Bioactive proteins in breast milk

Journal of Paediatrics and Child Health

Volumn 49, Issue SUPPL. 1, 2013, Pages 1-7

  Lönnerdal, Bo ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

bioactive; human; infant formula; milk; prebiotics; protein; recombinant protein

Indexed keywords

ALPHA LACTALBUMIN; BILE SALT; CASEIN; HAPTOCORRIN; LACTOFERRIN; LACTOPEROXIDASE; LIPASE B; LYSOZYME; MILK FAT; MILK PROTEIN; PREBIOTIC AGENT; SECRETORY IMMUNOGLOBULIN; TRANSFORMING GROWTH FACTOR BETA;

ABSORPTION; ANTIMICROBIAL ACTIVITY; ARTICLE; BREAST MILK; ENZYME ACTIVITY; GROWTH INHIBITION; GROWTH STIMULATION; HUMAN; HUMAN TISSUE; IMMUNOMODULATION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS;

BREAST FEEDING; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; LACTOFERRIN; MILK PROTEINS; MILK, HUMAN; MURAMIDASE; NITROGEN; PROTEOLYSIS;

EID: 84874618740     PISSN: 10344810     EISSN: 14401754     Source Type: Journal    
DOI: 10.1111/jpc.12104     Document Type: Article

References (27)

1. Lönnerdal B,. Bioactive proteins in human milk: mechanisms of action. J. Pediatr. 2010; 156 (2 Suppl.): S26-30.
2. Dewey KG, Heinig MJ, Nommsen-Rivers LA,. Differences in morbidity between breast-fed and formula-fed infants. J. Pediatr. 1995; 126 (5 Pt 1): 696-702.
3. Isolauri E,. Development of healthy gut microbiota early in life. J. Paediatr. Child Health 2012; 48 (Suppl. 3): 1-6.
4. Kunz C, Lönnerdal B,. Casein and casein subunits in preterm milk, colostrum, and mature human milk. J. Pediatr. Gastroenterol. Nutr. 1990; 10: 454-461.
5. Kunz C, Lönnerdal B,. Re-evaluation of the whey protein/casein ratio of human milk. Acta Paediatr. 1992; 81: 107-112.
6. Andersson B, Porras O, Hanson LA, Lagergård T, Svanborg-Edén C,. Inhibition of attachment of Streptococcus pneumoniae and Haemophilus influenzae by human milk and receptor oligosaccharides. J. Infect. Dis. 1986; 153: 232-237.
7. Ruiz-Palacios GM, Calva JJ, Pickering LK, et al. Protection of breast-fed infants against Campylobacter diarrhea by antibodies in human milk. J. Pediatr. 1990; 116: 707-713.
8. Cravioto A, Tello A, Villafán H, Ruiz J, del Vedovo S, Neeser JR,. Inhibition of localized adhesion of enteropathogenic Escherichia coli to HEp-2 cells by immunoglobulin and oligosaccharide fractions of human colostrum and breast milk. J. Infect. Dis. 1991; 163: 1247-1255.
9. Wakabayashi H, Yamauchi K, Takase M,. Inhibitory effects of bovine lactoferrin and lactoferricin B on Enterobacter sakazakii. Biocontrol Sci. 2008; 13: 29-32.
10. Arnold RR, Brewer M, Gauthier JJ,. Bactericidal activity of human lactoferrin: sensitivity of a variety of microorganisms. Infect. Immun. 1980; 28: 893-898.
11. Davidson LA, Lönnerdal B,. Persistence of human milk proteins in the breast-fed infant. Acta Paediatr. Scand. 1987; 76: 733-740.
12. Kawakami H, Lönnerdal B,. Isolation and function of a receptor for human lactoferrin in human fetal intestinal brush-border membranes. Am. J. Physiol. 1991; 261 (5 Pt 1): G841-846.
13. Suzuki YA, Shin K, Lönnerdal B,. Molecular cloning and functional expression of a human intestinal lactoferrin receptor. Biochemistry 2001; 40: 15771-15779.
14. Liao Y, Jiang R, Lönnerdal B,. Biochemical and molecular impacts of lactoferrin on small intestinal growth and development during early life. Biochem. Cell Biol. 2012; 90: 476-484.
15. Chandan RC, Parry RM, Shahani KM,. Lysozyme, lipase, and ribonuclease in milk of various species. J. Dairy Sci. 1968; 51: 606-607.
16. Ellison RT 3rd, Giehl TJ,. Killing of Gram-negative bacteria by lactoferrin and lysozyme. J. Clin. Invest. 1991; 88: 1080-1091.
17. Adkins Y, Lönnerdal B,. Mechanisms of vitamin B12 absorption in breast-fed infants. J. Pediatr. Gastroenterol. Nutr. 2002; 35: 192-198.
18. Adkins Y, Lönnerdal B,. Potential host-defense role of a human milk vitamin B-12-binding protein, haptocorrin, in the gastrointestinal tract of breastfed infants, as assessed with porcine haptocorrin in vitro. Am. J. Clin. Nutr. 2003; 77: 1234-1240.
19. Andersson Y, Sävman K, Bläckberg L, Hernell O,. Pasteurization of mother's own milk reduces fat absorption and growth in preterm infants. Acta Paediatr. 2007; 96: 1445-1449.
20. Strömqvist M, Falk P, Bergström S, et al. Human milk kappa-casein and inhibition of Helicobacter pylori adhesion to human gastric mucosa. J. Pediatr. Gastroenterol. Nutr. 1995; 21: 288-296.
21. Miehlke S, Reddy R, Osato MS, Ward PP, Conneely OM, Graham DY,. Direct activity of recombinant human lactoferrin against Helicobacter pylori. J. Clin. Microbiol. 1996; 34: 2593-2594.
22. Yolken RH, Peterson JA, Vonderfecht SL, Fouts ET, Midthun K, Newburg DS,. Human milk mucin inhibits rotavirus replication and prevents experimental gastroenteritis. J. Clin. Invest. 1992; 90: 1984-1991.
23. Schroten H, Hanisch FG, Plogmann R, et al. Inhibition of adhesion of S-fimbriated Escherichia coli to buccal epithelial cells by human milk fat globule membrane components: a novel aspect of the protective function of mucins in the nonimmunoglobulin fraction. Infect. Immun. 1992; 60: 2893-2899.
24. Zavaleta N, Kvistgaard AS, Graverholt G, et al. Efficacy of an MFGM-enriched complementary food in diarrhea, anemia, and micronutrient status in infants. J. Pediatr. Gastroenterol. Nutr. 2011; 53: 561-568.
25. Suzuki YA, Kelleher SL, Yalda D, et al. Expression, characterization, and biologic activity of recombinant human lactoferrin in rice. J. Pediatr. Gastroenterol. Nutr. 2003; 36: 190-199.
26. Huang J, Wu L, Yalda D, et al. Expression of functional recombinant human lysozyme in transgenic rice cell culture. Transgenic Res. 2002; 11: 229-239.
27. Zavaleta N, Figueroa D, Rivera J, Sánchez J, Alfaro S, Lönnerdal B,. Efficacy of rice-based oral rehydration solution containing recombinant human lactoferrin and lysozyme in Peruvian children with acute diarrhea. J. Pediatr. Gastroenterol. Nutr. 2007; 44: 258-264.