Topical delivery of aqueous micellar resolvin E1 analog (RX-10045)

International Journal of Pharmaceutics

Volumn 498, Issue 1-2, 2016, Pages 326-334

  Cholkar, Kishore ^a,c   Gilger, Brian C ^b   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c RiconPharma LLC   (United States)

Author keywords

Aqueous; Back of the eye; Drug delivery; Eye drop; Formulation; Inflammation; Micelles; Posterior; Rabbits; Resolving; Retina choroid; Sclera; Topical

Indexed keywords

OCULAR ANTIINFLAMMATORY AGENT; PLACEBO; RX 10045; UNCLASSIFIED DRUG; 5S,12R,18R-TRIHYDROXY-6Z,8E,10E,14Z,16E-EICOSAPENTAENOIC ACID; ICOSAPENTAENOIC ACID; MICELLE; WATER;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ENCAPSULATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; DRUG TISSUE LEVEL; DRUG TOLERABILITY; EXPERIMENTAL RABBIT; EYE EXAMINATION; FEMALE; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INTRAOCULAR PRESSURE; LIMIT OF QUANTITATION; MICELLE; NONHUMAN; OCULAR TISSUE; PARTICLE SIZE; PRIORITY JOURNAL; SCORING SYSTEM; SURFACE CHARGE; SURFACE PROPERTY; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG EFFECTS; INTRAOCULAR DRUG ADMINISTRATION; METABOLISM; PHYSIOLOGY; PROCEDURES; RABBIT; SOLUBILITY; TISSUE DISTRIBUTION; TOPICAL DRUG ADMINISTRATION; VITREOUS BODY;

ADMINISTRATION, OPHTHALMIC; ADMINISTRATION, TOPICAL; ANIMALS; DRUG DELIVERY SYSTEMS; EICOSAPENTAENOIC ACID; FEMALE; MICELLES; RABBITS; SOLUBILITY; TISSUE DISTRIBUTION; VITREOUS BODY; WATER;

EID: 84951304322     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.12.037     Document Type: Article

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