메뉴 건너뛰기




Volumn 6, Issue NOV, 2015, Pages

Exploring amino acid auxotrophy in Bifidobacterium bifidum PRL2010

Author keywords

Bifidobacteria; Chemically defined medium; Genomics; Microbiota

Indexed keywords

CASEIN HYDROLYSATE; CYSTEINE; GLUTATHIONE; METHIONINE; NITROGEN;

EID: 84949752916     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.01331     Document Type: Article
Times cited : (47)

References (43)
  • 1
    • 84922920926 scopus 로고    scopus 로고
    • CysB-dependent upregulation of the Salmonella Typhimurium cysJIH operon in response to antimicrobial compounds that induce oxidative stress
    • Alvarez, R., Neumann, G., Fravega, J., Diaz, F., Tejias, C., Collao, B., et al. (2015). CysB-dependent upregulation of the Salmonella Typhimurium cysJIH operon in response to antimicrobial compounds that induce oxidative stress. Biochem. Biophys. Res. Commun. 458, 46-51. doi: 10.1016/j.bbrc.2015.01.058
    • (2015) Biochem. Biophys. Res. Commun , vol.458 , pp. 46-51
    • Alvarez, R.1    Neumann, G.2    Fravega, J.3    Diaz, F.4    Tejias, C.5    Collao, B.6
  • 2
    • 77956476472 scopus 로고    scopus 로고
    • Global regulation of gene expression in response to cysteine availability in Clostridium perfringens
    • Andre, G., Haudecoeur, E., Monot, M., Ohtani, K., Shimizu, T., Dupuy, B., et al. (2010). Global regulation of gene expression in response to cysteine availability in Clostridium perfringens. BMC Microbiol. 10:234. doi: 10.1186/1471-2180-10-234
    • (2010) BMC Microbiol , vol.10 , pp. 234
    • Andre, G.1    Haudecoeur, E.2    Monot, M.3    Ohtani, K.4    Shimizu, T.5    Dupuy, B.6
  • 3
    • 84863845475 scopus 로고    scopus 로고
    • CysK from Lactobacillus casei encodes a protein with O-acetylserine sulfhydrylase and cysteine desulfurization activity
    • Bogicevic, B., Berthoud, H., Portmann, R., Meile, L., and Irmler, S. (2012). CysK from Lactobacillus casei encodes a protein with O-acetylserine sulfhydrylase and cysteine desulfurization activity. Appl. Microbiol. Biotechnol. 94, 1209-1220. doi: 10.1007/s00253-011-3677-5
    • (2012) Appl. Microbiol. Biotechnol , vol.94 , pp. 1209-1220
    • Bogicevic, B.1    Berthoud, H.2    Portmann, R.3    Meile, L.4    Irmler, S.5
  • 4
    • 3242759038 scopus 로고    scopus 로고
    • Three different systems participate in L-cystine uptake in Bacillus subtilis
    • Burguiere, P., Auger, S., Hullo, M. F., Danchin, A., and Martin-Verstraete, I. (2004). Three different systems participate in L-cystine uptake in Bacillus subtilis. J. Bacteriol. 186, 4875-4884. doi: 10.1128/JB.186.15.4875-4884.2004
    • (2004) J. Bacteriol , vol.186 , pp. 4875-4884
    • Burguiere, P.1    Auger, S.2    Hullo, M.F.3    Danchin, A.4    Martin-Verstraete, I.5
  • 5
    • 84870916445 scopus 로고    scopus 로고
    • Microbial pathways in colonic sulfur metabolism and links with health and disease
    • Carbonero, F., Benefiel, A. C., Alizadeh-Ghamsari, A. H., and Gaskins, H. R. (2012). Microbial pathways in colonic sulfur metabolism and links with health and disease. Front. Physiol. 3:448. doi: 10.3389/fphys.2012.00448
