-
2
-
-
80052565730
-
Human papillomavirus and rising oropharyngeal cancer incidence in the United States
-
Chaturvedi AK, Engels EA, Pfeiffer RM, et al., Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol 2011; 29: 4294-4301.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4294-4301
-
-
Chaturvedi, A.K.1
Engels, E.A.2
Pfeiffer, R.M.3
-
3
-
-
84855903282
-
Targeting the p53 signaling pathway in cancer therapy - The promises, challenges and perils
-
Stegh AH,. Targeting the p53 signaling pathway in cancer therapy-the promises, challenges and perils. Expert Opin Ther Targets 2012; 16: 67-83.
-
(2012)
Expert Opin Ther Targets
, vol.16
, pp. 67-83
-
-
Stegh, A.H.1
-
4
-
-
84911366969
-
-
National Comprehensive Cancer Network Accessed August 27
-
National Comprehensive Cancer Network. Head and Neck Cancers, version 2.2014. Available at: http://www.nccn.org/professionals/physician-gls/pdf/head-and-neck.pdf. Accessed August 27, 2014.
-
(2014)
Head and Neck Cancers, Version 2.2014
-
-
-
5
-
-
33748164404
-
Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck
-
Colevas AD,. Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 2006; 24: 2644-2652.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2644-2652
-
-
Colevas, A.D.1
-
6
-
-
79958053606
-
Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas
-
Szabó B, Nelhubel GA, Kárpáti A, Kenessey I, Jóri B, Szekely C,. Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas. Oral Oncol 2011; 47: 487-496.
-
(2011)
Oral Oncol
, vol.47
, pp. 487-496
-
-
Szabó, B.1
Nelhubel, G.A.2
Kárpáti, A.3
Kenessey, I.4
Jóri, B.5
Szekely, C.6
-
7
-
-
84896888075
-
Cisplatin, 5-fluorouracil, and cetuximab (PFE) with or without cilengitide in recurrent/metastatic squamous cell carcinoma of the head and neck: Results of the randomized phase I/II ADVANTAGE trial (phase II part)
-
Vermorken JB, Peyrade F, Krauss J, et al., Cisplatin, 5-fluorouracil, and cetuximab (PFE) with or without cilengitide in recurrent/metastatic squamous cell carcinoma of the head and neck: results of the randomized phase I/II ADVANTAGE trial (phase II part). Ann Oncol 2014; 25: 682-688.
-
(2014)
Ann Oncol
, vol.25
, pp. 682-688
-
-
Vermorken, J.B.1
Peyrade, F.2
Krauss, J.3
-
8
-
-
79955496795
-
Evaluation of EGFR gene copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study
-
Licitra L, Mesia R, Rivera F, et al., Evaluation of EGFR gene copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study. Ann Oncol 2011; 22: 1078-1087.
-
(2011)
Ann Oncol
, vol.22
, pp. 1078-1087
-
-
Licitra, L.1
Mesia, R.2
Rivera, F.3
-
9
-
-
84880259398
-
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers
-
Lui VW, Hedberg ML, Li H, et al., Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers. Cancer Discov 2013; 3: 761-769.
-
(2013)
Cancer Discov
, vol.3
, pp. 761-769
-
-
Lui, V.W.1
Hedberg, M.L.2
Li, H.3
-
10
-
-
79952690921
-
PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors
-
Janku F, Tsimberidou AM, Garrido-Laguna I, et al., PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors. Mol Cancer Ther 2011; 10: 558-565.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 558-565
-
-
Janku, F.1
Tsimberidou, A.M.2
Garrido-Laguna, I.3
-
11
-
-
84962072056
-
Loss of PTEN leads to clinical resistance to the PI3Kα inhibitor BYL719 and provides evidence of convergent evolution under selective therapeutic pressure
-
2014; April 5-9, San Diego, CA. Abstract LB-327
-
Castel P, Juric D, Won H, et al., Loss of PTEN leads to clinical resistance to the PI3Kα inhibitor BYL719 and provides evidence of convergent evolution under selective therapeutic pressure. Presented at the American Association for Cancer Research Annual Meeting 2014; April 5-9, 2014; San Diego, CA. Abstract LB-327.
