Hamming I, Timens W, Bulthuis ML, et al. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol 2004; 203:631-637.
    • (2004) J Pathol , vol.203 , pp. 631-637
    • Hamming, I.1    Timens, W.2    Bulthuis, M.L.3
  • 17
    • 28144453548 scopus 로고    scopus 로고
    • Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2
    • Paizis G, Tikellis C, Cooper ME, et al. Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2. Gut 2005; 54:1790-1796.
    • (2005) Gut , vol.54 , pp. 1790-1796
    • Paizis, G.1    Tikellis, C.2    Cooper, M.E.3
  • 18
    • 24044444558 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severeacute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensinconverting enzyme-2 (ACE2)
    • Lambert DW, Yarski M, Warner FJ, et al. Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severeacute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensinconverting enzyme-2 (ACE2). J Biol Chem 2005; 280:30113-30119.
    • (2005) J Biol Chem , vol.280 , pp. 30113-30119
    • Lambert, D.W.1    Yarski, M.2    Warner, F.J.3
  • 19
    • 70449625416 scopus 로고    scopus 로고
    • Selective and specific regulation of ectodomain shedding of angiotensin-converting enzyme 2 by tumor necrosis factor alpha-converting enzyme
    • Iwata M, Silva Enciso JE, Greenberg BH. Selective and specific regulation of ectodomain shedding of angiotensin-converting enzyme 2 by tumor necrosis factor alpha-converting enzyme. Am J Physiol Cell Physiol 2009; 297:C1318-C1329.
    • (2009) Am J Physiol Cell Physiol , vol.297 , pp. C1318-C1329
    • Iwata, M.1    Silva Enciso, J.E.2    Greenberg, B.H.3
  • 20
    • 67650081069 scopus 로고    scopus 로고
    • Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia
    • Jia HP, Look DC, Tan P, et al. Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia. Am J Physiol Lung Cell Mol Physiol 2009; 297:L84-L96.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297 , pp. L84-L96
    • Jia, H.P.1    Look, D.C.2    Tan, P.3
  • 21
    • 27944467680 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells
    • Warner FJ, Lew RA, Smith AI, et al. Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells. J Biol Chem 2005; 280:39353-39362.
    • (2005) J Biol Chem , vol.280 , pp. 39353-39362
    • Warner, F.J.1    Lew, R.A.2    Smith, A.I.3
  • 23
    • 84898623111 scopus 로고    scopus 로고
    • Characterization of angiotensinconverting enzyme 2 ectodomain shedding from mouse proximal tubular cells
    • Xiao F, Zimpelmann J, Agaybi S, et al. Characterization of angiotensinconverting enzyme 2 ectodomain shedding from mouse proximal tubular cells. PLoS One 2014; 9:e85958.
    • (2014) PLoS One , vol.9 , pp. e85958
    • Xiao, F.1    Zimpelmann, J.2    Agaybi, S.3
  • 24
    • 84876981345 scopus 로고    scopus 로고
    • Rosiglitazone treatment of type 2 diabetic db/db mice attenuates urinary albumin and angiotensin converting enzyme 2 excretion
    • Chodavarapu H, Grobe N, Somineni HK, et al. Rosiglitazone treatment of type 2 diabetic db/db mice attenuates urinary albumin and angiotensin converting enzyme 2 excretion. PLoS One 2013; 8:e62833.
    • (2013) PLoS One , vol.8 , pp. e62833
    • Chodavarapu, H.1    Grobe, N.2    Somineni, H.K.3
  • 25
    • 80051684129 scopus 로고    scopus 로고
    • Urinary angiotensin-converting enzyme 2 in patients with CKD
    • Mizuiri S, Aoki T, Hemmi H, et al. Urinary angiotensin-converting enzyme 2 in patients with CKD. Nephrology (Carlton) 2011; 16:567-572.
    • (2011) Nephrology (Carlton) , vol.16 , pp. 567-572
    • Mizuiri, S.1    Aoki, T.2    Hemmi, H.3
  • 26
    • 84874538781 scopus 로고    scopus 로고
    • High urinary ACE2 concentrations are associated with severity of glucose intolerance and microalbuminuria
    • Park SE, Kim WJ, Park SW, et al. High urinary ACE2 concentrations are associated with severity of glucose intolerance and microalbuminuria. Eur J Endocrinol 2013; 168:203-210.
    • (2013) Eur J Endocrinol , vol.168 , pp. 203-210
    • Park, S.E.1    Kim, W.J.2    Park, S.W.3
  • 27
    • 0037341829 scopus 로고    scopus 로고
    • Characterization of a new selective antagonist for angiotensin-(1-7), D-pro7-angiotensin-(1-7)
    • Santos RA, Haibara AS, Campagnole-Santos MJ, et al. Characterization of a new selective antagonist for angiotensin-(1-7), D-pro7-angiotensin-(1-7). Hypertension 2003; 41 (3 Pt 2):737-743.