    • (2012) Front. Physiol , vol.3 , pp. 448
    • Carbonero, F.1    Benefiel, A.C.2    Alizadeh-Ghamsari, A.H.3    Gaskins, H.R.4
  • 6
    • 84862737741 scopus 로고    scopus 로고
    • Identification of iron-regulated genes of Bifidobacterium breve UCC2003 as a basis for controlled gene expression
    • Cronin, M., Zomer, A., Fitzgerald, G. F., and van Sinderen, D. (2012). Identification of iron-regulated genes of Bifidobacterium breve UCC2003 as a basis for controlled gene expression. Bioeng. Bugs 3, 157-167. doi: 10.4161/bbug.18985
    • (2012) Bioeng. Bugs , vol.3 , pp. 157-167
    • Cronin, M.1    Zomer, A.2    Fitzgerald, G.F.3    van Sinderen, D.4
  • 7
    • 84872291131 scopus 로고    scopus 로고
    • Intestinal luminal nitrogen metabolism: role of the gut microbiota and consequences for the host
    • Davila, A. M., Blachier, F., Gotteland, M., Andriamihaja, M., Benetti, P. H., Sanz, Y., et al. (2013). Intestinal luminal nitrogen metabolism: role of the gut microbiota and consequences for the host. Pharmacol. Res. 68, 95-107. doi: 10.1016/j.phrs.2012.11.005
    • (2013) Pharmacol. Res , vol.68 , pp. 95-107
    • Davila, A.M.1    Blachier, F.2    Gotteland, M.3    Andriamihaja, M.4    Benetti, P.H.5    Sanz, Y.6
  • 8
    • 84937073639 scopus 로고    scopus 로고
    • Insights from genomes of representatives of the human gut commensal Bifidobacterium bifidum
    • Duranti, S., Milani, C., Lugli, G. A., Turroni, F., Mancabelli, L., Sanchez, B., et al. (2015). Insights from genomes of representatives of the human gut commensal Bifidobacterium bifidum. Environ. Microbiol. 17, 2515-2531. doi: 10.1111/1462-2920.12743
    • (2015) Environ. Microbiol , vol.17 , pp. 2515-2531
    • Duranti, S.1    Milani, C.2    Lugli, G.A.3    Turroni, F.4    Mancabelli, L.5    Sanchez, B.6
  • 9
  • 10
    • 84857128238 scopus 로고    scopus 로고
    • Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection
    • Fanning, S., Hall, L. J., Cronin, M., Zomer, A., MacSharry, J., Goulding, D., et al. (2012). Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection. Proc. Natl. Acad. Sci. U.S.A. 109, 2108-2113. doi: 10.1073/pnas.1115621109
    • (2012) Proc. Natl. Acad. Sci. U.S.A , vol.109 , pp. 2108-2113
    • Fanning, S.1    Hall, L.J.2    Cronin, M.3    Zomer, A.4    MacSharry, J.5    Goulding, D.6
  • 11
    • 0036134771 scopus 로고    scopus 로고
    • Regulation of the metC-cysK operon, involved in sulfur metabolism in Lactococcus lactis
    • Fernandez, M., Kleerebezem, M., Kuipers, O. P., Siezen, R. J., and van Kranenburg, R. (2002). Regulation of the metC-cysK operon, involved in sulfur metabolism in Lactococcus lactis. J. Bacteriol. 184, 82-90. doi: 10.1128/JB.184.1.82-90.2002
    • (2002) J. Bacteriol , vol.184 , pp. 82-90
    • Fernandez, M.1    Kleerebezem, M.2    Kuipers, O.P.3    Siezen, R.J.4    van Kranenburg, R.5
  • 12
    • 0032950276 scopus 로고    scopus 로고
    • Regulation of nitrogen metabolism in Bacillus subtilis: vive la difference!
