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Volumn 26, Issue 25, 2015, Pages 4607-4617

Inhibition of the mitochondrial fission protein dynamin-related protein 1 (Drp1) impairs mitochondrial fission and mitotic catastrophe after x-irradiation

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; DYNAMIN RELATED PROTEIN 1; MITOCHONDRIAL PROTEIN; UNCLASSIFIED DRUG; CYCLIN B1; DNM1L PROTEIN, MOUSE; DYNAMIN;

EID: 84951130958     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E15-03-0181     Document Type: Article
Times cited : (38)

References (61)
  • 2
    • 33846584645 scopus 로고    scopus 로고
    • Mitotic arrest and cell fate: Why and how mitotic inhibition of transcription drives mutually exclusive events
    • Blagosklonny MV (2007). Mitotic arrest and cell fate: why and how mitotic inhibition of transcription drives mutually exclusive events. Cell Cycle 6, 70-74.
    • (2007) Cell Cycle , vol.6 , pp. 70-74
    • Blagosklonny, M.V.1
  • 3
    • 75749117063 scopus 로고    scopus 로고
    • DNA damage induces Chk1-dependent threonine-160 phosphorylation and activation of Cdk2
    • Bourke E, Brown JAL, Takeda S, Hochegger H, Morrison CG (2010). DNA damage induces Chk1-dependent threonine-160 phosphorylation and activation of Cdk2. Oncogene 29, 616-624.
    • (2011) Oncogene , vol.29 , pp. 616-624
    • Bourke, E.1    Brown, J.A.L.2    Takeda, S.3    Hochegger, H.4    Morrison, C.G.5
  • 4
    • 0035188129 scopus 로고    scopus 로고
    • Managing the centrosome numbers game: From chaos to stability in cancer cell division
    • Brinkley BR (2001). Managing the centrosome numbers game: from chaos to stability in cancer cell division. Trends Cell Biol 11, 18-21.
    • (2001) Trends Cell Biol , vol.11 , pp. 18-21
    • Brinkley, B.R.1
  • 5
    • 33744996707 scopus 로고    scopus 로고
    • Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
    • Brito DA, Rieder CL (2006). Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint. Curr Biol 16, 1194-1200.
    • (2006) Curr Biol , vol.16 , pp. 1194-1200
    • Brito, D.A.1    Rieder, C.L.2
  • 6
    • 38849099158 scopus 로고    scopus 로고
    • Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bakdependent mitochondrial outer membrane permeabilization
    • Cassidy-Stone A, Chipuk JE, Ingerman E, Song C, Yoo C, Kuwana T, Kurth MJ, Shaw JT, Hinshaw JE, Green DR, et al. (2008). Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bakdependent mitochondrial outer membrane permeabilization. Dev Cell 14, 193-204.
    • (2008) Dev Cell , vol.14 , pp. 193-204
    • Cassidy-Stone, A.1    Chipuk, J.E.2    Ingerman, E.3    Song, C.4    Yoo, C.5    Kuwana, T.6    Kurth, M.J.7    Shaw, J.T.8    Hinshaw, J.E.9    Green, D.R.10
  • 9
    • 34247499892 scopus 로고    scopus 로고
    • Mitochondrial dynamics in the regulation of neuronal cell death
    • Cheung ECC, McBride HM, Slack RS (2007). Mitochondrial dynamics in the regulation of neuronal cell death. Apoptosis 12, 979-992.
    • (2007) Apoptosis , vol.12 , pp. 979-992
    • Cheung, E.C.C.1    McBride, H.M.2    Slack, R.S.3
  • 10
    • 0032473421 scopus 로고    scopus 로고
    • The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts
    • Descombes P, Nigg EA (1998). The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. EMBO J 17, 1328-1335.
    • (1998) EMBO J , vol.17 , pp. 1328-1335
    • Descombes, P.1    Nigg, E.A.2
  • 11
    • 35448960851 scopus 로고    scopus 로고
    • Functions and dysfunctions of mitochondrial dynamics
    • Detmer SA, Chan DC (2007). Functions and dysfunctions of mitochondrial dynamics. Nat Rev Mol Cell Biol 8, 870-879.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 870-879
    • Detmer, S.A.1    Chan, D.C.2
  • 12
    • 33847060042 scopus 로고    scopus 로고
    • Involvement of centrosome amplification in radiation-induced mitotic catastrophe
    • Dodson H, Wheatley SP, Morrison CG (2007). Involvement of centrosome amplification in radiation-induced mitotic catastrophe. Cell Cycle 6, 364-370.
