Age intrinsic loss of telomere protection via TRF1 reduction in endothelial cells

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1863, Issue 2, 2016, Pages 360-367

  Hohensinner, P J ^a   Kaun, C ^a   Buchberger, E ^a   Ebenbauer, B ^a,b   Demyanets, S ^a   Huk, I ^a   Eppel, W ^c   Maurer, G ^a   Huber, K ^b,d   Wojta, J ^a,b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Ludwig Boltzmann Cluster for Cardiovascular Research   (Austria)

^c UNIV KLIN FÜR FRAUENHEILKUNDE   (Austria)

^d WILHELMINEN HOSPITAL   (Austria)

Author keywords

Aging; DNA damage; Senescence; Shelterin; Telomere dysfunction

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; TELOMERIC REPEAT BINDING FACTOR 1; UNCLASSIFIED DRUG; CCL2 PROTEIN, HUMAN; SERPINE1 PROTEIN, HUMAN;

ARTICLE; CELL AGING; CELL PROTECTION; CELL SIZE; CONTROLLED STUDY; DNA DAMAGE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCTION; REJUVENATION; TELOMERE; CELL CULTURE; CONFOCAL MICROSCOPY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL AGING; CELLS, CULTURED; CHEMOKINE CCL2; DNA DAMAGE; GENE EXPRESSION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICROSCOPY, CONFOCAL; PLASMINOGEN ACTIVATOR INHIBITOR 1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 1;

EID: 84951187204     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2015.11.034     Document Type: Article

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