    • Fisher, S. H. (1999). Regulation of nitrogen metabolism in Bacillus subtilis: vive la difference! Mol. Microbiol. 32, 223-232. doi: 10.1046/j.1365-2958.1999.01333.x
    • (1999) Mol. Microbiol , vol.32 , pp. 223-232
    • Fisher, S.H.1
  • 13
    • 0027399530 scopus 로고
    • Identification of protein coding regions by database similarity search
    • Gish, W., and States, D. J. (1993). Identification of protein coding regions by database similarity search. Nat. Genet. 3, 266-272. doi: 10.1038/ng0393-266
    • (1993) Nat. Genet , vol.3 , pp. 266-272
    • Gish, W.1    States, D.J.2
  • 15
    • 0026738588 scopus 로고
    • The molecular-basis for positive regulation of Cys promoters in Salmonella-Typhimurium and Escherichia-Coli
    • Kredich, N. M. (1992). The molecular-basis for positive regulation of Cys promoters in Salmonella-Typhimurium and Escherichia-Coli. Mol. Microbiol. 6, 2747-2753. doi: 10.1111/j.1365-2958.1992.tb01453.x
    • (1992) Mol. Microbiol , vol.6 , pp. 2747-2753
    • Kredich, N.M.1
  • 16
    • 33846632778 scopus 로고    scopus 로고
    • Functional analysis of luxS in the probiotic strain Lactobacillus rhamnosus GG reveals a central metabolic role important for growth and Biofilm formation
    • Lebeer, S., De Keersmaecker, S. C. J., Verhoeven, T. L. A., Fadda, A. A., Marchal, K., and Vanderleyden, J. (2007). Functional analysis of luxS in the probiotic strain Lactobacillus rhamnosus GG reveals a central metabolic role important for growth and Biofilm formation. J. Bacteriol. 189, 860-871. doi: 10.1128/Jb.01394-06
    • (2007) J. Bacteriol , vol.189 , pp. 860-871
    • Lebeer, S.1    De Keersmaecker, S.C.J.2    Verhoeven, T.L.A.3    Fadda, A.A.4    Marchal, K.5    Vanderleyden, J.6
  • 17
    • 0036161994 scopus 로고    scopus 로고
    • Human milk provides peptides highly stimulating the growth of bifidobacteria
    • Liepke, C., Adermann, K., Raida, M., Magert, H. J., Forssmann, W. G., and Zucht, H. D. (2002). Human milk provides peptides highly stimulating the growth of bifidobacteria. Eur. J. Biochem. 269, 712-718. doi: 10.1046/j.0014-2956.2001.02712.x
    • (2002) Eur. J. Biochem , vol.269 , pp. 712-718
    • Liepke, C.1    Adermann, K.2    Raida, M.3    Magert, H.J.4    Forssmann, W.G.5    Zucht, H.D.6
  • 18
    • 84864001540 scopus 로고    scopus 로고
    • Computational analysis of cysteine and methionine metabolism and its regulation in dairy starter and related bacteria
    • Liu, M. J., Prakash, C., Nauta, A., Siezen, R. J., and Francke, C. (2012). Computational analysis of cysteine and methionine metabolism and its regulation in dairy starter and related bacteria. J. Bacteriol. 194, 3522-3533. doi: 10.1128/JB.06816-11
    • (2012) J. Bacteriol , vol.194 , pp. 3522-3533
    • Liu, M.J.1    Prakash, C.2    Nauta, A.3    Siezen, R.J.4    Francke, C.5
  • 19
    • 84874618740 scopus 로고    scopus 로고
    • Bioactive proteins in breast milk
    • Lonnerdal, B. (2013). Bioactive proteins in breast milk. J. Paediatr. Child Health 49, 1-7. doi: 10.1111/jpc.12104
    • (2013) J. Paediatr. Child Health , vol.49 , pp. 1-7
    • Lonnerdal, B.1
  • 20
    • 84907267761 scopus 로고    scopus 로고
    • Investigation of the evolutionary development of the genus Bifidobacterium by comparative genomics
    • Lugli, G. A., Milani, C., Turroni, F., Duranti, S., Ferrario, C., Viappiani, A., et al. (2014). Investigation of the evolutionary development of the genus Bifidobacterium by comparative genomics. Appl. Environ. Microbiol. 80, 6383-6394. doi: 10.1128/AEM.02004-14
    • (2014) Appl. Environ. Microbiol , vol.80 , pp. 6383-6394