-
(2014)
American Association for Cancer Research Annual Meeting
-
-
Castel, P.1
Juric, D.2
Won, H.3
-
12
-
-
84875475811
-
Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
-
Lyford-Pike S, Peng S, Young GD, et al., Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res 2013; 73: 1733-1741.
-
(2013)
Cancer Res
, vol.73
, pp. 1733-1741
-
-
Lyford-Pike, S.1
Peng, S.2
Young, G.D.3
-
13
-
-
79951906119
-
Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers
-
Von Hoff DD, Stephenson JJ Jr, Rosen P, et al., Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers. J Clin Oncol 2010; 28: 4877-4883.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4877-4883
-
-
Von Hoff, D.D.1
Stephenson, J.J.2
Rosen, P.3
-
14
-
-
84907912530
-
Personalized medicine for patients with advanced cancer in the phase i program at MD Anderson: Validation and landmark analyses
-
Tsimberidou AM, Wen S, Hong DS, et al., Personalized medicine for patients with advanced cancer in the phase I program at MD Anderson: validation and landmark analyses. Clin Cancer Res 2014; 20: 4827-4836.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 4827-4836
-
-
Tsimberidou, A.M.1
Wen, S.2
Hong, D.S.3
-
15
-
-
84928947136
-
-
National Comprehensive Cancer Network Accessed June 1, 2015
-
National Comprehensive Cancer Network. The NCCN Biomarkers Compendium (NCCN Compendium). Available at: http://www.nccn.org/professionals/biomarkers/content/. Accessed June 1, 2015.
-
The NCCN Biomarkers Compendium (NCCN Compendium)
-
-
-
16
-
-
84920370011
-
Molecular profiling of infiltrating urothelial carcinoma of both bladder and non-bladder origin
-
Millis SZ, Bryant D, Basu G, et al., Molecular profiling of infiltrating urothelial carcinoma of both bladder and non-bladder origin. Clin Genitourin Cancer 2015; 13: e37-e49.
-
(2015)
Clin Genitourin Cancer
, vol.13
, pp. e37-e49
-
-
Millis, S.Z.1
Bryant, D.2
Basu, G.3
-
17
-
-
84907960016
-
The mutational spectrum of squamous-cell carcinoma of the head and neck: Targetable genetic events and clinical impact
-
Mountzios G, Rampias T, Psyrri A,. The mutational spectrum of squamous-cell carcinoma of the head and neck: targetable genetic events and clinical impact. Ann Oncol 2014; 25: 1889-1900.
-
(2014)
Ann Oncol
, vol.25
, pp. 1889-1900
-
-
Mountzios, G.1
Rampias, T.2
Psyrri, A.3
-
18
-
-
80052177544
-
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
-
Agrawal N, Frederick MJ, Pickering CR, et al., Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011; 333: 1154-1157.
-
(2011)
Science
, vol.333
, pp. 1154-1157
-
-
Agrawal, N.1
Frederick, M.J.2
Pickering, C.R.3
-
19
-
-
80052158097
-
The mutational landscape of head and neck squamous cell carcinoma
-
Stransky N, Egloff AM, Tward AD, et al., The mutational landscape of head and neck squamous cell carcinoma. Science 2011; 333: 1157-1160.
-
(2011)
Science
, vol.333
, pp. 1157-1160
-
-
Stransky, N.1
Egloff, A.M.2
Tward, A.D.3
-
20
-
-
84923197605
-
Comprehensive genomic characterization of head and neck squamous cell carcinomas
-
Cancer Genome Atlas Network
-
Cancer Genome Atlas Network. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature 2015; 517: 576-582.
-
(2015)
Nature
, vol.517
, pp. 576-582
-
-
-
21
-
-
30344437279
-
Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel
-
Sève P, Mackey J, Isaac S, et al., Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel. Mol Cancer Ther 2005; 4: 2001-2007.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 2001-2007
-
-
Sève, P.1
Mackey, J.2
Isaac, S.3
-
22
-
-
68349103360
-
TLE3 as a candidate biomarker of response to taxane therapy
-
Kulkarni SA, Hicks DG, Watroba NL, et al., TLE3 as a candidate biomarker of response to taxane therapy. Breast Cancer Res 2009; 11: R17.
