Study of GABA in healthy volunteers: Pharmacokinetics and pharmacodynamics

Frontiers in Pharmacology

Volumn 6, Issue NOV, 2015, Pages

  Li, Junfeng ^a,g   Zhang, Zhaoyun ^a   Liu, Xiaoxia ^a   Wang, Yi ^a   Mao, Fei ^a   Mao, Junjun ^a   Lu, Xiaolan ^a   Jiang, Dongdong ^a   Wan, Yun ^a   Lv, Jia Ying ^b   Cao, Guoying ^a   Zhang, Jing ^a   Zhao, Naiqing ^b   Atkinson, Mark ^c   Greiner, Dale L ^d   Prud'homme, Gerald J ^e   Jiao, Zheng ^a   Li, Yiming ^a   Wang, Qinghua ^a,e,f  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^e ST MICHAEL'S HOSPITAL   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

^g RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

GABA; Glucagon; Glycated albumin; Insulin; Pharmacokinetics

Indexed keywords

4 AMINOBUTYRIC ACID; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; C PEPTIDE; GLUCAGON; GLYCOSYLATED ALBUMIN; INSULIN; PLACEBO;

ADULT; AREA UNDER THE CURVE; ARTICLE; BURNING SENSATION; CHEST STIFFNESS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG SAFETY; DRUG TOLERABILITY; DRY PHARYNX; ELIMINATION HALF-LIFE; FATIGUE; FEMALE; GLUCOSE BLOOD LEVEL; HEADACHE; HEART PALPITATION; HUMAN; HUMAN EXPERIMENT; INSULIN RELEASE; JAW PAIN; LIMB PAIN; MALE; MAXIMUM PLASMA CONCENTRATION; NECK PAIN; NORMAL HUMAN; PARESTHESIA; PHARYNX DISEASE; POLYDIPSIA; PROTEIN SECRETION; SINGLE DRUG DOSE; SKIN BURNING SENSATION; SKIN DISEASE; SKIN NEEDLING SENSATION; SLEEP DISORDER; SORE THROAT; THORAX DISEASE; THROAT BURNING; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT DURATION;

EID: 84949780154     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00260     Document Type: Article

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