    • Lugli, G.A.1    Milani, C.2    Turroni, F.3    Duranti, S.4    Ferrario, C.5    Viappiani, A.6
  • 21
    • 0034037189 scopus 로고    scopus 로고
    • The Bacillus subtilis cysP gene encodes a novel sulphate permease related to the inorganic phosphate transporter (Pit) family
    • Mansilla, M. C., and de Mendoza, D. (2000). The Bacillus subtilis cysP gene encodes a novel sulphate permease related to the inorganic phosphate transporter (Pit) family. Microbiology 146(Pt 4), 815-821. doi: 10.1099/00221287-146-4-815
    • (2000) Microbiology , vol.146 , pp. 815-821
    • Mansilla, M.C.1    de Mendoza, D.2
  • 22
    • 84880958392 scopus 로고    scopus 로고
    • A refined palate: bacterial consumption of host glycans in the gut
    • Marcobal, A., Southwick, A. M., Earle, K. A., and Sonnenburg, J. L. (2013). A refined palate: bacterial consumption of host glycans in the gut. Glycobiology 23, 1038-1046. doi: 10.1093/glycob/cwt040
    • (2013) Glycobiology , vol.23 , pp. 1038-1046
    • Marcobal, A.1    Southwick, A.M.2    Earle, K.A.3    Sonnenburg, J.L.4
  • 23
    • 30344443092 scopus 로고    scopus 로고
    • Isolation and characterisation of a novel antibacterial peptide from bovine alpha(s1)-casein
    • McCann, K. B., Shiell, B. J., Michalski, W. P., Lee, A., Wan, J., Roginski, H., et al. (2006). Isolation and characterisation of a novel antibacterial peptide from bovine alpha(s1)-casein. Int. Dairy J. 16, 316-323. doi: 10.1016/j.idairyl.2005.05.005
    • (2006) Int. Dairy J , vol.16 , pp. 316-323
    • McCann, K.B.1    Shiell, B.J.2    Michalski, W.P.3    Lee, A.4    Wan, J.5    Roginski, H.6
  • 24
    • 0037209757 scopus 로고    scopus 로고
    • Bacterial cysteine desulfurases: their function and mechanisms
    • Mihara, H., and Esaki, N. (2002). Bacterial cysteine desulfurases: their function and mechanisms. Appl. Microbiol. Biotechnol. 60, 12-23. doi: 10.1007/s00253-002-1107-4
    • (2002) Appl. Microbiol. Biotechnol , vol.60 , pp. 12-23
    • Mihara, H.1    Esaki, N.2
  • 26
    • 79952035291 scopus 로고    scopus 로고
    • Bioactive peptides derived from milk proteins and their health beneficial potentials: an update
    • Nagpal, R., Behare, P., Rana, R., Kumar, A., Kumar, M., Arora, S., et al. (2011). Bioactive peptides derived from milk proteins and their health beneficial potentials: an update. Food Funct. 2, 18-27. doi: 10.1039/c0fo00016g
    • (2011) Food Funct , vol.2 , pp. 18-27
    • Nagpal, R.1    Behare, P.2    Rana, R.3    Kumar, A.4    Kumar, M.5    Arora, S.6
  • 27
    • 79960586903 scopus 로고    scopus 로고
    • Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor
    • O'Connell Motherway, M., Zomer, A., Leahy, S. C., Reunanen, J., Bottacini, F., Claesson, M. J., et al. (2011). Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor. Proc. Natl. Acad. Sci. U.S.A. 108, 11217-11222. doi: 10.1073/pnas.1105380108
    • (2011) Proc. Natl. Acad. Sci. U.S.A , vol.108 , pp. 11217-11222
    • O'Connell Motherway, M.1    Zomer, A.2    Leahy, S.C.3    Reunanen, J.4    Bottacini, F.5    Claesson, M.J.6
  • 28
    • 0033856892 scopus 로고    scopus 로고
    • Factors affecting exocellular polysaccharide production by Lactobacillus delbrueckii subsp bulgaricus grown in a chemically defined medium
    • Petry, S., Furlan, S., Crepeau, M. J., Cerning, J., and Desmazeaud, M. (2000). Factors affecting exocellular polysaccharide production by Lactobacillus delbrueckii subsp bulgaricus grown in a chemically defined medium. Appl. Environ. Microbiol. 66, 3427-3431. doi: 10.1128/AEM.66.8.3427-3431.2000
