메뉴 건너뛰기




Volumn 6, Issue 37, 2015, Pages 39891-39907

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

Author keywords

INPP4B; Melanoma; MiRNA 494; MiRNA 599; SGK3

Indexed keywords

GLUCOCORTICOID REGULATED KINASE 3; INOSITOL POLYPHOSPHATE 4 PHOSPHATASE TYPE II; LENTIVIRUS VECTOR; MICRORNA; MICRORNA 494; MICRORNA 599; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; MIRN494 MICRORNA, HUMAN; MIRN599 MICRORNA, HUMAN; PHOSPHATIDYLINOSITOL-3,4-BISPHOSPHATE 4-PHOSPHATASE; PROTEIN SERINE THREONINE KINASE; SGK3 PROTEIN, HUMAN;

EID: 84950144241     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5359     Document Type: Article
Times cited : (43)

References (55)
  • 2
    • 77954242530 scopus 로고    scopus 로고
    • Molecular circuits of solid tumors: prognostic and predictive tools for bedside use
    • Ferte C, Andre F, Soria JC. Molecular circuits of solid tumors: prognostic and predictive tools for bedside use. Nat Rev Clin Oncol. 2010; 7:367-380.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 367-380
    • Ferte, C.1    Andre, F.2    Soria, J.C.3
  • 5
    • 78651446644 scopus 로고    scopus 로고
    • Hard times for oncogenic BRAF-expressing melanoma cells
    • Houslay MD. Hard times for oncogenic BRAF-expressing melanoma cells. Cancer Cell. 2011; 19:3-4.
    • (2011) Cancer Cell , vol.19 , pp. 3-4
    • Houslay, M.D.1
  • 6
    • 79960027865 scopus 로고    scopus 로고
    • BRAF targeted therapy changes the treatment paradigm in melanoma
    • Ribas A, Flaherty KT. BRAF targeted therapy changes the treatment paradigm in melanoma. Nat Rev Clin Oncol. 2011; 8:426-433.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 426-433
    • Ribas, A.1    Flaherty, K.T.2
  • 7
    • 79951818749 scopus 로고    scopus 로고
    • MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720
    • Jiang CC, Lai F, Thorne RF, Yang F, Liu H, Hersey P, Zhang XD. MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720. Clin Cancer Res. 2011; 17:721-730.
    • (2011) Clin Cancer Res , vol.17 , pp. 721-730
    • Jiang, C.C.1    Lai, F.2    Thorne, R.F.3    Yang, F.4    Liu, H.5    Hersey, P.6    Zhang, X.D.7
  • 10
    • 78651418282 scopus 로고    scopus 로고
    • Mutant BRAF melanomas-dependence and resistance
    • Poulikakos PI, Rosen N. Mutant BRAF melanomas-dependence and resistance. Cancer Cell. 2011; 19:11-15.
    • (2011) Cancer Cell , vol.19 , pp. 11-15
    • Poulikakos, P.I.1    Rosen, N.2
  • 11
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: downstream AKTion blocks apoptosis
    • Franke TF, Kaplan DR, Cantley LC. PI3K: downstream AKTion blocks apoptosis. Cell. 1997; 88:435-437.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 12
    • 0033574526 scopus 로고    scopus 로고
    • The role of phosphatases in inositol signaling reactions
    • Majerus PW, Kisseleva MV, Norris FA. The role of phosphatases in inositol signaling reactions. J Biol Chem. 1999; 274:10669-10672.
    • (1999) J Biol Chem , vol.274 , pp. 10669-10672
    • Majerus, P.W.1    Kisseleva, M.V.2    Norris, F.A.3
  • 13
    • 0035895910 scopus 로고    scopus 로고
    • Phosphatidylinositol 4-phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli
    • Park SJ, Itoh T, Takenawa T. Phosphatidylinositol 4-phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli. J Biol Chem. 2001; 276:4781-4787.
    • (2001) J Biol Chem , vol.276 , pp. 4781-4787
    • Park, S.J.1    Itoh, T.2    Takenawa, T.3
  • 14
    • 63749119765 scopus 로고    scopus 로고
    • PIKKing on PKB: regulation of PKB activity by phosphorylation
    • Bozulic L, Hemmings BA. PIKKing on PKB: regulation of PKB activity by phosphorylation. Curr Opin Cell Biol. 2009; 21:256-261.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 256-261
