Seipin deficiency increases chromocenter fragmentation and disrupts acrosome formation leading to male infertility

Cell Death and Disease

Volumn 6, Issue 7, 2015, Pages

  El Zowalaty, A E ^a   Baumann, C ^a   Li, R ^a   Chen, W ^b   De La Fuente, R ^a   Ye, X ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; SEIPIN; UNCLASSIFIED DRUG; BSCL2 PROTEIN, MOUSE; CHROMATIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; HISTONE; NUCLEAR PROTEIN; SYCP1 PROTEIN, MOUSE; SYCP3 PROTEIN, MOUSE;

ACROSOME; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CHROMATIN; CHROMATIN CONDENSATION; CHROMOCENTER FRAGMENTATION; CHROMOSOME PAIRING; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; EPIDIDYMIS; FEMALE; MALE; MALE FERTILITY; MALE INFERTILITY; MATING; MEIOTIC RECOMBINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETE TESTIS; SEMINIFEROUS TUBULE; SEMINIFEROUS TUBULE EPITHELIUM; SERTOLI CELL; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; SPERMATOZOON COUNT; SPERMATOZOON MIGRATION; SPERMATOZOON MOTILITY; TESTIS WEIGHT; TRANSCRIPTION INITIATION; X CHROMATIN; ADIPOGENESIS; ANIMAL; BIOSYNTHESIS; CONGENITAL GENERALIZED LIPODYSTROPHY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; PATHOLOGY; TESTIS;

ACROSOME; ADIPOGENESIS; ANIMALS; APOPTOSIS; CHROMATIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HETEROTRIMERIC GTP-BINDING PROTEINS; HISTONES; HUMANS; INFERTILITY, MALE; LIPODYSTROPHY, CONGENITAL GENERALIZED; MALE; NUCLEAR PROTEINS; SERTOLI CELLS; SPERMATIDS; SPERMATOCYTES; SPERMATOGENESIS; TESTIS;

EID: 84949882290     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.188     Document Type: Article

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