    • (2000) Appl. Environ. Microbiol , vol.66 , pp. 3427-3431
    • Petry, S.1    Furlan, S.2    Crepeau, M.J.3    Cerning, J.4    Desmazeaud, M.5
  • 29
    • 0003110584 scopus 로고
    • Bovine-milk kappa-casein trypsin digest is a growth enhancer for the genus Bifidobacterium
    • Poch, M., and Bezkorovainy, A. (1991). Bovine-milk kappa-casein trypsin digest is a growth enhancer for the genus Bifidobacterium. J. Agric. Food Chem. 39, 73-77. doi: 10.1021/jf00001a013
    • (1991) J. Agric. Food Chem , vol.39 , pp. 73-77
    • Poch, M.1    Bezkorovainy, A.2
  • 30
    • 80054971682 scopus 로고    scopus 로고
    • Carbohydrate metabolism in Bifidobacteria
    • Pokusaeva, K., Fitzgerald, G. F., and van Sinderen, D. (2011). Carbohydrate metabolism in Bifidobacteria. Genes Nutr. 6, 285-306. doi: 10.1007/s12263-010-0206-6
    • (2011) Genes Nutr , vol.6 , pp. 285-306
    • Pokusaeva, K.1    Fitzgerald, G.F.2    van Sinderen, D.3
  • 31
    • 0000030639 scopus 로고    scopus 로고
    • Biology and origin of bioactive peptides in milk
    • Schanbacher, F. L., Talhouk, R. S., and Murray, F. A. (1997). Biology and origin of bioactive peptides in milk. Livestock Prod. Sci. 50, 105-123. doi: 10.1016/j.ijfoodmicro.2013.06.019
    • (1997) Livestock Prod. Sci , vol.50 , pp. 105-123
    • Schanbacher, F.L.1    Talhouk, R.S.2    Murray, F.A.3
  • 32
    • 84936973019 scopus 로고    scopus 로고
    • CysK plays a role in biofilm formation and colonization by Vibrio fischeri
    • Singh, P., Brooks, J. F. II, Ray, V. A., Mandel, M. J., and Visick, K. L. (2015). CysK plays a role in biofilm formation and colonization by Vibrio fischeri. Appl. Environ. Microbiol. 81, 5223-5234. doi: 10.1128/AEM.00157-15
    • (2015) Appl. Environ. Microbiol , vol.81 , pp. 5223-5234
    • Singh, P.1    Brooks, J.F.2    Ray, V.A.3    Mandel, M.J.4    Visick, K.L.5
  • 33
    • 78650609691 scopus 로고    scopus 로고
    • Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging
    • Turroni, F., Bottacini, F., Foroni, E., Mulder, I., Kim, J. H., Zomer, A., et al. (2010). Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging. Proc. Natl. Acad. Sci. U.S.A. 107, 19514-19519. doi: 10.1073/pnas.1011100107
    • (2010) Proc. Natl. Acad. Sci. U.S.A , vol.107 , pp. 19514-19519
    • Turroni, F.1    Bottacini, F.2    Foroni, E.3    Mulder, I.4    Kim, J.H.5    Zomer, A.6
  • 34
    • 83155193029 scopus 로고    scopus 로고
    • Global genome transcription profiling of Bifidobacterium bifidum PRL2010 under in vitro conditions and identification of reference genes for quantitative real-time PCR
    • Turroni, F., Foroni, E., Montanini, B., Viappiani, A., Strati, F., Duranti, S., et al. (2011). Global genome transcription profiling of Bifidobacterium bifidum PRL2010 under in vitro conditions and identification of reference genes for quantitative real-time PCR. Appl. Environ. Microbiol. 77, 8578-8587. doi: 10.1128/AEM.06352-11
    • (2011) Appl. Environ. Microbiol , vol.77 , pp. 8578-8587
    • Turroni, F.1    Foroni, E.2    Montanini, B.3    Viappiani, A.4    Strati, F.5    Duranti, S.6
  • 35
    • 84861011960 scopus 로고    scopus 로고
    • Diversity of bifidobacteria within the infant gut microbiota
    • Turroni, F., Peano, C., Pass, D. A., Foroni, E., Severgnini, M., Claesson, M. J., et al. (2012a). Diversity of bifidobacteria within the infant gut microbiota. PLoS ONE 7:e36957. doi: 10.1371/journal.pone.0036957
    • (2012) PLoS ONE , vol.7
    • Turroni, F.1    Peano, C.2    Pass, D.A.3    Foroni, E.4    Severgnini, M.5    Claesson, M.J.6
  • 36
    • 84863738705 scopus 로고    scopus 로고
