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Volumn 84, Issue 1, 2010, Pages 47-51

The prolyl-hydroxylase EGLN3 and not EGLN1 is inactivated by methylation in plasma cell neoplasia

Author keywords

EGLN1; EGLN3; Methylation; Multiple myeloma; Plasma cell neoplasia; Prolyl hydroxylase

Indexed keywords

BIOLOGICAL MARKER; EGG LAYING DEFECTIVE NINE 1; EGG LAYING DEFECTIVE NINE 3; GENOMIC DNA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; UNCLASSIFIED DRUG;

EID: 72449141795     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2009.01344.x     Document Type: Article
Times cited : (44)

References (14)
  • 1
    • 33747133256 scopus 로고    scopus 로고
    • Epigenetics: An emerging technology in the diagnosis and treatment of cancer
    • Stebbing J, Bower M, Syed N, Smith P, Yu V, Crook T. Epigenetics: an emerging technology in the diagnosis and treatment of cancer. Pharmacogenomics 2006 7 : 747 757.
    • (2006) Pharmacogenomics , vol.7 , pp. 747-757
    • Stebbing, J.1    Bower, M.2    Syed, N.3    Smith, P.4    Yu, V.5    Crook, T.6
  • 2
    • 36349013133 scopus 로고    scopus 로고
    • Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma
    • Chim CS, Pang R, Fung TK, Choi CL, Liang R. Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma. Leukemia 2007 2 : 2527 2536.
    • (2007) Leukemia , vol.2 , pp. 2527-2536
    • Chim, C.S.1    Pang, R.2    Fung, T.K.3    Choi, C.L.4    Liang, R.5
  • 3
    • 33846878522 scopus 로고    scopus 로고
    • Methylation and expression of the p16INK4A tumor suppressor gene in multiple myeloma
    • Dib A, Barlogie B, Shaughnessy JD Jr., Kuehl WM. Methylation and expression of the p16INK4A tumor suppressor gene in multiple myeloma. Blood 2007 109 : 1337 1338.
    • (2007) Blood , vol.109 , pp. 1337-1338
    • Dib, A.1    Barlogie, B.2    Shaughnessy Jr., J.D.3    Kuehl, W.M.4
  • 5
    • 17944375360 scopus 로고    scopus 로고
    • C. Elegans EGL-9 and mammalian homologs define a family of dioxygenanses that regulate HIF by Prolyl-hydroxylation
    • Epstein AC, Gleadle JM, McNeill LA, et al. C. Elegans EGL-9 and mammalian homologs define a family of dioxygenanses that regulate HIF by Prolyl-hydroxylation. Cell 2001 107 : 43 54.
    • (2001) Cell , vol.107 , pp. 43-54
    • Epstein, A.C.1    Gleadle, J.M.2    McNeill, L.A.3
  • 6
    • 0035812318 scopus 로고    scopus 로고
    • Characterization and comparative analysis of the EGLN gene family
    • Taylor MS. Characterization and comparative analysis of the EGLN gene family. Gene 2001 275 : 125 132.
    • (2001) Gene , vol.275 , pp. 125-132
    • Taylor, M.S.1
  • 7
    • 0036718539 scopus 로고    scopus 로고
    • Molecular basis of the VHL hereditary cancer syndrome
    • Kaelin WG Jr. Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer 2002 2 : 673 682.
    • (2002) Nat Rev Cancer , vol.2 , pp. 673-682
    • Kaelin Jr., W.G.1
  • 8
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia- a key regulatory factor in tumour growth
    • Harris AL. Hypoxia- a key regulatory factor in tumour growth. Nat Rev Cancer 2002 2 : 38 47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 9
    • 23644436667 scopus 로고    scopus 로고
    • Neuronal apoptosis linked to EglN3 prolyl-hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer
    • Lee S, Nakamura E, Yang H, et al. Neuronal apoptosis linked to EglN3 prolyl-hydroxylase and familial pheochromocytoma genes: developmental culling and cancer. Cancer Cell 2005 8 : 91 3.
    • (2005) Cancer Cell , vol.8 , pp. 91-3
    • Lee, S.1    Nakamura, E.2    Yang, H.3
  • 10
    • 41649116940 scopus 로고    scopus 로고
    • The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
    • Schlisio S, Kenchappa RS, Vredeveld LC, et al. The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor. Genes Dev 2008 22 : 884 893.
    • (2008) Genes Dev , vol.22 , pp. 884-893
    • Schlisio, S.1    Kenchappa, R.S.2    Vredeveld, L.C.3
  • 13
    • 58649109828 scopus 로고    scopus 로고
    • Drug discovery for overcoming chronic kidney disease (CKD): Prolyl-hydroxylase inhibitors to activate hypoxia-inducible factor (HIF) as a novel therapeutic approach in CKD
    • Tanaka T, Nangaku M. Drug discovery for overcoming chronic kidney disease (CKD): prolyl-hydroxylase inhibitors to activate hypoxia-inducible factor (HIF) as a novel therapeutic approach in CKD. J Pharmacol Sci 2009 109 : 24 31.
    • (2009) J Pharmacol Sci , vol.109 , pp. 24-31
    • Tanaka, T.1    Nangaku, M.2
  • 14
    • 66149118937 scopus 로고    scopus 로고
    • The Prolyl 3-Hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer
    • Shah R, Smith P, Purdie C, Quinlan P, Baker L, Aman P, Thompson AM, Crook T. The Prolyl 3-Hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer. Br J Cancer 2009 100 : 1687 1696.
    • (2009) Br J Cancer , vol.100 , pp. 1687-1696
    • Shah, R.1    Smith, P.2    Purdie, C.3    Quinlan, P.4    Baker, L.5    Aman, P.6    Thompson, A.M.7    Crook, T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.