    • (2007) Cell Cycle , vol.6 , pp. 364-370
    • Dodson, H.1    Wheatley, S.P.2    Morrison, C.G.3
  • 13
    • 38949099707 scopus 로고    scopus 로고
    • The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells
    • Engelbert D, Schnerch D, Baumgarten A, Wch R (2008). The ubiquitin ligase APC(Cdh1) is required to maintain genome integrity in primary human cells. Oncogene 27, 907-917.
    • (2008) Oncogene , vol.27 , pp. 907-917
    • Engelbert, D.1    Schnerch, D.2    Baumgarten, A.3    Wch, R.4
  • 14
    • 77954641944 scopus 로고    scopus 로고
    • Radiation-induced cell death mechanisms
    • Eriksson D, Stigbrand T (2010). Radiation-induced cell death mechanisms. Tumour Biol 31, 363-372.
    • (2011) Tumour Biol , vol.31 , pp. 363-372
    • Eriksson, D.1    Stigbrand, T.2
  • 16
    • 0031771414 scopus 로고    scopus 로고
    • Ionizing radiation stimulates mitochondrial gene expression and activity
    • Gong B, Chen Q, Almasan A (1998). Ionizing radiation stimulates mitochondrial gene expression and activity. Radiat Res 150, 505-512.
    • (1998) Radiat Res , vol.150 , pp. 505-512
    • Gong, B.1    Chen, Q.2    Almasan, A.3
  • 17
    • 34250204271 scopus 로고    scopus 로고
    • The machines that divide and fuse mitochondria
    • Hoppins S, Lackner L, Nunnari J (2007). The machines that divide and fuse mitochondria. Annu Rev Biochem 76, 751-780.
    • (2007) Annu Rev Biochem , vol.76 , pp. 751-780
    • Hoppins, S.1    Lackner, L.2    Nunnari, J.3
  • 19
    • 45549109219 scopus 로고    scopus 로고
    • Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint
    • Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen TJ, Muschel RJ (2008). Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint. Cancer Res 68, 3724-3732.
    • (2008) Cancer Res , vol.68 , pp. 3724-3732
    • Huang, H.1    Fletcher, L.2    Beeharry, N.3    Daniel, R.4    Kao, G.5    Yen, T.J.6    Muschel, R.J.7
  • 20
    • 0026571114 scopus 로고
    • The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo
    • Hunt T, Luca FC, Ruderman JV (1992). The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo. J Cell Biol 116, 707-724.
    • (1992) J Cell Biol , vol.116 , pp. 707-724
    • Hunt, T.1    Luca, F.C.2    Ruderman, J.V.3
  • 21
    • 0141757479 scopus 로고    scopus 로고
    • DNA damage checkpoint control in cells exposed to ionizing radiation
    • Iliakis G, Wang Y, Guan J, Wang H (2003). DNA damage checkpoint control in cells exposed to ionizing radiation. Oncogene 22, 5834-5847.
    • (2003) Oncogene , vol.22 , pp. 5834-5847
    • Iliakis, G.1    Wang, Y.2    Guan, J.3    Wang, H.4
  • 22
    • 78649674320 scopus 로고    scopus 로고
    • A centrosome-Autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage
    • Inan B, Dodson H, Morrison CG (2010). A centrosome-Autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage. Mol Biol Cell 21, 3866-3877.
    • (2011) Mol Biol Cell , vol.21 , pp. 3866-3877
    • Inan Dodson, B.H.1    Morrison, C.G.2
  • 24
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson SP, Bartek J (2009). The DNA-damage response in human biology and disease. Nature 461, 1071-1078.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 25
    • 13944278072 scopus 로고    scopus 로고
    • DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. Elegans
    • Jagasia R, Grote P, Westermann B, Conradt B (2005). DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans. Nature 433, 754-760.
    • (2005) Nature , vol.433 , pp. 754-760
    • Jagasia, R.1    Grote, P.2    Westermann, B.3    Conradt, B.4
  • 26
    • 0043166392 scopus 로고    scopus 로고
    • Dynamics of mitochondrial morphology in healthy cells and during apoptosis
    • Karbowski M, Youle RJ (2003). Dynamics of mitochondrial morphology in healthy cells and during apoptosis. Cell Death Differ 10, 870-880.