    • Analysis of predicted carbohydrate transport systems encoded by Bifidobacterium bifidum PRL2010
    • Turroni, F., Strati, F., Foroni, E., Serafini, F., Duranti, S., van Sinderen, D., et al. (2012b). Analysis of predicted carbohydrate transport systems encoded by Bifidobacterium bifidum PRL2010. Appl. Environ. Microbiol. 78, 5002-5012. doi: 10.1128/AEM.00629-12
    • (2012) Appl. Environ. Microbiol , vol.78 , pp. 5002-5012
    • Turroni, F.1    Strati, F.2    Foroni, E.3    Serafini, F.4    Duranti, S.5    van Sinderen, D.6
  • 37
    • 84879700369 scopus 로고    scopus 로고
    • Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium-host interactions
    • Turroni, F., Serafini, F., Foroni, E., Duranti, S., O'Connell Motherway, M., Taverniti, V., et al. (2013). Role of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in modulating bacterium-host interactions. Proc. Natl. Acad. Sci. U.S.A. 110, 11151-11156. doi: 10.1073/pnas.1303897110
    • (2013) Proc. Natl. Acad. Sci. U.S.A , vol.110 , pp. 11151-11156
    • Turroni, F.1    Serafini, F.2    Foroni, E.3    Duranti, S.4    O'Connell Motherway, M.5    Taverniti, V.6
  • 39
    • 84920621534 scopus 로고    scopus 로고
    • Bifidobacterium longum subspecies infantis: champion colonizer of the infant gut
    • Underwood, M. A., German, J. B., Lebrilla, C. B., and Mills, D. A. (2015). Bifidobacterium longum subspecies infantis: champion colonizer of the infant gut. Pediatr. Res. 77, 229-235. doi: 10.1038/pr.2014.156
    • (2015) Pediatr. Res , vol.77 , pp. 229-235
    • Underwood, M.A.1    German, J.B.2    Lebrilla, C.B.3    Mills, D.A.4
  • 40
    • 0031665131 scopus 로고    scopus 로고
    • Bacillus subtilis genes for the utilization of sulfur from aliphatic sulfonates
    • van der Ploeg, J. R., Cummings, N. J., Leisinger, T., and Connerton, I. F. (1998). Bacillus subtilis genes for the utilization of sulfur from aliphatic sulfonates. Microbiology 144(Pt 9), 2555-2561. doi: 10.1099/00221287-144-9-2555
    • (1998) Microbiology , vol.144 , pp. 2555-2561
    • van der Ploeg, J.R.1    Cummings, N.J.2    Leisinger, T.3    Connerton, I.F.4
  • 41
    • 84866895877 scopus 로고    scopus 로고
    • Host-microbe interactions that facilitate gut colonization by commensal bifidobacteria
    • Ventura, M., Turroni, F., Motherway, M. O., MacSharry, J., and van Sinderen, D. (2012). Host-microbe interactions that facilitate gut colonization by commensal bifidobacteria. Trends Microbiol. 20, 467-476. doi: 10.1016/j.tim.2012.07.002
    • (2012) Trends Microbiol , vol.20 , pp. 467-476
    • Ventura, M.1    Turroni, F.2    Motherway, M.O.3    MacSharry, J.4    van Sinderen, D.5
  • 42
    • 41649115061 scopus 로고    scopus 로고
    • Comparative genomic analysis of T-box regulatory systems in bacteria
    • Vitreschak, A. G., Mironov, A. A., Lyubetsky, V. A., and Gelfand, M. S. (2008). Comparative genomic analysis of T-box regulatory systems in bacteria. RNA 14, 717-735. doi: 10.1261/rna.819308
    • (2008) RNA , vol.14 , pp. 717-735
    • Vitreschak, A.G.1    Mironov, A.A.2    Lyubetsky, V.A.3    Gelfand, M.S.4
  • 43
    • 84862245279 scopus 로고    scopus 로고
    • Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction
    • Ye, J., Coulouris, G., Zaretskaya, I., Cutcutache, I., Rozen, S., and Madden, T. L. (2012). Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction. BMC Bioinform. 13:134. doi: 10.1186/1471-2105-13-134
    • (2012) BMC Bioinform , vol.13 , pp. 134
    • Ye, J.1    Coulouris, G.2    Zaretskaya, I.3    Cutcutache, I.4    Rozen, S.5    Madden, T.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.