-
(2009)
Breast Cancer Res
, vol.11
, pp. R17
-
-
Kulkarni, S.A.1
Hicks, D.G.2
Watroba, N.L.3
-
23
-
-
53449098390
-
Predictive value of thymidylate synthase expression in advanced colorectal cancer patients receiving fluoropyrimidine-based chemotherapy: Evidence from 24 studies
-
Qiu LX, Tang QY, Bai JL, et al., Predictive value of thymidylate synthase expression in advanced colorectal cancer patients receiving fluoropyrimidine-based chemotherapy: evidence from 24 studies. Int J Cancer 2008; 123: 2384-2389.
-
(2008)
Int J Cancer
, vol.123
, pp. 2384-2389
-
-
Qiu, L.X.1
Tang, Q.Y.2
Bai, J.L.3
-
24
-
-
84867509337
-
Expression of RRM1 and its association with resistancy to gemcitabine-based chemotherapy in advanced nasopharyngeal carcinoma
-
Zhao LP, Xue C, Zhang JW, et al., Expression of RRM1 and its association with resistancy to gemcitabine-based chemotherapy in advanced nasopharyngeal carcinoma. Chin J Cancer 2012; 31: 476-483.
-
(2012)
Chin J Cancer
, vol.31
, pp. 476-483
-
-
Zhao, L.P.1
Xue, C.2
Zhang, J.W.3
-
25
-
-
77956124352
-
ERCC1 and histopathology in advanced NSCLC patients randomized in a large multicenter phase III trial
-
Vilmar AC, Santoni-Rugiu E, Sørensen JB,. ERCC1 and histopathology in advanced NSCLC patients randomized in a large multicenter phase III trial. Ann Oncol 2010; 21: 1817-1824.
-
(2010)
Ann Oncol
, vol.21
, pp. 1817-1824
-
-
Vilmar, A.C.1
Santoni-Rugiu, E.2
Sørensen, J.B.3
-
26
-
-
33748131278
-
Role of epidermal growth factor receptor pathway-targeted therapy in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck
-
Cohen EE,. Role of epidermal growth factor receptor pathway-targeted therapy in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2006; 24: 2659-2665.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2659-2665
-
-
Cohen, E.E.1
-
27
-
-
84875734469
-
Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: Analysis of data from the EXTREME and CRYSTAL studies
-
Licitra L, Störkel S, Kerr KM, et al., Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: analysis of data from the EXTREME and CRYSTAL studies. Eur J Cancer 2013; 49: 1161-1168.
-
(2013)
Eur J Cancer
, vol.49
, pp. 1161-1168
-
-
Licitra, L.1
Störkel, S.2
Kerr, K.M.3
-
28
-
-
39749097290
-
Role of the MRP1/ABCC1 multidrug transporter protein in cancer
-
Munoz M, Henderson M, Haber M, Norris M,. Role of the MRP1/ABCC1 multidrug transporter protein in cancer. IUBMB Life 2007; 59: 752-757.
-
(2007)
IUBMB Life
, vol.59
, pp. 752-757
-
-
Munoz, M.1
Henderson, M.2
Haber, M.3
Norris, M.4
-
29
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman MM, Pastan I,. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993; 62: 385-427.
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
30
-
-
0037358040
-
Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting p-glycoprotein
-
Thomas H, Coley HM,. Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein. Cancer Control 2003; 10: 159-165.
-
(2003)
Cancer Control
, vol.10
, pp. 159-165
-
-
Thomas, H.1
Coley, H.M.2
-
31
-
-
47149092581
-
Single agent irinotecan for the treatment of metastatic or recurrent squamous carcinoma of the head and neck (SCCHN)
-
Gilbert J, Dang T, Cmelak A, et al., Single agent irinotecan for the treatment of metastatic or recurrent squamous carcinoma of the head and neck (SCCHN). Clin Med Oncol 2007; 1: 59-63.