    • (2003) Cell Death Differ , vol.10 , pp. 870-880
    • Karbowski, M.1    Youle, R.J.2
  • 27
    • 80555148138 scopus 로고    scopus 로고
    • Ionizing radiation accelerates Drp1-dependent mitochondrial fission, which involves delayed mitochondrial reactive oxygen species production in normal human fibroblast-like cells
    • Kobashigawa S, Suzuki K, Yamashita S (2011). Ionizing radiation accelerates Drp1-dependent mitochondrial fission, which involves delayed mitochondrial reactive oxygen species production in normal human fibroblast-like cells. Biochem Biophys Res Commun 414, 795-800.
    • (2011) Biochem Biophys Res Commun , vol.414 , pp. 795-800
    • Kobashigawa, S.1    Suzuki, K.2    Yamashita, S.3
  • 28
    • 77951822932 scopus 로고    scopus 로고
    • Mitochondrial gene expression changes in normal and mitochondrial mutant cells after exposure to ionizing radiation
    • Kulkarni R, Marples B, Balasubramaniam M, Thomas RA, Tucker JD (2010). Mitochondrial gene expression changes in normal and mitochondrial mutant cells after exposure to ionizing radiation. Radiat Res 173, 635-644.
    • (2011) Radiat Res , vol.173 , pp. 635-644
    • Kulkarni, R.1    Marples, B.2    Balasubramaniam, M.3    Thomas, R.A.4    Tucker, J.D.5
  • 29
    • 0030462914 scopus 로고    scopus 로고
    • Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes
    • Lane HA, Nigg EA (1996). Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes. J Cell Biol 135, 1701-1713.
    • (1996) J Cell Biol , vol.135 , pp. 1701-1713
    • Lane, H.A.1    Nigg, E.A.2
  • 30
    • 84877273607 scopus 로고    scopus 로고
    • Dying cell clearance and its impact on the outcome of tumor radiotherapy
    • Lauber K, Ernst A, Orth M, Herrmann M, Belka C (2012). Dying cell clearance and its impact on the outcome of tumor radiotherapy. Front Oncol 2, 1-14.
    • (2012) Front Oncol , vol.2 , pp. 1-14
    • Lauber, K.1    Ernst, A.2    Orth, M.3    Herrmann, M.4    Belka, C.5
  • 32
    • 78650058233 scopus 로고    scopus 로고
    • Mitochondrial fission leads to Smac/DIABLO release quenched by ARC
    • Li J, Li Y, Qin D, Von Harsdorf R, Li P (2010). Mitochondrial fission leads to Smac/DIABLO release quenched by ARC. Apoptosis 15, 1187-1196.
    • (2011) Apoptosis , vol.15 , pp. 1187-1196
    • Li, J.1    Li, Y.2    Qin, D.3    Von Harsdorf, R.4    Li, P.5
  • 33
    • 84861640093 scopus 로고    scopus 로고
    • Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension
    • Marsboom G, Toth PT, Ryan JJ, Hong Z, Wu X, Fang YH, Thenappan T, Piao L, Zhang HJ, Pogoriler J, et al. (2012). Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ Res 110, 1484-1497.
    • (2012) Circ Res , vol.110 , pp. 1484-1497
    • Marsboom, G.1    Toth, P.T.2    Ryan, J.J.3    Hong, Z.4    Wu, X.5    Fang, Y.H.6    Thenappan, T.7    Piao, L.8    Zhang, H.J.9    Pogoriler, J.10
  • 34
    • 0033145516 scopus 로고    scopus 로고
    • Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
    • Meraldi P, Lukas J, Fry AM, Bartek J, Nigg EA (1999). Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat Cell Biol 1, 88-93.
    • (1999) Nat Cell Biol , vol.1 , pp. 88-93
    • Meraldi, P.1    Lukas, J.2    Fry, A.M.3    Bartek, J.4    Nigg, E.A.5
  • 36
    • 34548564427 scopus 로고    scopus 로고
    • Increased mitochondrial mass in cells with functionally compromised mitochondria after exposure to both direct gamma radiation and bystander factors
    • Nugent SME, Mothersill CE, Seymour C, Mcclean B, Fiona M, Murphy JEJ, Lyng M, Lyng FM (2007). Increased mitochondrial mass in cells with functionally compromised mitochondria after exposure to both direct gamma radiation and bystander factors. Radiat Res 168, 134-142.
    • (2007) Radiat Res , vol.168 , pp. 134-142
    • Nugent, S.M.E.1    Mothersill, C.E.2    Seymour, C.3    Mcclean, B.4    Fiona, M.5    Murphy, J.E.J.6    Lyng, M.7    Lyng, F.M.8
  • 37
    • 84858376953 scopus 로고    scopus 로고
    • Mitochondria: In sickness and in health
    • Nunnari J, Suomalainen A (2012). Mitochondria: in sickness and in health. Cell 148, 1145-1159.