    • (2003) Hypertension , vol.41 , Issue.3 , pp. 737-743
    • Santos, R.A.1    Haibara, A.S.2    Campagnole-Santos, M.J.3
  • 28
    • 84871867177 scopus 로고    scopus 로고
    • High-salt diet increases glomerular ACE/ACE2 ratio leading to oxidative stress and kidney damage
    • Bernardi S, Toffoli B, Zennaro C, et al. High-salt diet increases glomerular ACE/ACE2 ratio leading to oxidative stress and kidney damage. Nephrol Dial Transplant 2012; 27:1793-1800.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 1793-1800
    • Bernardi, S.1    Toffoli, B.2    Zennaro, C.3
  • 29
    • 2342472108 scopus 로고    scopus 로고
    • Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: A renoprotective combination
    • Ye M, Wysocki J, Naaz P, et al. Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination Hypertension 2004; 43:1120-1125.
    • (2004) Hypertension , vol.43 , pp. 1120-1125
    • Ye, M.1    Wysocki, J.2    Naaz, P.3
  • 30
    • 34249774906 scopus 로고    scopus 로고
    • Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio
    • Wakahara S, Konoshita T, Mizuno S, et al. Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio. Endocrinology 2007; 148:2453-2457.
    • (2007) Endocrinology , vol.148 , pp. 2453-2457
    • Wakahara, S.1    Konoshita, T.2    Mizuno, S.3
  • 31
    • 79954459188 scopus 로고    scopus 로고
    • Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats
    • Prieto MC, Gonzalez-Villalobos RA, Botros FT, et al. Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats. Am J Physiol Renal Physiol 2011; 300:F749-F755.
    • (2011) Am J Physiol Renal Physiol , vol.300 , pp. F749-F755
    • Prieto, M.C.1    Gonzalez-Villalobos, R.A.2    Botros, F.T.3
  • 32
    • 84864751446 scopus 로고    scopus 로고
    • High Na intake increases renal angiotensin II levels and reduces expression of the ACE2-AT(2)R-MasR axis in obese Zucker rats
    • Samuel P, Ali Q, Sabuhi R, et al. High Na intake increases renal angiotensin II levels and reduces expression of the ACE2-AT(2)R-MasR axis in obese Zucker rats. Am J Physiol Renal Physiol 2012; 303:F412-F419.
    • (2012) Am J Physiol Renal Physiol , vol.303 , pp. F412-F419
    • Samuel, P.1    Ali, Q.2    Sabuhi, R.3
  • 33
    • 79951851839 scopus 로고    scopus 로고
    • Expression of ACE and ACE2 in patients with hypertensive nephrosclerosis
    • Wang G, Lai FM, Kwan BC, et al. Expression of ACE and ACE2 in patients with hypertensive nephrosclerosis. Kidney Blood Press Res 2011; 34:141-149.
    • (2011) Kidney Blood Press Res , vol.34 , pp. 141-149
    • Wang, G.1    Lai, F.M.2    Kwan, B.C.3
  • 34
    • 84857784989 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2: Enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy
    • Batlle D, Wysocki J, Soler MJ, Ranganath K. Angiotensin-converting enzyme 2: enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy. Kidney Int 2012; 81:520-528.
    • (2012) Kidney Int , vol.81 , pp. 520-528
    • Batlle, D.1    Wysocki, J.2    Soler, M.J.3    Ranganath, K.4
  • 35
    • 0037142101 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 is an essential regulator of heart function
    • Crackower M, Sarao R, Oudit G, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 2002; 417:822-828.
    • (2002) Nature , vol.417 , pp. 822-828
    • Crackower, M.1    Sarao, R.2    Oudit, G.3
  • 36
    • 33645834948 scopus 로고    scopus 로고
    • Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II
    • Yamamoto K, Ohishi M, Katsuya T, et al. Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II. Hypertension 2006; 47:718-726.
    • (2006) Hypertension , vol.47 , pp. 718-726
    • Yamamoto, K.1    Ohishi, M.2    Katsuya, T.3
  • 37
    • 33746724157 scopus 로고    scopus 로고
    • Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice
    • Gurley SB, Allred A, Le TH, et al. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. J Clin Invest 2006; 116:2218-2225.
    • (2006) J Clin Invest , vol.116 , pp. 2218-2225
    • Gurley, S.B.1    Allred, A.2    Le, T.H.3
  • 38
    • 84938583935 scopus 로고    scopus 로고
    • Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling
    • Jin HY, Chen L J, Zhang ZZ, et al. Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling. J Transl Med 2015; 13:255.
    • (2015) J Transl Med , vol.13 , pp. 255
    • Jin, H.Y.1    Chen, L.J.2    Zhang, Z.Z.3
  • 39
    • 34548295365 scopus 로고    scopus 로고
    • Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
    • Wong DW, Oudit GY, Reich H, et al. Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. Am J Pathol 2007; 171:438-451.
