Cellular senescence determines endothelial cell damage induced by uremia

Experimental Gerontology

Volumn 48, Issue 8, 2013, Pages 766-773

  Carracedo, Julia ^a,b   Buendía, Paula ^a,b   Merino, Ana ^a,b,c   Soriano, Sagrario ^a,b   Esquivias, Elvira ^a,b   Martín Malo, Alejandro ^a,b   Aljama, Pedro ^a,b   Ramírez, Rafael ^a,b,d  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^d UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Damage endothelial; Endothelial senescence; Mitochondria alterations; Oxidative stress; Uremia

Indexed keywords

ASCORBIC ACID; BETA GALACTOSIDASE; CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; APOPTOSIS; ARTICLE; CELL AGING; CELL DAMAGE; CELL STRESS; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM LESION; FEMALE; HUMAN; HUMAN CELL; MALE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SERUM; TELOMERE; UMBILICAL VEIN ENDOTHELIAL CELL; UREMIA; VASCULAR ENDOTHELIUM;

CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; CKD; CLCR; CREATININE CLEARANCE; CVD; DAMAGE ENDOTHELIAL; ENDOTHELIAL SENESCENCE; HE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUVEC; HYDROETHIDINE; INTEGRATED OPTICAL DENSITY; IOD; MDR-D; MITOCHONDRIA ALTERATIONS; MODIFICATION OF DIET IN RENAL DISEASE; OXIDATIVE STRESS; PBS; PDS; PHOSPHATE-BUFFERED SALINE; PI; POPULATION DOUBLINGS; PROPIDIUM IODIDE; RAT ENDOTHELIAL CELL ANTIGEN-1; REACTIVE OXYGEN SPECIES; RECA-I; RELATIVE TELOMERE LENGTH; ROS; RTL; SIPS; STRESS-INDUCED PREMATURE SENESCENCE; UREMIA; VIT C; VITAMIN C;

AGED; ANIMALS; APOPTOSIS; ASCORBIC ACID; CELL AGING; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, ANIMAL; NF-KAPPA B; OXIDATIVE STRESS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SERUM; UREMIA;

ANIMALIA; RATTUS;

EID: 84879261404     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2013.04.004     Document Type: Article

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