    • Bozulic, L.1    Hemmings, B.A.2
  • 15
    • 54949109808 scopus 로고    scopus 로고
    • PI3K/Akt: getting it right matters
    • Franke TF. PI3K/Akt: getting it right matters. Oncogene. 2008; 27:6473-6488.
    • (2008) Oncogene , vol.27 , pp. 6473-6488
    • Franke, T.F.1
  • 16
    • 51849097348 scopus 로고    scopus 로고
    • The role of PTEN signaling perturbations in cancer and in targeted therapy
    • Keniry M, Parsons R. The role of PTEN signaling perturbations in cancer and in targeted therapy. Oncogene. 2008; 27:5477-5485.
    • (2008) Oncogene , vol.27 , pp. 5477-5485
    • Keniry, M.1    Parsons, R.2
  • 18
    • 84878398348 scopus 로고    scopus 로고
    • AKT-ing out: SGK kinases come to the fore
    • Moniz LS, Vanhaesebroeck B. AKT-ing out: SGK kinases come to the fore. Biochem J. 2013; 452:e11-13.
    • (2013) Biochem J , vol.452 , pp. e11-e13
    • Moniz, L.S.1    Vanhaesebroeck, B.2
  • 19
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
    • Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol. 2001; 21:952-965.
    • (2001) Mol Cell Biol , vol.21 , pp. 952-965
    • Brunet, A.1    Park, J.2    Tran, H.3    Hu, L.S.4    Hemmings, B.A.5    Greenberg, M.E.6
  • 22
  • 24
    • 33747649796 scopus 로고    scopus 로고
    • Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3
    • Tessier M, Woodgett JR. Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. J Biol Chem. 2006; 281:23978-23989.
    • (2006) J Biol Chem , vol.281 , pp. 23978-23989
    • Tessier, M.1    Woodgett, J.R.2
  • 27
    • 0037155228 scopus 로고    scopus 로고
    • Phosphoinositidespecific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death
    • Kisseleva MV, Cao L, Majerus PW. Phosphoinositidespecific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death. J Biol Chem. 2002; 277:6266-6272.
    • (2002) J Biol Chem , vol.277 , pp. 6266-6272
    • Kisseleva, M.V.1    Cao, L.2    Majerus, P.W.3
  • 28
    • 79551542888 scopus 로고    scopus 로고
    • PTEN level in tumor suppression: how much is too little?
    • Carracedo A, Alimonti A, Polfi PP. PTEN level in tumor suppression: how much is too little?. Cancer Res. 2011; 71:629-633.
    • (2011) Cancer Res , vol.71 , pp. 629-633
    • Carracedo, A.1    Alimonti, A.2    Polfi, P.P.3
  • 29
    • 39149097499 scopus 로고    scopus 로고
    • PI(3, 4, 5)P3 and PI(3, 4)P2 levels correlate with PKB/akt phosphorylation at Thr308 and Ser73, respectively; PI(3, 4)P2 levels determine PKB activity
    • Ma K, Cheung SM, Marshall AJ, Duronio V. PI(3, 4, 5)P3 and PI(3, 4)P2 levels correlate with PKB/akt phosphorylation at Thr308 and Ser73, respectively; PI(3, 4)P2 levels determine PKB activity. Cell Signal. 2008; 20:684-694.
    • (2008) Cell Signal , vol.20 , pp. 684-694
    • Ma, K.1    Cheung, S.M.2    Marshall, A.J.3    Duronio, V.4
  • 37
    • 35448958407 scopus 로고    scopus 로고
    • Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis
    • Jiang CC, Chen LH, Gillespie S, Wang YF, Kiejda KA, Zhang XD, Hersey P. Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis. Cancer Res. 2007; 67:9750-9761.
    • (2007) Cancer Res , vol.67 , pp. 9750-9761
    • Jiang, C.C.1    Chen, L.H.2    Gillespie, S.3    Wang, Y.F.4    Kiejda, K.A.5    Zhang, X.D.6    Hersey, P.7
  • 38
    • 84901191625 scopus 로고    scopus 로고
    • Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma
    • Jiang CC, Croft A, Tseng HY, Guo ST, Jin L, Hersey P, Zhang XD. Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma. Oncogene. 2014; 33:2577-2588.
    • (2014) Oncogene , vol.33 , pp. 2577-2588
    • Jiang, C.C.1    Croft, A.2    Tseng, H.Y.3    Guo, S.T.4    Jin, L.5    Hersey, P.6    Zhang, X.D.7
  • 41
    • 84870063135 scopus 로고    scopus 로고
