Mouse model of chromosome 15q13.3 microdeletion syndrome demonstrates features related to autism spectrum disorder

Journal of Neuroscience

Volumn 35, Issue 49, 2015, Pages 16282-16294

  Kogan, Jeffrey H ^a   Gross, Adam K ^a   Featherstone, Robert E ^d   Shin, Rick ^a   Chen, Qian ^a   Heusner, Carrie L ^a   Adachi, Megumi ^a   Lin, Amy ^a   Walton, Noah M ^a   Miyoshi, Sosuke ^b   Miyake, Shinichi ^a   Tajinda, Katsunori ^a   Ito, Hiroyuki ^a   Siege, Steven J ^d   Matsumoto, Mitsuyuki ^a,c  

^a ASTELLAS PHARMA GLOBAL DEVELOPMENT   (United States)

^b Translational Science Research Labs   (United States)

^c ASTELLAS PHARMA INC   (Japan)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

15q13.3; Autism; CNV; Epilepsy; Intellectual disability; Schizophrenia

Indexed keywords

PILOCARPINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY STIMULATION; AUTISM; CHROMOSOME 15Q; CHROMOSOME 15Q13.3 MICRODELETION SYNDROME; CHROMOSOME DELETION; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; ELEVATED ZERO MAZE TEST; EVENT RELATED POTENTIAL; FEMALE; GENE EXPRESSION; GROOMING; HUMAN; LEARNING; LONG TERM MEMORY; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN FIELD TEST; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SMELLING; SOCIAL INTERACTION TEST; VISUAL DISCRIMINATION; Y-MAZE TEST; ANIMAL; ANXIETY; BRAIN; C57BL MOUSE; CHROMOSOME 15; CHROMOSOME DISORDER; DRUG EFFECTS; ETIOLOGY; EVOKED RESPONSE; GENETICS; HUMAN RELATION; INTELLECTUAL IMPAIRMENT; MEMORY; METABOLISM; ODOR; PATHOLOGY; PATHOPHYSIOLOGY; PERCEPTIVE DISCRIMINATION; PHYSIOLOGY; SEIZURE; TRANSGENIC MOUSE; VOCALIZATION;

ANIMALS; ANXIETY; ASSOCIATION LEARNING; AUTISM SPECTRUM DISORDER; BRAIN; CHROMOSOME DELETION; CHROMOSOME DISORDERS; CHROMOSOMES, HUMAN, PAIR 15; DISCRIMINATION (PSYCHOLOGY); EVOKED POTENTIALS; FEMALE; GENE EXPRESSION; GROOMING; HUMANS; INTELLECTUAL DISABILITY; INTERPERSONAL RELATIONS; MALE; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PILOCARPINE; SEIZURES; SMELL; VOCALIZATION, ANIMAL;

EID: 84949567712     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3967-14.2015     Document Type: Article

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