An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication

Protein Science

Volumn 24, Issue 9, 2015, Pages 1521-1527

  Barthelme, Dominik ^a   Jauregui, Ruben ^a   Sauer, Robert T ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

AAA+ machine; ATP dependent degradation; proteasome; protein unfolding

Indexed keywords

ASPARAGINE; ASPARTIC ACID; PROTEASOME; PROTEIN P97; ADENOSINE TRIPHOSPHATASE; CDC48 PROTEIN; CELL CYCLE PROTEIN; PROTEIN BINDING;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME BINDING; ENZYME STABILITY; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN MOTIF; PROTEIN UNFOLDING; CHEMISTRY; ENZYMOLOGY; GENETICS; HYDROLYSIS; METABOLISM; MOLECULAR MODEL; PROTEIN TRANSPORT;

ADENOSINE TRIPHOSPHATASES; AMYOTROPHIC LATERAL SCLEROSIS; ASPARTIC ACID; CELL CYCLE PROTEINS; HUMANS; HYDROLYSIS; MODELS, MOLECULAR; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEIN UNFOLDING; PROTEOLYSIS;

EID: 84950107036     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2740     Document Type: Article

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