    • (2012) Cell , vol.148 , pp. 1145-1159
    • Nunnari, J.1    Suomalainen, A.2
  • 39
    • 84875273810 scopus 로고    scopus 로고
    • New insights into the function and regulation of mitochondrial fission
    • Otera H, Ishihara N, Mihara K (2013). New insights into the function and regulation of mitochondrial fission. Biochim Biophys Acta 1833, 1256-1268.
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 1256-1268
    • Otera, H.1    Ishihara, N.2    Mihara, K.3
  • 40
    • 84891122759 scopus 로고    scopus 로고
    • Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer
    • Pihan GA (2013). Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer. Front Oncol 3, 277.
    • (2013) Front Oncol , vol.3 , pp. 277
    • Pihan, G.A.1
  • 41
    • 79959555511 scopus 로고    scopus 로고
    • Cubism and the cell cycle: The many faces of the APC/C
    • Pines J (2011). Cubism and the cell cycle: The many faces of the APC/C. Nat Rev Mol Cell Biol 12, 427-438.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 427-438
    • Pines, J.1
  • 42
    • 77949450557 scopus 로고    scopus 로고
    • Mechanisms of drug-induced mitotic catastrophe in cancer cells
    • Portugal J, Mansilla S, Bataller M (2010). Mechanisms of drug-induced mitotic catastrophe in cancer cells. Curr Pharm Des 16, 69-78.
    • (2011) Curr Pharm des , vol.16 , pp. 69-78
    • Portugal, J.1    Mansilla, S.2    Bataller, M.3
  • 43
    • 84868021612 scopus 로고    scopus 로고
    • Oscillation of APC/C activity during cell cycle arrest promotes centrosome amplification
    • Prosser SL, Samant MD, Baxter JE, Morrison CG, Fry AM (2012). Oscillation of APC/C activity during cell cycle arrest promotes centrosome amplification. J Cell Sci 125, 5353-5368.
    • (2012) J Cell Sci , vol.125 , pp. 5353-5368
    • Prosser, S.L.1    Samant, M.D.2    Baxter, J.E.3    Morrison, C.G.4    Fry, A.M.5
  • 44
    • 84874694989 scopus 로고    scopus 로고
    • Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress
    • Qian W, Choi S, Gibson GA, Watkins SC, Bakkenist CJ, Van Houten B (2012). Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress. J Cell Sci 125, 5745-5757.
    • (2012) J Cell Sci , vol.125 , pp. 5745-5757
    • Qian, W.1    Choi, S.2    Gibson, G.A.3    Watkins, S.C.4    Bakkenist, C.J.5    Van Houten, B.6
  • 45
    • 79952260492 scopus 로고    scopus 로고
    • The role of mitochondria in the radiation-induced bystander effect in human lymphoblastoid cells
    • Rajendran S, Harrison SH, Thomas RA, Tucker JD (2011). The role of mitochondria in the radiation-induced bystander effect in human lymphoblastoid cells. Radiat Res 175, 159-171.
    • (2011) Radiat Res , vol.175 , pp. 159-171
    • Rajendran, S.1    Harrison, S.H.2    Thomas, R.A.3    Tucker, J.D.4
  • 49
    • 84856120839 scopus 로고    scopus 로고
    • Monitoring APC/C activity in the presence of chromosomal misalignment in unperturbed cell populations
    • Schnerch D, Follo M, Krohs J, Felthaus J, Engelhardt M, Wch R (2012). Monitoring APC/C activity in the presence of chromosomal misalignment in unperturbed cell populations. Cell Cycle 11, 310-321.
    • (2012) Cell Cycle , vol.11 , pp. 310-321
    • Schnerch, D.1    Follo, M.2    Krohs, J.3    Felthaus, J.4    Engelhardt, M.5    Wch, R.6
  • 50
    • 84862796326 scopus 로고    scopus 로고
    • Live-cell imaging visualizes frequent mitotic skipping during senescence-like growth arrest in mammary carcinoma cells exposed to ionizing radiation
    • Suzuki M, Yamauchi M, Oka Y, Suzuki K, Yamashita S (2012). Live-cell imaging visualizes frequent mitotic skipping during senescence-like growth arrest in mammary carcinoma cells exposed to ionizing radiation. Int J Radiat Oncol Biol Phys 83, e241-e250.