    • Role of the inositol polyphosphate-4-phosphatase type II Inpp4b in the generation of ovarian teratomas
    • Balakrishnan A, Chaillet JR. Role of the inositol polyphosphate-4-phosphatase type II Inpp4b in the generation of ovarian teratomas. Dev Biol. 2013; 373:118-129.
    • (2013) Dev Biol , vol.373 , pp. 118-129
    • Balakrishnan, A.1    Chaillet, J.R.2
  • 42
    • 67651163588 scopus 로고    scopus 로고
    • Requirement of phosphatidylinositol(3, 4, 5)trisphosphate in phosphatidylinositol 3-kinase-induced oncogenic transformation
    • Denley A, Gymnopoulos M, Kang S, Mitchell C, Vogt PK. Requirement of phosphatidylinositol(3, 4, 5)trisphosphate in phosphatidylinositol 3-kinase-induced oncogenic transformation. Mol Cancer Res. 2009; 7:1132-1138.
    • (2009) Mol Cancer Res , vol.7 , pp. 1132-1138
    • Denley, A.1    Gymnopoulos, M.2    Kang, S.3    Mitchell, C.4    Vogt, P.K.5
  • 43
    • 35548959168 scopus 로고    scopus 로고
    • Gene structure, expression profiling and mutation analysis of the tumour suppressor SHIP1 in Caucasian acute myeloid leukaemia
    • Gilby DC, Goodeve AC, Winship PR, Valk PJ, Delwel R, Reilly JT. Gene structure, expression profiling and mutation analysis of the tumour suppressor SHIP1 in Caucasian acute myeloid leukaemia. Leukemia. 2007; 21:2390-2393.
    • (2007) Leukemia , vol.21 , pp. 2390-2393
    • Gilby, D.C.1    Goodeve, A.C.2    Winship, P.R.3    Valk, P.J.4    Delwel, R.5    Reilly, J.T.6
  • 46
    • 0035871081 scopus 로고    scopus 로고
    • Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
    • Gillooly DJ, Simonsen A, Stenmark H. Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins. Biochem J. 2001; 355:249-258.
    • (2001) Biochem J , vol.355 , pp. 249-258
    • Gillooly, D.J.1    Simonsen, A.2    Stenmark, H.3
  • 47
    • 56949096813 scopus 로고    scopus 로고
    • Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications
    • Rossi S, Sevignani C, Nnadi SC, Siracusa LD, Calin GA. Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications. Mamm Genome. 2008; 19:526-540.
    • (2008) Mamm Genome , vol.19 , pp. 526-540
    • Rossi, S.1    Sevignani, C.2    Nnadi, S.C.3    Siracusa, L.D.4    Calin, G.A.5
  • 49
    • 84872928071 scopus 로고    scopus 로고
    • Epigenetic regulation of miRNA-211 by MMP-9 governs glioma cell apoptosis, chemosensitivity and radiosensitivity
    • Asuthkar S, Velpula KK, Chetty C, Gorantla B, Rao JS. Epigenetic regulation of miRNA-211 by MMP-9 governs glioma cell apoptosis, chemosensitivity and radiosensitivity. Oncotarget. 2012; 3:1439-1454.
    • (2012) Oncotarget , vol.3 , pp. 1439-1454
    • Asuthkar, S.1    Velpula, K.K.2    Chetty, C.3    Gorantla, B.4    Rao, J.S.5
  • 50
    • 84879072759 scopus 로고    scopus 로고
    • Epigenetic regulation of melanoma tumor suppressor miRNA-124a
    • Jazirehi AR, Torres-Collado AX, Nazarian R. Epigenetic regulation of melanoma tumor suppressor miRNA-124a. Epigenomics. 2013; 5:251-252.
    • (2013) Epigenomics , vol.5 , pp. 251-252
    • Jazirehi, A.R.1    Torres-Collado, A.X.2    Nazarian, R.3
  • 51
    • 73349125465 scopus 로고    scopus 로고
    • MicroRNAs in cancer: small molecules with a huge impact
    • Iorio MV, Croce CM. MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol. 2009; 27:5848-5856.
    • (2009) J Clin Oncol , vol.27 , pp. 5848-5856
    • Iorio, M.V.1    Croce, C.M.2
  • 52
    • 60149084560 scopus 로고    scopus 로고
    • MicroRNAs and cancer: short RNAs go a long way
    • Ventura A, Jacks T. MicroRNAs and cancer: short RNAs go a long way. Cell. 2009; 136:586-591.
    • (2009) Cell , vol.136 , pp. 586-591
    • Ventura, A.1    Jacks, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.