Peptide-specific T helper cells identified by MHC class II tetramers differentiate into several subtypes upon immunization with CAF01 adjuvanted H56 tuberculosis vaccine formulation

Vaccine

Volumn 33, Issue 48, 2015, Pages 6823-6830

  Prota, Gennaro ^a   Christensen, Dennis ^b   Andersen, Peter ^b   Medaglini, Donata ^a   Ciabattini, Annalisa ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b STATENS SERUM INSTITUT   (Denmark)

Author keywords

CD4+ T cell priming; MHC class II tetramers; Subcutaneous immunization; T helper subsets

Indexed keywords

BACTERIAL ANTIGEN; BCG VACCINE; CAF01 ADJUVANT; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR5; GAMMA INTERFERON; H56 ANTIGEN; HERMES ANTIGEN; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 4; INTERLEUKIN 7 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN BCL 6; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TETRAMER; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; HLA ANTIGEN CLASS 2; SUBUNIT VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL LINEAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG FORMULATION; FEMALE; HELPER CELL; IMMUNIZATION; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL; TUBERCULOSIS; ANIMAL; C57BL MOUSE; IMMUNOLOGY; LUNG; LYMPH NODE; METABOLISM; SPLEEN;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS II; LUNG; LYMPH NODES; MICE, INBRED C57BL; SPLEEN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; TUBERCULOSIS VACCINES; VACCINES, SUBUNIT;

EID: 84949907794     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2015.09.024     Document Type: Article

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