    • (2007) Am J Pathol , vol.171 , pp. 438-451
    • Wong, D.W.1    Oudit, G.Y.2    Reich, H.3
  • 40
    • 20144388724 scopus 로고    scopus 로고
    • Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
    • Crowley SD, Gurley SB, Oliverio MI, et al. Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system. J Clin Invest 2005; 115:1092-1099.
    • (2005) J Clin Invest , vol.115 , pp. 1092-1099
    • Crowley, S.D.1    Gurley, S.B.2    Oliverio, M.I.3
  • 41
    • 85009108008 scopus 로고    scopus 로고
    • ACE2 deficiency increases NADPH-mediated oxidative stress in the kidney
    • Wysocki J, Ortiz-Melo DI, Mattocks NK, et al. ACE2 deficiency increases NADPH-mediated oxidative stress in the kidney. Physiol Rep 2014; 2:e00264.
    • (2014) Physiol Rep , vol.2 , pp. e00264
    • Wysocki, J.1    Ortiz-Melo, D.I.2    Mattocks, N.K.3
  • 43
    • 84977674294 scopus 로고    scopus 로고
    • 8d.01: Effects of angiotensin-converting enzyme 2 on renal oxidative stress levels in apolipoprotein E-deficient mice
    • Zhong J, Chen LJ, Zhang ZZ, et al. 8d.01: effects of angiotensin-converting enzyme 2 on renal oxidative stress levels in apolipoprotein E-deficient mice. J Hypertens 2015; 33 (Suppl 1):e113.
    • (2015) J Hypertens , vol.33 , pp. e113
    • Zhong, J.1    Chen, L.J.2    Zhang, Z.Z.3
  • 44
    • 0037341501 scopus 로고    scopus 로고
    • Characterization of renal angiotensinconverting enzyme 2 in diabetic nephropathy
    • Tikellis C, Johnston CI, Forbes JM, et al. Characterization of renal angiotensinconverting enzyme 2 in diabetic nephropathy. Hypertension 2003; 41:392-397.
    • (2003) Hypertension , vol.41 , pp. 392-397
    • Tikellis, C.1    Johnston, C.I.2    Forbes, J.M.3
  • 45
    • 84868369462 scopus 로고    scopus 로고
    • Loss of TIMP3 selectively exacerbates diabetic nephropathy
    • Basu R, Lee J, Wang Z, et al. Loss of TIMP3 selectively exacerbates diabetic nephropathy. Am J Physiol Renal Physiol 2012; F1341-F1352.
    • (2012) Am J Physiol Renal Physiol , pp. F1341-F1352
    • Basu, R.1    Lee, J.2    Wang, Z.3
  • 46
    • 23844557144 scopus 로고    scopus 로고
    • Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: A new therapeutic approach
    • Lautrette A, Li S, Alili R, et al. Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach. Nat Med 2005; 11:867-874.
    • (2005) Nat Med , vol.11 , pp. 867-874
    • Lautrette, A.1    Li, S.2    Alili, R.3
  • 47
    • 84886089553 scopus 로고    scopus 로고
    • Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension
    • Xia H, Sriramula S, Chhabra KH, Lazartigues E. Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension. Circ Res 2013; 113:1087-1096.
    • (2013) Circ Res , vol.113 , pp. 1087-1096
    • Xia, H.1    Sriramula, S.2    Chhabra, K.H.3    Lazartigues, E.4
  • 49
    • 34548153521 scopus 로고    scopus 로고
    • ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice
    • Soler MJ, Wysocki J, Ye M, et al. ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice. Kidney Int 2007; 72:614-623.
    • (2007) Kidney Int , vol.72 , pp. 614-623
    • Soler, M.J.1    Wysocki, J.2    Ye, M.3
  • 50
    • 84863802059 scopus 로고    scopus 로고
    • Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice
    • Nadarajah R, Milagres R, Dilauro M, et al. Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice. Kidney international 2012; 82:292-303.
    • (2012) Kidney International , vol.82 , pp. 292-303
    • Nadarajah, R.1    Milagres, R.2    Dilauro, M.3
  • 51
    • 78651497653 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: A comparison with ACE inhibition
    • Liu CX, Hu Q, Wang Y, et al. Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: a comparison with ACE inhibition. Mol Med 2011; 17:59-69.
    • (2011) Mol Med , vol.17 , pp. 59-69
    • Liu, C.X.1    Hu, Q.2    Wang, Y.3
  • 52
    • 84899818343 scopus 로고    scopus 로고
    • Insulin treatment attenuates renal ADAM17 and ACE2 shedding in diabetic Akita mice
    • Salem ES, Grobe N, Elased KM. Insulin treatment attenuates renal ADAM17 and ACE2 shedding in diabetic Akita mice. Am J Physiol Renal Physiol 2014; 306:F629-F639.
    • (2014) Am J Physiol Renal Physiol , vol.306 , pp. F629-F639
    • Salem, E.S.1    Grobe, N.2    Elased, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.