Distinct phenotypes of cigarette smokers identified by cluster analysis of patients with severe asthma

Annals of the American Thoracic Society

Volumn 12, Issue 12, 2015, Pages 1771-1780

  Konno, Satoshi ^a   Taniguchi, Natsuko ^a   Makita, Hironi ^a   Nakamaru, Yuji ^a   Shimizu, Kaoruko ^a   Shijubo, Noriharu ^b   Fuke, Satoshi ^c   Takeyabu, Kimihiro ^d   Oguri, Mitsuru ^e   Kimura, Hirokazu ^a   Maeda, Yukiko ^a   Suzuki, Masaru ^a   Nagai, Katsura ^a   Ito, Yoichi M ^f   Wenzel, Sally E ^g   Nishimura, Masaharu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Sapporo General Hospital of Hokkaido Railway Company   (Japan)

^c KKR Sapporo Medical Center   (Japan)

^d Otaru Kyokai Hospital   (Japan)

^e Oji General Hospital   (Japan)

^f HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Cluster analysis; Eosinophils; Phenotypes; Severe asthma; Smoking

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 5; INTERLEUKIN 6; OSTEOPONTIN;

ADULT; AGED; ARTICLE; ASTHMA; CLUSTER ANALYSIS; DISEASE SEVERITY; ENVIRONMENTAL EXPOSURE; EOSINOPHIL; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HOSPITALIZATION; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MOLECULE; OBESITY; PHENOTYPE; SMOKING; SPUTUM ANALYSIS; SPUTUM LEVEL; UNIVERSITY HOSPITAL; ADVERSE EFFECTS; CLINICAL TRIAL; CONTROLLED STUDY; GENETICS; MIDDLE AGED; MULTICENTER STUDY; PATHOLOGY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SEVERITY OF ILLNESS INDEX;

ADULT; AGED; ASTHMA; CLUSTER ANALYSIS; EOSINOPHILS; FEMALE; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SMOKING;

EID: 84950976405     PISSN: 23256621     EISSN: None     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201507-407OC     Document Type: Article

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