-
(2007)
Clin Med Oncol
, vol.1
, pp. 59-63
-
-
Gilbert, J.1
Dang, T.2
Cmelak, A.3
-
32
-
-
70350134980
-
SPARC expression correlates with tumor response to albumin-bound paclitaxel in head and neck cancer patients
-
Desai N, Trieu V, Damascelli B, Soon-Shiong P,. SPARC expression correlates with tumor response to albumin-bound paclitaxel in head and neck cancer patients. Transl Oncol 2009; 2: 59-64.
-
(2009)
Transl Oncol
, vol.2
, pp. 59-64
-
-
Desai, N.1
Trieu, V.2
Damascelli, B.3
Soon-Shiong, P.4
-
33
-
-
84898456679
-
MET genetic abnormalities unreliable for patient selection for therapeutic intervention in oropharyngeal squamous cell carcinoma
-
Lacroix L, Post SF, Valent A, et al., MET genetic abnormalities unreliable for patient selection for therapeutic intervention in oropharyngeal squamous cell carcinoma. PLoS One 2014; 9: e84319.
-
(2014)
PLoS One
, vol.9
, pp. e84319
-
-
Lacroix, L.1
Post, S.F.2
Valent, A.3
-
34
-
-
75749109750
-
O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients
-
Spiegl-Kreinecker S, Pirker C, Filipits M, et al., O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients. Neuro Oncol 2010; 12: 28-36.
-
(2010)
Neuro Oncol
, vol.12
, pp. 28-36
-
-
Spiegl-Kreinecker, S.1
Pirker, C.2
Filipits, M.3
-
35
-
-
84856576940
-
RRM1 expression and clinical outcome of gemcitabine-containing chemotherapy for advanced non-small-cell lung cancer: A meta-analysis
-
Gong W, Zhang X, Wu J, et al., RRM1 expression and clinical outcome of gemcitabine-containing chemotherapy for advanced non-small-cell lung cancer: a meta-analysis. Lung Cancer 2012; 75: 374-380.
-
(2012)
Lung Cancer
, vol.75
, pp. 374-380
-
-
Gong, W.1
Zhang, X.2
Wu, J.3
-
36
-
-
84877646733
-
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter
-
Hochhauser D, Glynne-Jones R, Potter V, et al., A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Mol Cancer Ther 2013; 12: 809-818.
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 809-818
-
-
Hochhauser, D.1
Glynne-Jones, R.2
Potter, V.3
-
37
-
-
0028241688
-
A phase II study of gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck
-
Catimel G, Vermorken JB, Clavel M, et al., A phase II study of gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group. Ann Oncol 1994; 5: 543-547.
-
(1994)
EORTC Early Clinical Trials Group. Ann Oncol
, vol.5
, pp. 543-547
-
-
Catimel, G.1
Vermorken, J.B.2
Clavel, M.3
-
38
-
-
23744485834
-
Gemcitabine in the treatment of advanced head and neck cancer
-
Raguse JD, Gath HJ, Bier J, Riess H, Oettle H,. Gemcitabine in the treatment of advanced head and neck cancer. Clin Oncol (R Coll Radiol) 2005; 17: 425-429.
-
(2005)
Clin Oncol (R Coll Radiol)
, vol.17
, pp. 425-429
-
-
Raguse, J.D.1
Gath, H.J.2
Bier, J.3
Riess, H.4
Oettle, H.5
-
39
-
-
0036190848
-
Characterization of the HER-2/neu oncogene by immunohistochemical and fluorescence in situ hybridization analysis in oral and oropharyngeal squamous cell carcinoma
-
Khan AJ, King BL, Smith BD, et al., Characterization of the HER-2/neu oncogene by immunohistochemical and fluorescence in situ hybridization analysis in oral and oropharyngeal squamous cell carcinoma. Clin Cancer Res 2002; 8: 540-548.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 540-548
-
-
Khan, A.J.1
King, B.L.2
Smith, B.D.3
-
40
-
-
84894228106
-
Human epidermal receptor 2-amplified salivary duct carcinoma: Regression with dual human epidermal receptor 2 inhibition and anti-vascular endothelial growth factor combination treatment
-
Falchook GS, Lippman SM, Bastida CC, Kurzrock R,. Human epidermal receptor 2-amplified salivary duct carcinoma: regression with dual human epidermal receptor 2 inhibition and anti-vascular endothelial growth factor combination treatment. Head Neck 2014; 36: E25-E27.