    • (2012) Int J Radiat Oncol Biol Phys , vol.83 , pp. e241-e250
    • Suzuki, M.1    Yamauchi, M.2    Oka, Y.3    Suzuki, K.4    Yamashita, S.5
  • 51
    • 34249689057 scopus 로고    scopus 로고
    • Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
    • Taguchi N, Ishihara N, Jofuku A, Oka T, Mihara K (2007). Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. J Biol Chem 282, 11521-11529.
    • (2007) J Biol Chem , vol.282 , pp. 11521-11529
    • Taguchi, N.1    Ishihara, N.2    Jofuku, A.3    Oka, T.4    Mihara, K.5
  • 52
    • 0035843140 scopus 로고    scopus 로고
    • Irradiation of mitochondria initiates apoptosis in a cell free system
    • Taneja N, Tjalkens R, Philbert MA, Rehemtulla A (2001). Irradiation of mitochondria initiates apoptosis in a cell free system. Oncogene 20, 167-177.
    • (2001) Oncogene , vol.20 , pp. 167-177
    • Taneja, N.1    Tjalkens, R.2    Philbert, M.A.3    Rehemtulla, A.4
  • 55
    • 79960957085 scopus 로고    scopus 로고
    • Mitotic catastrophe: A mechanism for avoiding genomic instability
    • Vitale I, Galluzzi L, Castedo M, Kroemer G (2011). Mitotic catastrophe: A mechanism for avoiding genomic instability. Nat Rev Mol Cell Biol 12, 385-392.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 385-392
    • Vitale, I.1    Galluzzi, L.2    Castedo, M.3    Kroemer, G.4
  • 57
    • 84862284114 scopus 로고    scopus 로고
    • Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint
    • Yamamori T, Yasui H, Yamazumi M, Wada Y, Nakamura Y, Nakamura H, Inanami O (2012). Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint. Free Radic Biol Med 53, 260-270.
    • (2012) Free Radic Biol Med , vol.53 , pp. 260-270
    • Yamamori, T.1    Yasui, H.2    Yamazumi, M.3    Wada, Y.4    Nakamura, Y.5    Nakamura, H.6    Inanami, O.7
  • 58
    • 84865544952 scopus 로고    scopus 로고
    • Mitochondrial fission, fusion, and stress
    • Youle RJ, van der Bliek AM (2012). Mitochondrial fission, fusion, and stress. Science 337, 1062-1065.
    • (2012) Science , vol.337 , pp. 1062-1065
    • Youle, R.J.1    Van Der Bliek, A.M.2
  • 59
    • 84888378078 scopus 로고    scopus 로고
    • Cytoplasmic irradiation results in mitochondrial dysfunction and DRP1-dependent mitochondrial fission
    • Zhang B, Davidson MM, Zhou H, Wang C, Walker WF, Hei TK (2013). Cytoplasmic irradiation results in mitochondrial dysfunction and DRP1-dependent mitochondrial fission. Cancer Res 73, 6700-6710.
    • (2013) Cancer Res , vol.73 , pp. 6700-6710
    • Zhang, B.1    Davidson, M.M.2    Zhou, H.3    Wang, C.4    Walker, W.F.5    Hei, T.K.6
  • 60
    • 84900553387 scopus 로고    scopus 로고
    • Amelioration of ischemic mitochondrial injury and Bax-dependent outer membrane permeabilization by Mdivi-1
    • Zhao Y-X, Cui M, Chen S-F, Dong Q, Liu X-Y (2014). Amelioration of ischemic mitochondrial injury and Bax-dependent outer membrane permeabilization by Mdivi-1. CNS Neurosci Ther 20, 528-538.
    • (2014) CNS Neurosci Ther , vol.20 , pp. 528-538
    • Zhao, Y.-X.1    Cui, M.2    Chen, S.-F.3    Dong, Q.4    Liu, X.-Y.5
  • 61
    • 42049122330 scopus 로고    scopus 로고
    • Mitochondrial function and nuclear factor-kappaB-mediated signaling in radiationinduced bystander effects
    • Zhou H, Ivanov VN, Lien Y-C, Davidson M, Hei TK (2008). Mitochondrial function and nuclear factor-kappaB-mediated signaling in radiationinduced bystander effects. Cancer Res 68, 2233-2240.
    • (2008) Cancer Res , vol.68 , pp. 2233-2240
    • Zhou, H.1    Ivanov, V.N.2    Lien, Y.-C.3    Davidson, M.4    Hei, T.K.5


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