The histone methyltransferase inhibitor BIX01294 inhibits HIF-1α stability and angiogenesis

Molecules and Cells

Volumn 38, Issue 6, 2015, Pages 528-534

  Oh, Su Young ^a   Seok, Ji Yoon ^a   Choi, Young Sun ^a   Lee, Sung Hee ^b   Bae, Jong Sup ^a   Lee, You Mie ^a  

^a National Basic Research Laboratory of Vascular Homeostasis Regulation   (South Korea)

^b Kyungpook National University   (South Korea)

Author keywords

Angiogenesis; BIX01294; G9a HMT inhibitor; HIF 1

Indexed keywords

FOCAL ADHESION KINASE; GELATINASE A; HYPOXIA INDUCIBLE FACTOR 1ALPHA; N (1 BENZYL 4 PIPERIDINYL) 2 (HEXAHYDRO 4 METHYL 1H 1,4 DIAZEPIN 1 YL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE; PAXILLIN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE HYDROXYLASE 2; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; VON HIPPEL LINDAU PROTEIN; AZEPINE DERIVATIVE; ENZYME INHIBITOR; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; QUINAZOLINE DERIVATIVE;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CELL HYPOXIA; CELL MIGRATION; CELL PROLIFERATION; CHORIOALLANTOIS; CONTROLLED STUDY; ENZYME INHIBITION; HALF LIFE TIME; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS FIBER; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; CARCINOMA, HEPATOCELLULAR; CHICK EMBRYO; HEP-G2 CELL LINE; LIVER NEOPLASMS; METABOLISM; MOUSE; NEOVASCULARIZATION, PATHOLOGIC; VASCULARIZATION;

ANIMALS; AZEPINES; CARCINOMA, HEPATOCELLULAR; CHICK EMBRYO; ENZYME INHIBITORS; HEP G2 CELLS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER NEOPLASMS; MICE; NEOVASCULARIZATION, PATHOLOGIC; QUINAZOLINES; SIGNAL TRANSDUCTION;

EID: 84950120473     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.14348/molcells.2015.0026     Document Type: Article

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