-
(2014)
Head Neck
, vol.36
, pp. E25-E27
-
-
Falchook, G.S.1
Lippman, S.M.2
Bastida, C.C.3
Kurzrock, R.4
-
41
-
-
80052029219
-
Effects of lapatinib monotherapy: Results of a randomised phase II study in therapy-naive patients with locally advanced squamous cell carcinoma of the head and neck
-
Del Campo JM, Hitt R, Sebastian P, et al., Effects of lapatinib monotherapy: results of a randomised phase II study in therapy-naive patients with locally advanced squamous cell carcinoma of the head and neck. Br J Cancer 2011; 105: 618-627.
-
(2011)
Br J Cancer
, vol.105
, pp. 618-627
-
-
Del Campo, J.M.1
Hitt, R.2
Sebastian, P.3
-
42
-
-
84973419516
-
PIK3CA: The most common "targetable" genetic alteration in head and neck cancer - Who might benefit?
-
Chicago, IL
-
Chung CH,. PIK3CA: the most common "targetable" genetic alteration in head and neck cancer-who might benefit? American Society of Clinical Oncology 2015 meeting. Chicago, IL.
-
(2015)
American Society of Clinical Oncology Meeting
-
-
Chung, C.H.1
-
43
-
-
84893249799
-
PI3K and cancer: Lessons, challenges and opportunities
-
Fruman DA, Rommel C,. PI3K and cancer: lessons, challenges and opportunities. Nat Rev Drug Discov 2014; 13: 140-156.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 140-156
-
-
Fruman, D.A.1
Rommel, C.2
-
44
-
-
84895906492
-
Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors
-
Janku F, Hong DS, Fu S, et al., Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors. Cell Rep 2014; 6: 377-387.
-
(2014)
Cell Rep
, vol.6
, pp. 377-387
-
-
Janku, F.1
Hong, D.S.2
Fu, S.3
-
45
-
-
84925500147
-
Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor
-
Juric D, Castel P, Griffith M, et al., Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor. Nature 2015; 518: 240-244.
-
(2015)
Nature
, vol.518
, pp. 240-244
-
-
Juric, D.1
Castel, P.2
Griffith, M.3
-
46
-
-
84901744258
-
RAS/PI3K crosstalk and cetuximab resistance in head and neck squamous cell carcinoma
-
Rampias T, Giagini A, Siolos S, et al., RAS/PI3K crosstalk and cetuximab resistance in head and neck squamous cell carcinoma. Clin Cancer Res 2014; 20: 2933-2946.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2933-2946
-
-
Rampias, T.1
Giagini, A.2
Siolos, S.3
-
47
-
-
84929453705
-
MTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations
-
Wang Z, Martin D, Molinolo AA, et al., mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations. J Natl Cancer Inst 2014; 106: 215.
-
(2014)
J Natl Cancer Inst
, vol.106
, pp. 215
-
-
Wang, Z.1
Martin, D.2
Molinolo, A.A.3
-
48
-
-
84925534104
-
Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21 days or q28 days) for patients with advanced solid tumors
-
Hyman DM, Snyder AE, Carvajal RD, et al., Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21 days or q28 days) for patients with advanced solid tumors. Cancer Chemother Pharmacol 2015; 75: 747-755.
-
(2015)
Cancer Chemother Pharmacol
, vol.75
, pp. 747-755
-
-
Hyman, D.M.1
Snyder, A.E.2
Carvajal, R.D.3
-
49
-
-
45749127481
-
Predictive biomarkers of chemotherapy efficacy in colorectal cancer: Results from the UK MRC FOCUS trial
-
Braun MS, Richman SD, Quirke P, et al., Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial. J Clin Oncol 2008; 26: 2690-2698.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2690-2698
-
-
Braun, M.S.1
Richman, S.D.2
Quirke, P.3
-
50
-
-
33644753906
-
Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel
-
Desai N, Trieu V, Yao Z, et al., Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel. Clin Cancer Res 2006; 12: 1317-1324.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1317-1324
-
-
Desai, N.1
Trieu, V.2
Yao, Z.3
-
51
-
-
79954443733
-
Response to temozolomide in patients with metastatic colorectal cancer with loss of MGMT expression: A new approach in the era of personalized medicine?
-
Shacham-Shmueli E, Beny A, Geva R, Blachar A, Figer A, Aderka D,. Response to temozolomide in patients with metastatic colorectal cancer with loss of MGMT expression: a new approach in the era of personalized medicine? J Clin Oncol 2011; 29: e262-e265.
-
(2011)
J Clin Oncol
, vol.29
, pp. e262-e265
-
-
Shacham-Shmueli, E.1
Beny, A.2
Geva, R.3
Blachar, A.4
Figer, A.5
Aderka, D.6
-
52
-
-
84961289657
-
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas
-
Seiwert TY, Zuo Z, Keck MK, et al., Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas. Clin Cancer Res 2015; 21: 632-641.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 632-641
-
-
Seiwert, T.Y.1
Zuo, Z.2
Keck, M.K.3
-
53
-
-
84874327940
-
Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes
-
Walter V, Yin X, Wilkerson MD, et al., Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes. PLoS One 2013; 8: e56823.
-
(2013)
PLoS One
, vol.8
, pp. e56823
-
-
Walter, V.1
Yin, X.2
Wilkerson, M.D.3
-
54
-
-
84879785532
-
Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): An open-label phase 3 randomised trial
-
Vermorken JB, Stöhlmacher-Williams J, Davidenko I, et al., Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial. Lancet Oncol 2013; 14: 697-710.
-
(2013)
Lancet Oncol
, vol.14
, pp. 697-710
-
-
Vermorken, J.B.1
Stöhlmacher-Williams, J.2
Davidenko, I.3
-
55
-
-
84897101976
-
Impact of tumor HPV status on outcome in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck receiving chemotherapy with or without cetuximab: Retrospective analysis of the phase III EXTREME trial
-
Vermorken JB, Psyrri A, Mesía R, et al., Impact of tumor HPV status on outcome in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck receiving chemotherapy with or without cetuximab: retrospective analysis of the phase III EXTREME trial. Ann Oncol 2014; 25: 801-807.
-
(2014)
Ann Oncol
, vol.25
, pp. 801-807
-
-
Vermorken, J.B.1
Psyrri, A.2
Mesía, R.3
-
56
-
-
84973421703
-
Activity of cetuximab (C) in head and neck squamous cell carcinoma (HNSCC) patients (pts) with PTEN loss or PIK3CA mutation treated on E5397, a phase III trial of cisplatin (CDDP) with placebo (P) or C
-
Chicago, IL
-
Burtness B,. Activity of cetuximab (C) in head and neck squamous cell carcinoma (HNSCC) patients (pts) with PTEN loss or PIK3CA mutation treated on E5397, a phase III trial of cisplatin (CDDP) with placebo (P) or C. American Society of Clinical Oncology 2013 meeting. Chicago, IL.
-
(2013)
American Society of Clinical Oncology Meeting
-
-
Burtness, B.1
-
57
-
-
84945457124
-
Epidermal growth factor receptor P753S mutation in cutaneous squamous cell carcinoma responsive to cetuximab-based therapy
-
[Epub ahead of print]
-
Ganesan P, Ali SM, Wang K, et al., Epidermal growth factor receptor P753S mutation in cutaneous squamous cell carcinoma responsive to cetuximab-based therapy. J Clin Oncol 2014. [Epub ahead of print].
-
(2014)
J Clin Oncol
-
-
Ganesan, P.1
Ali, S.M.2
Wang, K.3
-
58
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al., Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366: 2443-2454.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
|